GlyCosmos Portal

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Displaying entries **826 - 850** of **126547** in total

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UniProt ID	Gene Symbol	Organism	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	Gene Ontology ▲	Gene Ontology ID
O95861	BPNT1	Homo sapiens (human)	9606	1	1	3'(2'),5'-bisphosphate nucleotidase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process cytosol inositol-1,4-bisphosphate 1-phosphatase activity metal ion binding nervous system development nucleobase-containing compound metabolic process phosphatidylinositol phosphate biosynthetic process sulfate assimilation	GO:0000103 GO:0004441 GO:0005829 GO:0006139 GO:0007399 GO:0008441 GO:0046854 GO:0046872 GO:0050427
Q9Z0S1	Bpnt1	Mus musculus (house mouse)	10090	0	1	3'(2'),5'-bisphosphate nucleotidase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process inositol-1,4-bisphosphate 1-phosphatase activity magnesium ion binding phosphatidylinositol phosphate biosynthetic process sulfate assimilation	GO:0000103 GO:0000287 GO:0004441 GO:0008441 GO:0046854 GO:0050427
A0A1B0GRV0	Bpnt1	Mus musculus (house mouse)	10090	0	1	3'(2'),5'-bisphosphate nucleotidase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process metal ion binding phosphatidylinositol phosphate biosynthetic process sulfate assimilation	GO:0000103 GO:0008441 GO:0046854 GO:0046872 GO:0050427
V5AS37	TCDM_08573	Trypanosoma cruzi Dm28c	1416333	0	1	3'(2'),5'-bisphosphate nucleotidase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process sulfate assimilation	GO:0000103 GO:0008441 GO:0050427
Q08499	PDE4D DPDE3	Homo sapiens (human)	9606	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity ATPase binding T cell receptor signaling pathway adrenergic receptor signaling pathway apical plasma membrane beta-2 adrenergic receptor binding cAMP binding cAMP catabolic process cAMP-mediated signaling calcium channel complex calcium channel regulator activity cellular response to cAMP cellular response to epinephrine stimulus centrosome cytosol enzyme binding establishment of endothelial barrier heterocyclic compound binding membrane metal ion binding negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of cAMP-mediated signaling negative regulation of heart contraction negative regulation of peptidyl-serine phosphorylation negative regulation of relaxation of cardiac muscle nucleus perinuclear region of cytoplasm plasma membrane positive regulation of heart rate positive regulation of interleukin-2 production positive regulation of interleukin-5 production positive regulation of type II interferon production regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of cardiac muscle cell contraction regulation of cell communication by electrical coupling involved in cardiac conduction regulation of heart rate regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum scaffold protein binding signaling receptor regulator activity transmembrane transporter binding voltage-gated calcium channel complex	GO:0002027 GO:0004114 GO:0004115 GO:0005246 GO:0005634 GO:0005813 GO:0005829 GO:0005886 GO:0005891 GO:0006198 GO:0010460 GO:0010880 GO:0016020 GO:0016324 GO:0019899 GO:0019933 GO:0030545 GO:0030552 GO:0031698 GO:0032729 GO:0032743 GO:0032754 GO:0033137 GO:0034704 GO:0043951 GO:0044325 GO:0045822 GO:0046872 GO:0047555 GO:0048471 GO:0050852 GO:0051117 GO:0061028 GO:0071320 GO:0071872 GO:0071875 GO:0086004 GO:0097110 GO:0106072 GO:1901363 GO:1901844 GO:1901898 GO:1902514
Q01063	Pde4d	Mus musculus (house mouse)	10090	2	3	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity ATPase binding adrenergic receptor signaling pathway apical plasma membrane beta-2 adrenergic receptor binding cAMP catabolic process cAMP-mediated signaling calcium channel complex calcium channel regulator activity cellular response to cAMP cellular response to epinephrine stimulus cellular response to follicle-stimulating hormone stimulus cellular response to lipopolysaccharide centrosome cyclic-nucleotide phosphodiesterase activity cytosol enzyme binding establishment of endothelial barrier memory metal ion binding multicellular organism growth myofibril negative regulation of cAMP-mediated signaling