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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

P26450

Gene Symbol

Pik3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P26450
PubChem: P26450
O-GlcNAcAtlas: P26450

Annotation

Keyword

Acetylation
Direct protein sequencing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

Displaying entries **41 - 50** of 52 in total

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GO Term
negative regulation of blood pressure
insulin-like growth factor receptor signaling pathway
protein import into nucleus
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of lamellipodium assembly
response to endoplasmic reticulum stress
regulation of toll-like receptor 4 signaling pathway
interleukin-18-mediated signaling pathway
positive regulation of protein import into nucleus

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
perinuclear endoplasmic reticulum membrane
cytosol
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA

Displaying entries **11 - 20** of 24 in total

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GO Term
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
phosphoprotein binding
phosphotyrosine residue binding
1-phosphatidylinositol-3-kinase activity
insulin receptor binding
insulin-like growth factor receptor binding
platelet-derived growth factor receptor binding
neurotrophin TRKA receptor binding
calmodulin binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
541			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **51 - 55** of 55 in total

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Pathway Name	Organism
Signaling by LTK	Mus musculus
Signaling by SCF-KIT	Mus musculus
Synthesis of PIPs at the plasma membrane	Mus musculus
Tie2 Signaling	Mus musculus
VEGFA-VEGFR2 Pathway	Mus musculus