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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Galactoside alpha-(1,2)-fucosyltransferase 2
Summary
- UniProt ID
- Q10981
- Gene Symbol
-
- FUT2
- SEC2
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q10981
- The Human Metabolome Database
- HMDBP00466
Annotation
- Keyword
-
- Blood group antigen
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Lipid metabolism
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| Golgi apparatus |
| extracellular exosome |
| Golgi cisterna membrane |
| GO Term |
|---|
| galactoside 2-alpha-L-fucosyltransferase activity |
| fucosyltransferase activity |
| alpha-(1,2)-fucosyltransferase activity |
Sequence
MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABO blood group biosynthesis | Homo sapiens |
| Glycosphingolipid biosynthesis | Homo sapiens |
| Lewis blood group biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111029 | hemochromatosis type 1 | |
| DOID:10534 | stomach cancer | |
| DOID:10604 | lactose intolerance | |
| DOID:10608 | celiac disease | |
| DOID:10754 | otitis media | |
| DOID:11079 | leech infestation | |
| DOID:11080 | myiasis |
