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60 kDa heat shock protein, mitochondrial

Summary

UniProt ID

P63039

Gene Symbol

Hspd1
Hsp60

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P63039
PubChem: P63039
The O-GlcNAc Database: P63039
RaftProt: P63039
O-GlcNAcAtlas: P63039

Annotation

Keyword

ATP-binding
Acetylation
Chaperone
Direct protein sequencing
Isomerase
Isopeptide bond
Mitochondrion
Phosphoprotein
Reference proteome
Transit peptide
Ubl conjugation

Gene Ontology (GO)

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GO Term
positive regulation of type II interferon production
B cell proliferation
T cell activation
B cell activation
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of T cell activation
MyD88-dependent toll-like receptor signaling pathway
positive regulation of T cell mediated immune response to tumor cell
isotype switching to IgG isotypes

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GO Term
early endosome
membrane
secretory granule
protein-containing complex
zymogen granule
intracellular membrane-bounded organelle
peroxisomal matrix
sperm plasma membrane
mitochondrial crista
lipopolysaccharide receptor complex

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GO Term
lipopolysaccharide binding
isomerase activity
high-density lipoprotein particle binding
apolipoprotein A-I binding
modification-dependent protein binding
p53 binding
double-stranded RNA binding
ATP binding
enzyme binding
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEEKDPGMGAMGGMGGGMGGGMF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites