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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dual specificity mitogen-activated protein kinase kinase 4
Summary
- UniProt ID
- P45985
- Gene Symbol
-
- MAP2K4
- JNKK1
- MEK4
- MKK4
- PRKMK4
- SEK1
- SERK1
- SKK1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P45985
- PubChem
- P45985
- The Human Metabolome Database
- HMDBP01366
- The O-GlcNAc Database
- P45985
- O-GlcNAcAtlas
- P45985
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cytoplasm
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Stress response
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| axon |
| dendrite cytoplasm |
| perikaryon |
| cytosol |
| nucleus |
Sequence
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 7 |
|
|||
| 20 |
|
|
||
| 36 |
|
|||
| 391 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FCERI mediated MAPK activation | Homo sapiens |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Homo sapiens |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | Homo sapiens |
| Oxidative Stress Induced Senescence | Homo sapiens |
| Uptake and function of anthrax toxins | Homo sapiens |
Human Protein Atlas