negative regulation of heart contraction negative regulation of peptidyl-serine phosphorylation negative regulation of relaxation of cardiac muscle neutrophil chemotaxis neutrophil migration nucleus ovulation from ovarian follicle perinuclear region of cytoplasm positive regulation of cell-cell adhesion positive regulation of heart rate positive regulation of protein phosphorylation positive regulation of smooth muscle cell migration positive regulation of smooth muscle cell proliferation potassium channel complex protein-containing complex assembly protein-containing complex regulation of G protein-coupled receptor signaling pathway regulation of cAMP-mediated signaling regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of cardiac muscle cell contraction regulation of cell communication by electrical coupling involved in cardiac conduction regulation of heart rate regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum signaling receptor regulator activity smooth muscle contraction transmembrane transporter binding voltage-gated calcium channel complex	GO:0001542 GO:0001934 GO:0002027 GO:0004112 GO:0004114 GO:0004115 GO:0005246 GO:0005634 GO:0005813 GO:0005829 GO:0005891 GO:0006198 GO:0006939 GO:0007613 GO:0008277 GO:0010460 GO:0010880 GO:0014911 GO:0016324 GO:0019899 GO:0019933 GO:0022409 GO:0030016 GO:0030545 GO:0030593 GO:0031698 GO:0032991 GO:0033137 GO:0034704 GO:0034705 GO:0035264 GO:0043949 GO:0043951 GO:0044325 GO:0045822 GO:0046872 GO:0047555 GO:0048471 GO:0048661 GO:0051117 GO:0061028 GO:0065003 GO:0071222 GO:0071320 GO:0071372 GO:0071872 GO:0071875 GO:0086004 GO:1901844 GO:1901898 GO:1902514 GO:1990266
Q13370	PDE3B	Homo sapiens (human)	9606	2	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity G protein-coupled receptor signaling pathway Golgi apparatus angiogenesis cAMP-mediated signaling cGMP-inhibited cyclic-nucleotide phosphodiesterase activity calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity cellular response to insulin stimulus cytosol endoplasmic reticulum guanyl-nucleotide exchange factor complex membrane metal ion binding negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of angiogenesis negative regulation of cell adhesion mediated by integrin negative regulation of cell adhesion negative regulation of lipid catabolic process protein kinase B binding regulation of angiogenesis regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	GO:0001525 GO:0004114 GO:0004115 GO:0004119 GO:0005783 GO:0005794 GO:0005829 GO:0007162 GO:0007186 GO:0016020 GO:0016525 GO:0019933 GO:0032045 GO:0032869 GO:0033629 GO:0043422 GO:0045765 GO:0046872 GO:0047555 GO:0048101 GO:0050995 GO:0051896 GO:0106072
Q14432	PDE3A	Homo sapiens (human)	9606	7	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity G protein-coupled receptor signaling pathway apoptotic signaling pathway cAMP-mediated signaling cGMP-inhibited cyclic-nucleotide phosphodiesterase activity cGMP-mediated signaling calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity cellular response to cGMP cellular response to transforming growth factor beta stimulus cytosol estrogen binding lipid metabolic process membrane metal ion binding negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of apoptotic process negative regulation of cAMP-mediated signaling negative regulation of vascular permeability nuclear estrogen receptor activity oocyte maturation positive regulation of oocyte development positive regulation of vascular permeability regulation of meiotic nuclear division regulation of ribonuclease activity response to xenobiotic stimulus	GO:0001556 GO:0004114 GO:0004115 GO:0004119 GO:0005829 GO:0006629 GO:0007186 GO:0009410 GO:0016020 GO:0019933 GO:0019934 GO:0030284 GO:0040020 GO:0043066 GO:0043116 GO:0043117 GO:0043951 GO:0046872 GO:0047555 GO:0048101 GO:0060282 GO:0060700 GO:0071321 GO:0071560 GO:0097190 GO:0099130 GO:0106072
O76083	PDE9A	Homo sapiens (human)	9606	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity Golgi apparatus cAMP-mediated signaling cGMP catabolic process cGMP metabolic process cytosol endoplasmic reticulum identical protein binding metal ion binding negative regulation of neural precursor cell proliferation nucleoplasm perikaryon perinuclear region of cytoplasm plasma membrane positive regulation of cardiac muscle hypertrophy positive regulation of long-term synaptic potentiation ruffle membrane sarcolemma signal transduction	GO:0004114 GO:0004115 GO:0005654 GO:0005783 GO:0005794 GO:0005829 GO:0005886 GO:0007165 GO:0010613 GO:0019933 GO:0032587 GO:0042383 GO:0042802 GO:0043204 GO:0046068 GO:0046069 GO:0046872 GO:0047555 GO:0048471 GO:1900273 GO:2000178
P12019	pdsA pde1 pdeA	Dictyostelium discoideum	44689	3	0	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cAMP binding cAMP catabolic process cGMP binding cell surface endoplasmic reticulum extracellular region extracellular regulation of signal transduction negative regulation of glucose mediated signaling pathway plasma membrane response to cAMP response to catechin response to differentiation-inducing factor 1 response to dithiothreitol slug development involved in sorocarp development	GO:0004114 GO:0004115 GO:0005576 GO:0005783 GO:0005886 GO:0006198 GO:0007193 GO:0009986 GO:0030552 GO:0030553 GO:0031152 GO:0031153 GO:0047555 GO:0051591 GO:0072720 GO:1900115 GO:1902168 GO:1902660 GO:1903013
Q8CA95	Pde10a	Mus musculus (house mouse)	10090	2	3	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity cAMP binding cAMP catabolic process cAMP-mediated signaling cGMP binding cGMP catabolic process cGMP-stimulated cyclic-nucleotide phosphodiesterase activity cyclic-nucleotide phosphodiesterase activity cytosol metal ion binding negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling neuronal cell body perikaryon regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of protein kinase A signaling	GO:0004112 GO:0004114 GO:0004115 GO:0004118 GO:0005829 GO:0006198 GO:0010738 GO:0010754 GO:0019933 GO:0030552 GO:0030553 GO:0043025 GO:0043204 GO:0043951 GO:0046069 GO:0046872 GO:0047555 GO:0106070
Q9Y233	PDE10A	Homo sapiens (human)	9606	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity cAMP binding cAMP catabolic process cAMP-mediated signaling cGMP binding cGMP catabolic process cGMP-stimulated cyclic-nucleotide phosphodiesterase activity cytosol metal ion binding negative regulation of cGMP-mediated signaling	GO:0004114 GO:0004115 GO:0004118 GO:0005829 GO:0006198 GO:0010754 GO:0019933 GO:0030552 GO:0030553 GO:0046069 GO:0046872 GO:0047555
Q8IKD3	PDEdelta PDE4	Plasmodium falciparum 3D7	36329	1	0	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity cAMP binding cAMP-mediated signaling cGMP catabolic process cyclic nucleotide metabolic process gamete generation membrane metal ion binding	GO:0004114 GO:0004115 GO:0007276 GO:0009187 GO:0016020 GO:0019933 GO:0030552 GO:0046069 GO:0046872 GO:0047555
Q9HCR9	PDE11A	Homo sapiens (human)	9606	1	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity cAMP-mediated signaling cGMP binding cGMP-stimulated cyclic-nucleotide phosphodiesterase activity cyclic-nucleotide phosphodiesterase activity cytosol metabolic process metal ion binding negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling signal transduction	GO:0004112 GO:0004114 GO:0004115 GO:0004118 GO:0005829 GO:0007165 GO:0008152 GO:0010754 GO:0019933 GO:0030553 GO:0043951 GO:0046872 GO:0047555
Q922S4	Pde2a	Mus musculus (house mouse)	10090	2	3	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity GAF domain binding Golgi apparatus aorta development axon cAMP binding cAMP-mediated signaling cGMP binding cGMP catabolic process cGMP-mediated signaling cGMP-stimulated cyclic-nucleotide phosphodiesterase activity cardiac septum development cellular response to cGMP cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to lipopolysaccharide cellular response to macrophage colony-stimulating factor stimulus cellular response to mechanical stimulus coronary vasculature development cytoplasm cytosol dendrite endoplasmic reticulum establishment of endothelial barrier heart development heart valve development hippocampal mossy fiber identical protein binding intracellular signal transduction metal ion binding mitochondrial inner membrane mitochondrial matrix mitochondrial outer membrane mitochondrion negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling negative regulation of oxidative phosphorylation negative regulation of transcription by RNA polymerase II negative regulation of vascular permeability nucleus perinuclear region of cytoplasm plasma membrane positive regulation of gene expression positive regulation of inflammatory response positive regulation of vascular permeability presynaptic membrane protein homodimerization activity regulation of cAMP-mediated signaling regulation of mitochondrion organization regulation of nitric oxide mediated signal transduction synaptic membrane ventricular septum development	GO:0000122 GO:0003170 GO:0003279 GO:0003281 GO:0004115 GO:0004118 GO:0005634 GO:0005737 GO:0005739 GO:0005741 GO:0005743 GO:0005759 GO:0005783 GO:0005794 GO:0005829 GO:0005886 GO:0007507 GO:0010628 GO:0010749 GO:0010754 GO:0010821 GO:0019933 GO:0019934 GO:0030424 GO:0030425 GO:0030552 GO:0030553 GO:0035556 GO:0035904 GO:0036004 GO:0036006 GO:0042734 GO:0042802 GO:0042803 GO:0043116 GO:0043117 GO:0043949 GO:0043951 GO:0046069 GO:0046872 GO:0047555 GO:0048471 GO:0050729 GO:0060976 GO:0061028 GO:0071222 GO:0071260 GO:0071321 GO:0090324 GO:0097011 GO:0097060 GO:0097457 GO:0106072
O00408	PDE2A	Homo sapiens (human)	9606	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity Golgi apparatus TPR domain binding adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway aorta development cAMP binding cAMP-mediated signaling cGMP binding cGMP catabolic process cGMP-mediated signaling cGMP-stimulated cyclic-nucleotide phosphodiesterase activity cellular response to 2,3,7,8-tetrachlorodibenzodioxine cellular response to cAMP cellular response to cGMP cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to macrophage colony-stimulating factor stimulus cellular response to mechanical stimulus cellular response to transforming growth factor beta stimulus cellular response to xenobiotic stimulus cytoplasm cytosol endoplasmic reticulum establishment of endothelial barrier heart valve development identical protein binding magnesium ion binding mitochondrial inner membrane mitochondrial matrix mitochondrial outer membrane monocyte differentiation negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of cAMP-mediated signaling negative regulation of cGMP-mediated signaling negative regulation of transcription by RNA polymerase II negative regulation of vascular permeability nucleus perinuclear region of cytoplasm phosphate ion binding plasma membrane positive regulation of gene expression positive regulation of inflammatory response positive regulation of vascular permeability presynaptic membrane protein homodimerization activity regulation of cAMP-mediated signaling regulation of cGMP-mediated signaling regulation of mitochondrion organization synaptic membrane ventricular septum development zinc ion binding	GO:0000122 GO:0000287 GO:0003170 GO:0003281 GO:0004115 GO:0004118 GO:0005634 GO:0005737 GO:0005741 GO:0005743 GO:0005759 GO:0005783 GO:0005794 GO:0005829 GO:0005886 GO:0007193 GO:0008270 GO:0010628 GO:0010752 GO:0010754 GO:0010821 GO:0019933 GO:0019934 GO:0030224 GO:0030552 GO:0030553 GO:0030911 GO:0035904 GO:0036006 GO:0042301 GO:0042734 GO:0042802 GO:0042803 GO:0043116 GO:0043117 GO:0043949 GO:0043951 GO:0046069 GO:0047555 GO:0048471 GO:0050729 GO:0061028 GO:0071260 GO:0071320 GO:0071321 GO:0071466 GO:0071560 GO:0097011 GO:0097060 GO:0106072 GO:1904613
Q07343	PDE4B DPDE4	Homo sapiens (human)	9606	2	2	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity T cell receptor signaling pathway Z disc cAMP binding cAMP catabolic process cAMP-mediated signaling calcium channel regulator activity cellular response to epinephrine stimulus cellular response to lipopolysaccharide cellular response to xenobiotic stimulus centrosome cytosol dendritic spine excitatory synapse gamma-tubulin binding gamma-tubulin complex leukocyte migration metal ion binding negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway negative regulation of relaxation of cardiac muscle neutrophil chemotaxis neutrophil homeostasis nucleus perinuclear region of cytoplasm positive regulation of interleukin-2 production positive regulation of type II interferon production postsynaptic density regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of cardiac muscle cell contraction synaptic vesicle transmembrane transporter binding voltage-gated calcium channel complex	GO:0000930 GO:0001780 GO:0004115 GO:0005246 GO:0005634 GO:0005813 GO:0005829 GO:0005891 GO:0006198 GO:0008021 GO:0014069 GO:0019933 GO:0030018 GO:0030552 GO:0030593 GO:0032729 GO:0032743 GO:0043015 GO:0043197 GO:0044325 GO:0046872 GO:0047555 GO:0048471 GO:0050852 GO:0050900 GO:0060076 GO:0071222 GO:0071466 GO:0071872 GO:0071878 GO:0086004 GO:1901898 GO:1902514
