Interleukin-2 signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-STAT5p-STAT5 dimerp-STAT5 dimerIL2IL2:IL2RACD25JAK1IL2RB:JAK1IL2RBIL2:IL2RA:IL2RB:JAK1JAK3IL2RG:JAK3IL2RGIL2:IL2R trimer:JAK1:JAK3IL2:IL2R trimer:p-JAK1:JAK3ATPADPIL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHCSHCSTAT5IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHCIL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5SYKIL2:IL2R trimer:p-JAK1:JAK3:SYKIL2:IL2R trimer:p-JAK1:JAK3:p-SYKPTK2BJAK3:PYK2JAK3:p-PYK2JAK3:JAK3 inhibitorsJAK3 inhibitors
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025