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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Growth factor receptor-bound protein 10
Summary
- UniProt ID
- Q60760
- Gene Symbol
-
- Grb10
- Meg1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Phosphoprotein
- Reference proteome
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of Wnt signaling pathway |
| response to insulin |
| negative regulation of insulin receptor signaling pathway |
| insulin-like growth factor receptor signaling pathway |
| ERK1 and ERK2 cascade |
| GO Term |
|---|
| cytosol |
| protein-containing complex |
| GO Term |
|---|
| phosphotyrosine residue binding |
| insulin receptor binding |
| signaling receptor complex adaptor activity |
| protein-macromolecule adaptor activity |
Sequence
MNNDINSSVESLNSACNMQSDTDTAPLLEDGQHASNQGAASSSRGQPQASPRQKMQRSQPVHILRRLQEEDQQLRTASLPAIPNPFPELTGAAPGSPPSVAPSSLPPPPSQPPAKHCGRCEKWIPGENTRGNGKRKIWRWQFPPGFQLSKLTRPGLWTKTTARFSKKQPKNQCPTDTVNPVARMPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTARDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVESTMPSESKFLFRKNYAKYEFFKNPVNFFPDQMVNWCQQSNGGQAQLLQNFLNTSSCPEIQGFLQVKEVGRKSWKKLYVCLRRSGLYYSTKGTSKEPRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIKPNKAKTEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYRIPQRKGLPPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEEGHAWRKRSTRMNILSSQSPLHPSTLNAVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL
Glycosylation Sites
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FLT3 Signaling | Mus musculus |
| IRS activation | Mus musculus |
| Insulin receptor signalling cascade | Mus musculus |
| RET signaling | Mus musculus |
| Signal attenuation | Mus musculus |
| Signaling by SCF-KIT | Mus musculus |
