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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Vasopressin V2 receptor
Summary
- UniProt ID
- P30518
- Gene Symbol
-
- AVPR2
- ADHR
- DIR
- DIR3
- V2R
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P30518
- PubChem
- P30518
- The Human Metabolome Database
- HMDBP01725
- The O-GlcNAc Database
- P30518
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Diabetes insipidus
- Disease variant
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| G protein-coupled receptor signaling pathway |
| hemostasis |
| positive regulation of cell population proliferation |
| negative regulation of cell population proliferation |
| positive regulation of gene expression |
| GO Term |
|---|
| clathrin-coated endocytic vesicle membrane |
| endosome |
| endoplasmic reticulum |
| perinuclear region of cytoplasm |
| Golgi apparatus |
| plasma membrane |
| membrane |
| endocytic vesicle |
| GO Term |
|---|
| vasopressin receptor activity |
| peptide binding |
Sequence
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 22 | N-linked (GlcNAc...) asparagine |
|
||
| 350 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) | Homo sapiens |
| G alpha (s) signalling events | Homo sapiens |
| Vasopressin regulates renal water homeostasis via Aquaporins | Homo sapiens |
| Vasopressin-like receptors | Homo sapiens |
