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MIRAGE
Phosphatidylinositol 3-kinase regulatory subunit alpha
Summary
- UniProt ID
- P26450
- Gene Symbol
-
- Pik3r1
- Gene ID
- 18708
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Direct protein sequencing
- Phosphoprotein
- Protein transport
- Reference proteome
- Repeat
- SH2 domain
- SH3 domain
- Stress response
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| phosphotyrosine residue binding |
| insulin-like growth factor receptor binding |
| neurotrophin TRKA receptor binding |
| phosphatidylinositol 3-kinase regulator activity |
Sequence
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI-3K cascade:FGFR2 | Mus musculus |
| PI-3K cascade:FGFR3 | Mus musculus |
| PI-3K cascade:FGFR4 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K events in ERBB2 signaling | Mus musculus |
| PI3K events in ERBB4 signaling | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI3K/AKT activation | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| RAC1 GTPase cycle | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111454 | SHORT syndrome | |
| DOID:14179 | X-linked agammaglobulinemia |
