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Interleukin-2

Summary

UniProt ID

P60568

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P60568

PubChem

P60568

Annotation

Keyword

3D-structure
Adaptive immunity
Chromosomal rearrangement
Cytokine
Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor
Pharmaceutical
Proto-oncogene
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 38 in total

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GO Term
response to ethanol
positive regulation of isotype switching to IgG isotypes
transcription by RNA polymerase II
positive regulation of transcription by RNA polymerase II
interleukin-2-mediated signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G protein-coupled receptor signaling pathway
positive regulation of activated T cell proliferation
positive regulation of tyrosine phosphorylation of STAT protein
activated T cell proliferation

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Displaying **all 7** entries
GO Term
kappa-type opioid receptor binding
cytokine activity
interleukin-2 receptor binding
growth factor activity
glycosphingolipid binding
kinase activator activity
carbohydrate binding

Annotation information from UniProt.

Sequence

MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
23	O-linked (GalNAc...) threonine	2793860 6333684	G01614ZM G81006GJ G65562ZE G74722FL G00031MO G29931IJ	UniProt GlyGen GlyConnect
			G23863VK G97037FD G22140GZ G50045TK G37969WK G46687AB G02561FC G81295CK G10374FO G49874UX G39943KJ G74724QE G82348BZ G00395TQ G31685JQ G18220BL G14227RA G74722FL G00031MO G29931IJ G57321FI	GlyGen GlyConnect GlyConnect GlyConnect GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Interleukin receptor SHC signaling	Homo sapiens
Interleukin-2 signaling	Homo sapiens
RAF/MAP kinase cascade	Homo sapiens
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Homo sapiens