Tie2 Signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TEKANGPT1:TEKAngpt12xANGPT1:TEKPI3Kp85 bound to Tie2ANGPT1:p-5Y,S119-TEKGrb2Grb2 bound to Tie2SOS-1 bound to Tie2:Grb2Sos1p21 RAS:GDPp21 RAS:GTPGDPGTPANGPT1:p-5Y,S119-TEK:SHC1Shc1Tie2 and Dok-2 complexDok2ANGPT2ANGPT2:TEKANGPT4:TEKAngpt4pTie2 and SHP2 complexPTPN11Tie2:Grb7 complexGrb7Grb14Tie2 and Grb14 complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025