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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Exosome complex component RRP42
Summary
- UniProt ID
- Q15024
- Gene Symbol
-
- EXOSC7
- KIAA0116
- RRP42
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cytoplasm
- Direct protein sequencing
- Exosome
- Nucleus
- Phosphoprotein
- RNA-binding
- Reference proteome
- rRNA processing
- Gene Ontology (GO)
| GO Term |
|---|
| exonucleolytic catabolism of deadenylated mRNA |
| RNA processing |
| exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO Term |
|---|
| nucleus |
| nucleolus |
| cytosol |
| nuclear exosome (RNase complex) |
| cytoplasmic exosome (RNase complex) |
| exosome (RNase complex) |
| nucleoplasm |
| nucleolar exosome (RNase complex) |
| GO Term |
|---|
| 3'-5'-RNA exonuclease activity |
| RNA binding |
Sequence
MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ATF4 activates genes in response to endoplasmic reticulum stress | Homo sapiens |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | Homo sapiens |
| KSRP (KHSRP) binds and destabilizes mRNA | Homo sapiens |
| Major pathway of rRNA processing in the nucleolus and cytosol | Homo sapiens |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | Homo sapiens |
| mRNA decay by 3' to 5' exoribonuclease | Homo sapiens |
