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MIRAGE
Tyrosine-protein kinase JAK3
Summary
- UniProt ID
- P52333
- Gene Symbol
-
- JAK3
- Gene ID
- 3718
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P52333
- PubChem
- P52333
- The Human Metabolome Database
- HMDBP01358
- The O-GlcNAc Database
- P52333
- Re-Glyco
- P52333
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Adaptive immunity
- Alternative splicing
- Cytoplasm
- Disease variant
- Innate immunity
- Membrane
- Phosphoprotein
- Reference proteome
- Repeat
- SCID
- SH2 domain
- Tyrosine-protein kinase
- Gene Ontology (GO)
Sequence
MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 792 |
|
|
||
| 890 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin receptor SHC signaling | Homo sapiens |
| Interleukin-15 signaling | Homo sapiens |
| Interleukin-2 signaling | Homo sapiens |
| Interleukin-20 family signaling | Homo sapiens |
| Interleukin-21 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Interleukin-7 signaling | Homo sapiens |
| Interleukin-9 signaling | Homo sapiens |
| Potential therapeutics for SARS | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0081042 | T-cell prolymphocytic leukemia | |
| DOID:0081312 | T-cell non-Hodgkin lymphoma | |
| DOID:5603 | T-cell acute lymphoblastic leukemia | |
| DOID:627 | severe combined immunodeficiency | |
| DOID:8761 | acute megakaryocytic leukemia |
