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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Receptor-type tyrosine-protein kinase FLT3
Summary
- UniProt ID
- Q00342
- Gene Symbol
-
- Flt3
- Flk-2
- Flt-3
- Organism
- Mus musculus (house mouse)
External Links
- PubChem
- Q00342
Annotation
- Keyword
-
- ATP-binding
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Proto-oncogene
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| protein-containing complex |
| receptor complex |
| endoplasmic reticulum lumen |
| external side of plasma membrane |
| cell surface |
Sequence
MRALAQRSDRRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRMVRGSPEDLQCTPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQPHFDLQNRGIVSMAILNVTETQAGEYLLHIQSEAANYTVLFTVNVRDTQLYVLRRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKVLHELFGTDIRCCARNALGRESTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELEDKALEEGSYFEMSTYSTNRTMIRILLAFVSSVGRNDTGYYTCSSSKHPSQSALVTILEKGFINATSSQEEYEIDPYEKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISKFCDHKNKPGEYIFYAENDDAQFTKMFTLNIRKKPQVLANASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPEGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFLNSPGPFPFIQDNISFYATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQAHSNSSMPGSREVQLHPPLDQLSGFNGNSIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEEAMYQNMGGNVPEHPSIYQNRRPLSREAGSEPPSPQAQVKIHRERS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 44 | N-linked (GlcNAc...) asparagine |
|
||
| 133 | N-linked (GlcNAc...) asparagine |
|
||
| 152 | N-linked (GlcNAc...) asparagine |
|
||
| 307 | N-linked (GlcNAc...) asparagine |
|
||
| 324 | N-linked (GlcNAc...) asparagine |
|
||
| 352 | N-linked (GlcNAc...) asparagine |
|
||
| 445 | N-linked (GlcNAc...) asparagine |
|
||
| 474 | N-linked (GlcNAc...) asparagine |
|
||
| 503 | N-linked (GlcNAc...) asparagine |
|
||
| 542 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FLT3 Signaling | Mus musculus |
| FLT3 signaling through SRC family kinases | Mus musculus |
| Negative regulation of FLT3 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
