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60 kDa heat shock protein, mitochondrial

Summary

UniProt ID

P63039

Gene Symbol

Hsp60
Hspd1

Gene ID

63868

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P63039
PubChem: P63039
The O-GlcNAc Database: P63039
RaftProt: P63039
O-GlcNAcAtlas: P63039
Re-Glyco: P63039

Annotation

Keyword

ATP-binding
Acetylation
Chaperone
Direct protein sequencing
Isomerase
Isopeptide bond
Mitochondrion
Phosphoprotein
Reference proteome
Transit peptide
Ubl conjugation

Gene Ontology (GO)

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GO Term
extracellular space
protein-containing complex
zymogen granule
intracellular membrane-bounded organelle
early endosome
cytosol
cell surface
Golgi cisterna
peroxisomal matrix
clathrin-coated pit

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
response to glucocorticoid
negative regulation of reactive oxygen species biosynthetic process
response to resveratrol
response to organic cyclic compound
positive regulation of interleukin-12 production
MyD88-dependent toll-like receptor signaling pathway
'de novo' protein folding
apoptotic mitochondrial changes
positive regulation of interleukin-10 production
positive regulation of type II interferon production

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GO Term
protein-folding chaperone binding
ATP-dependent protein folding chaperone
lipopolysaccharide binding
high-density lipoprotein particle binding
apolipoprotein A-I binding
modification-dependent protein binding
p53 binding
double-stranded RNA binding
ATP binding
enzyme binding

Annotation information from UniProt.

Sequence

MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
54		GlyGen
67	G49108TO	GlyGen The O-GlcNAc Database
398	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Mitochondrial protein degradation	Rattus norvegicus
Mitochondrial protein import	Rattus norvegicus

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:13544	low tension glaucoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements