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MIRAGE
Inducible T-cell costimulator

Summary
UniProt ID
Q9WVS0
Gene Symbol
  • Ailim
  • Icos
Gene ID
54167
Organism
Mus musculus (house mouse)
PubChem
Q9WVS0
Re-Glyco
Q9WVS0
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 2 entries
GO Term
external side of plasma membrane
plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
T cell costimulation
Annotation information from UniProt.
Sequence
MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
23 N-linked (GlcNAc...) asparagine
89 N-linked (GlcNAc...) asparagine
123 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Costimulation by the CD28 family Mus musculus
PI3K/AKT Signaling Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Mus musculus
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:12177 common variable immunodeficiency
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025