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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Furin
Summary
- UniProt ID
- P09958
- Gene Symbol
-
- FURIN
- FUR
- PACE
- PCSK3
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P09958
- PubChem
- P09958
- The Human Metabolome Database
- HMDBP07695
Annotation
- Keyword
-
- 3D-structure
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Endosome
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Host-virus interaction
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Transmembrane helix
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| membrane raft |
| endoplasmic reticulum |
| endosome membrane |
| Golgi lumen |
| trans-Golgi network |
| cell surface |
| trans-Golgi network transport vesicle |
| Golgi membrane |
| extracellular region |
| plasma membrane |
Sequence
MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Homo sapiens |
| Amyloid fiber formation | Homo sapiens |
| Assembly of active LPL and LIPC lipase complexes | Homo sapiens |
| Attachment and Entry | Homo sapiens |
| CD163 mediating an anti-inflammatory response | Homo sapiens |
| Collagen degradation | Homo sapiens |
| Elastic fibre formation | Homo sapiens |
| Formation of the cornified envelope | Homo sapiens |
| Induction of Cell-Cell Fusion | Homo sapiens |
| Maturation of hRSV A proteins | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
