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2'-5'-oligoadenylate synthase 3

Summary

UniProt ID

Q9Y6K5

Gene Symbol

OAS3

Organism

Homo sapiens (human)

External Links

GlyGen: Q9Y6K5
PubChem: Q9Y6K5
The Human Metabolome Database: HMDBP08494
The O-GlcNAc Database: Q9Y6K5
O-GlcNAcAtlas: Q9Y6K5

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Antiviral defense
Cytoplasm
Direct protein sequencing
Innate immunity
Magnesium
Metal-binding
Nucleotidyltransferase
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Repeat

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

1

2

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GO Term
positive regulation of interferon-beta production
positive regulation of tumor necrosis factor production
RIG-I signaling pathway
positive regulation of monocyte chemotactic protein-1 production
negative regulation of viral genome replication
MDA-5 signaling pathway
negative regulation of IP-10 production
nucleobase-containing compound metabolic process
response to virus
defense response to bacterium

Displaying **all 7** entries
GO Term
nucleoplasm
cytosol
extracellular space
cytoplasm
plasma membrane
membrane
intracellular membrane-bounded organelle

Displaying **all 4** entries
GO Term
metal ion binding
double-stranded RNA binding
ATP binding
2'-5'-oligoadenylate synthetase activity

Annotation information from UniProt.

Sequence

MDLYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGSSGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTFPEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNSGCQGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIFAWEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPVILDPADPTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGCSGLGHPIQLDPNQKTPENSKSLNAVYPRAGSKPPSCPAPGPTGAASIVPSVPGMALDLSQIPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHENCVHKASRVSKGGSFGRGTDLRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLESWWQDQVPSLSLQFPEQNVPEALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLLTSGCQEGEHKACFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTIFAWEQGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPLVLDPADPTWNVGHGSWELLAQEAAALGMQACFLSRDGTSVQPWDVMPALLYQTPAGDLDKFISEFLQPNRQFLAQVNKAVDTICSFLKENCFRNSPIKVIKVVKGGSSAKGTALRGRSDADLVVFLSCFSQFTEQGNKRAEIISEIRAQLEACQQERQFEVKFEVSKWENPRVLSFSLTSQTMLDQSVDFDVLPAFDALGQLVSGSRPSSQVYVDLIHSYSNAGEYSTCFTELQRDFIISRPTKLKSLIRLVKHWYQQCTKISKGRGSLPPQHGLELLTVYAWEQGGKDSQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKDKTVGDFLKQQLQKPRPIILDPADPTGNLGHNARWDLLAKEAAACTSALCCMGRNGIPIQPWPVKAAV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites