low tension glaucoma

Summary
Synonym
  • Normal tension glaucoma
Definition
An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision.
Super Class
open-angle glaucoma
Disease Ontology
DOID:13544
Mondo Disease Ontology
MeSH
UMLS
MGI genotype (from TogoID)
Related Genes
Displaying all 7 entries
Gene ID Gene Symbol Description Source
153 ADRB1 adrenoceptor beta 1
348 APOE apolipoprotein E
4653 MYOC myocilin
7099 TLR4 toll like receptor 4
7124 TNF tumor necrosis factor
7157 TP53 tumor protein p53
10133 OPTN optineurin
Displaying all 3 entries
Gene ID Gene Symbol Description Source
20510 Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
20512 Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
20655 Sod1 superoxide dismutase 1, soluble
Displaying 1 entry
Gene ID Gene Symbol Description Source
63868 Hspd1 heat shock protein family D (Hsp60) member 1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025