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Vasopressin V2 receptor

Summary

UniProt ID

P30518

Gene Symbol

AVPR2
ADHR
DIR
DIR3
V2R

Organism

Homo sapiens (human)

External Links

GlyGen: P30518
PubChem: P30518
The Human Metabolome Database: HMDBP01725
The O-GlcNAc Database: P30518

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Diabetes insipidus
Disease variant
G-protein coupled receptor
Glycoprotein
Palmitate
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

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2

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GO Term
telencephalon development
cellular response to hormone stimulus
response to cytokine
positive regulation of intracellular signal transduction
positive regulation of vasoconstriction
positive regulation of systemic arterial blood pressure
renal water retention
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
activation of adenylate cyclase activity
regulation of systemic arterial blood pressure by vasopressin

Displaying **all 8** entries
GO Term
clathrin-coated endocytic vesicle membrane
endosome
endoplasmic reticulum
Golgi apparatus
plasma membrane
membrane
endocytic vesicle
perinuclear region of cytoplasm

Displaying **all 2** entries
GO Term
vasopressin receptor activity
peptide binding

Annotation information from UniProt.

Sequence

MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
22	N-linked (GlcNAc...) asparagine			UniProt GlyGen
350			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Homo sapiens
Clathrin-mediated endocytosis	Homo sapiens
Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	Homo sapiens
G alpha (s) signalling events	Homo sapiens
Vasopressin regulates renal water homeostasis via Aquaporins	Homo sapiens
Vasopressin-like receptors	Homo sapiens