GPVI-mediated activation cascade

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PDPK1PDPK1:PIP3PIP3GPVI:FceRI gamma:FYN:LYN:Collagen type IADPATPGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type ISYKGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:SYKGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:p-Y348-SYKP48025VAV1 Rho/Rac effectors:GDPGDPVAV1 Rho/Rac effectors:GTPGTPVAV2 Rho/Rac effectors:GTPVAV2 Rho/Rac effectors:GDPVAV3 Rho/Rac effectors:GDPVAV3 Rho/Rac effectors:GTPLatO54957Lcp2Q60787Plcg2Q8CIH5VAV1,2,3p-SLP-76:VAVPIP2IP3DAGPI3K betaPI3K gammaG6BG6B:PTPN6,PTPN11SHP1,SHP2PdpnCLEC1B dimer:PDPNCLEC1B dimerp-Y7-CLEC1B dimer:PDPNp-Y7-CLEC1B dimer:PDPN:SYK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000138 Q9JL99 C-type lectin domain family 1 member B view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025