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Phosphatidylinositol 3-kinase regulatory subunit alpha

Summary

UniProt ID

P26450

Gene Symbol

Pik3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P26450
PubChem: P26450
O-GlcNAcAtlas: P26450

Annotation

Keyword

Acetylation
Direct protein sequencing
Phosphoprotein
Protein transport
Reference proteome
Repeat
SH2 domain
SH3 domain
Stress response
Ubl conjugation

Gene Ontology (GO)

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GO Term
intracellular glucose homeostasis
positive regulation of protein phosphorylation
positive regulation of leukocyte migration
glucose metabolic process
negative regulation of cell adhesion
insulin receptor signaling pathway
positive regulation of gene expression
B cell differentiation
osteoclast differentiation
positive regulation of cell migration

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GO Term
nucleus
cytoplasm
cell-cell junction
membrane
protein-containing complex
perinuclear endoplasmic reticulum membrane
cytosol
cis-Golgi network
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA

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GO Term
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
phosphoprotein binding
phosphotyrosine residue binding
1-phosphatidylinositol-3-kinase activity
insulin receptor binding
insulin-like growth factor receptor binding
platelet-derived growth factor receptor binding
neurotrophin TRKA receptor binding
calmodulin binding

Annotation information from UniProt.

Sequence

MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSDNTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
541			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
G alpha (q) signalling events	Mus musculus
GAB1 signalosome	Mus musculus
GP1b-IX-V activation signalling	Mus musculus
GPVI-mediated activation cascade	Mus musculus
IRS-mediated signalling	Mus musculus
Interleukin receptor SHC signaling	Mus musculus
Interleukin-3, Interleukin-5 and GM-CSF signaling	Mus musculus
Interleukin-7 signaling	Mus musculus
MET activates PI3K/AKT signaling	Mus musculus
PI-3K cascade:FGFR1	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements