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Platelet-derived growth factor receptor alpha

Summary

UniProt ID

P26618

Gene Symbol

Pdgfra

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003518
PubChem: P26618

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cell projection
Chemotaxis
Developmental protein
Disulfide bond
Glycoprotein
Golgi apparatus
Immunoglobulin domain
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 46 in total

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GO Term
luteinization
in utero embryonic development
hematopoietic progenitor cell differentiation
positive regulation of cell population proliferation
female gonad development
anatomical structure morphogenesis
animal organ morphogenesis
cell migration
peptidyl-tyrosine phosphorylation
positive regulation of cell migration

Displaying entries **1 - 10** of 13 in total

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GO Term
nucleus
cytoplasm
Golgi apparatus
plasma membrane
microvillus
cilium
axon
protein-containing complex
cell junction
receptor complex

Displaying **all 10** entries
GO Term
ATP binding
protein kinase activity
protein-containing complex binding
protein homodimerization activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor receptor activity
platelet-derived growth factor receptor binding
vascular endothelial growth factor binding
platelet-derived growth factor binding
phosphatidylinositol 3-kinase binding

Annotation information from UniProt.

Sequence

MGTSHQVFLVLSCLLTGPGLISCQLLLPSILPNENEKIVQLNSSFSLRCVGESEVSWQHPMSEEDDPNVEIRSEENNSGLFVTVLEVVNASAAHTGWYTCYYNHTQTDESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPETQVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVKGRTFKTSEFNVYALKATSELNLEMDARQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGEYECAARQATKEVKEMKRVTISVHEKGFVEIEPTFGQLEAVNLHEVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQKSQETRYQSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELSTLVPASILDLVDDHHGSGGGQTVRCTAEGTPLPEIDWMICKHIKKCNNDTSWTVLASNVSNIITELPRRGRSTVEGRVSFAKVEETIAVRCLAKNNLSVVARELKLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSQHPEKPKKDLDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	Source
42	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
76	N-linked (GlcNAc...) asparagine	UniProt
89	N-linked (GlcNAc...) asparagine	UniProt
103	N-linked (GlcNAc...) asparagine	UniProt
179	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
353	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
359	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
458	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
468	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
506	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Downstream signal transduction	Mus musculus
PI3K/AKT Signaling	Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
Signaling by PDGF	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements