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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

P26450

Gene Symbol

Pik3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P26450
PubChem: P26450
O-GlcNAcAtlas: P26450

Annotation

Keyword

Acetylation
Direct protein sequencing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of smooth muscle cell proliferation
negative regulation of smooth muscle cell proliferation
response to glucocorticoid
positive regulation of synapse assembly
regulation of protein localization to plasma membrane
protein stabilization
positive regulation of filopodium assembly
regulation of stress fiber assembly
negative regulation of stress fiber assembly
growth hormone receptor signaling pathway

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
perinuclear endoplasmic reticulum membrane
cytosol
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA

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GO Term
signaling receptor binding
insulin binding
kinase activator activity
protein kinase binding
ATPase binding
protein domain specific binding
nuclear estrogen receptor binding
ubiquitin protein ligase binding
ErbB-3 class receptor binding
insulin receptor substrate binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
541			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
PI-3K cascade:FGFR2	Mus musculus
PI-3K cascade:FGFR3	Mus musculus
PI-3K cascade:FGFR4	Mus musculus
PI3K Cascade	Mus musculus
PI3K events in ERBB2 signaling	Mus musculus
PI3K events in ERBB4 signaling	Mus musculus
PI3K/AKT Signaling	Mus musculus
PI3K/AKT activation	Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAC1 GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements