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MIRAGE
Uptake and function of anthrax toxins

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TEM8pagA:ANTXR1PA83CMG2pagA:ANTXR2PA20PA63:ANTXR1PA63:ANTXR2FURINFURIN:FURIN inhibitorsFURIN inhibitors8(PA63:ANTXR1)8(PA63:ANTXR2)EFEF:LF:8(PA63:ANTXR1)LFEF:LF:8(PA63:ANTXR2)EF:LF:8(PA63:ANTXR1)EF:LF:8(PA63:ANTXR2)8(PA63:ANTXR1)LFEF8(PA63:ANTXR2)ATPPPicAMPMEK1MAP2K1(9-393)MAP2K1(2-8)MEK2MAP2K2(11-400)MAP2K2(1-10)MAP2k3bMAP2k3b(1-26)MAP2k3b(27-347)SEK1MAP2K4(?-399)MAP2K4(1-?)MAP2K6bMAP2K6-1(15-334)MAP2K6-1(1-14)MKK7MAP2K7(2-?)MAP2K7(?-419)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P09958 Furin
  • FUR
  • FURIN
  • PACE
  • PCSK3
 view
P36507 Dual specificity mitogen-activated protein kinase kinase 2
  • MAP2K2
  • MEK2
  • MKK2
  • PRKMK2
 view
P45985 Dual specificity mitogen-activated protein kinase kinase 4
  • JNKK1
  • MAP2K4
  • MEK4
  • MKK4
  • PRKMK4
  • SEK1
  • SERK1
  • SKK1
 view
Q02750 Dual specificity mitogen-activated protein kinase kinase 1
  • MAP2K1
  • MEK1
  • PRKMK1
 view
Q8WUM4 Programmed cell death 6-interacting protein
  • AIP1
  • ALIX
  • KIAA1375
  • PDCD6IP
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025