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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
HLA class II histocompatibility antigen, DR beta 3 chain
Summary
- UniProt ID
- P79483
- Gene Symbol
-
- HLA-DRB3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Lysosome
- MHC II
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| clathrin-coated endocytic vesicle membrane |
| late endosome membrane |
| ER to Golgi transport vesicle membrane |
| GO Term |
|---|
| MHC class II receptor activity |
| peptide antigen binding |
| MHC class II protein complex binding |
Sequence
MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
Glycosylation Sites
G84452RH
G80920RR
G62765YT
G47644PP
G31852PQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream TCR signaling | Homo sapiens |
| Generation of second messenger molecules | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| MHC class II antigen presentation | Homo sapiens |
| PD-1 signaling | Homo sapiens |
| Phosphorylation of CD3 and TCR zeta chains | Homo sapiens |
| Translocation of ZAP-70 to Immunological synapse | Homo sapiens |
