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Melanocyte-stimulating hormone receptor

Summary

UniProt ID

Q01726

Gene Symbol

MC1R
MSHR

Gene ID

4157

Organism

Homo sapiens (human)

External Links

GlyGen: Q01726
PubChem: Q01726
Re-Glyco: Q01726

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
G-protein coupled receptor
Glycoprotein
Palmitate
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
cytoplasm
plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 13 in total

1

2

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GO Term
adenylate cyclase-activating G protein-coupled receptor signaling pathway
negative regulation of tumor necrosis factor production
UV-damage excision repair
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
phospholipase C-activating G protein-coupled receptor signaling pathway
melanin biosynthetic process
positive regulation of feeding behavior
regulation of metabolic process
sensory perception of pain
intracellular signal transduction

Displaying **all 5** entries
GO Term
ubiquitin protein ligase binding
hormone binding
G protein-coupled peptide receptor activity
melanocortin receptor activity
melanocyte-stimulating hormone receptor activity

Annotation information from UniProt.

Sequence

MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
29	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
G alpha (s) signalling events	Homo sapiens
Peptide ligand-binding receptors	Homo sapiens
Transcriptional and post-translational regulation of MITF-M expression and activity	Homo sapiens

Disease

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0070096	oculocutaneous albinism type II	Alliance of Genome Resources
DOID:10123	pigmentation disease	Alliance of Genome Resources
DOID:1470	major depressive disorder	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources
DOID:6846	familial melanoma	Alliance of Genome Resources