Q9W4T4	dnc	Drosophila melanogaster (fruit fly)	7227	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity anesthesia-resistant memory associative learning axon extension behavioral response to ethanol cAMP catabolic process cAMP-mediated signaling chemical synaptic transmission circadian rhythm conditioned taste aversion courtship behavior cytosol learning mating behavior medium-term memory memory metal ion binding negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway nonassociative learning nucleus olfactory learning perinuclear region of cytoplasm regulation of protein kinase A signaling short-term memory synapse thermosensory behavior	GO:0001661 GO:0004115 GO:0005634 GO:0005829 GO:0006198 GO:0007268 GO:0007612 GO:0007613 GO:0007614 GO:0007615 GO:0007617 GO:0007619 GO:0007623 GO:0008306 GO:0008355 GO:0010738 GO:0019933 GO:0040040 GO:0045202 GO:0046872 GO:0046958 GO:0047555 GO:0048149 GO:0048471 GO:0048675 GO:0072375 GO:0106072
P12252	dnc	Drosophila melanogaster (fruit fly)	7227	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity anesthesia-resistant memory associative learning axon extension cAMP catabolic process cAMP-mediated signaling chemical synaptic transmission circadian rhythm conditioned taste aversion courtship behavior cytosol learning mating behavior memory metal ion binding nonassociative learning nucleus olfactory learning perinuclear region of cytoplasm regulation of protein kinase A signaling short-term memory synapse thermosensory behavior	GO:0001661 GO:0004115 GO:0005634 GO:0005829 GO:0006198 GO:0007268 GO:0007612 GO:0007613 GO:0007614 GO:0007615 GO:0007617 GO:0007619 GO:0007623 GO:0008306 GO:0008355 GO:0010738 GO:0019933 GO:0040040 GO:0045202 GO:0046872 GO:0046958 GO:0047555 GO:0048471 GO:0048675
Q86H13	Pde4	Dictyostelium discoideum	44689	23	0	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cAMP binding cAMP-mediated signaling extracellular region metal ion binding plasma membrane response to caffeine sorocarp development	GO:0004115 GO:0005576 GO:0005886 GO:0019933 GO:0030552 GO:0030587 GO:0031000 GO:0046872 GO:0047555
Q8I6Z7	PDEbeta PDE2	Plasmodium falciparum 3D7	36329	1	0	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cAMP catabolic process cAMP-mediated signaling cGMP catabolic process calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity endoplasmic reticulum membrane metal ion binding negative regulation of cAMP-mediated signaling plasma membrane signal transduction	GO:0004115 GO:0004117 GO:0005789 GO:0005886 GO:0006198 GO:0007165 GO:0019933 GO:0043951 GO:0046069 GO:0046872 GO:0047555
Q08493	PDE4C DPDE1	Homo sapiens (human)	9606	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cAMP catabolic process cAMP-mediated signaling cilium cytosol extracellular space metal ion binding nucleus perinuclear region of cytoplasm	GO:0004115 GO:0005615 GO:0005634 GO:0005829 GO:0005929 GO:0006198 GO:0019933 GO:0046872 GO:0047555 GO:0048471
Q4CQR0	Tc00.1047053509943.20	Trypanosoma cruzi strain CL Brener	353153	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cAMP-mediated signaling cGMP catabolic process metal ion binding	GO:0004115 GO:0019933 GO:0046069 GO:0046872 GO:0047555
Q49UB9	C3747_204g30	Trypanosoma cruzi	5693	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cAMP-mediated signaling cGMP catabolic process metal ion binding	GO:0004115 GO:0019933 GO:0046069 GO:0046872 GO:0047555
Q14123	PDE1C	Homo sapiens (human)	9606	0	1	3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-GMP phosphodiesterase activity cAMP-mediated signaling calmodulin binding calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity cytosol lysosome metal ion binding neuronal cell body	GO:0004115 GO:0004117 GO:0005516 GO:0005764 GO:0005829 GO:0019933 GO:0043025 GO:0046872 GO:0047555 GO:0048101

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