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Dual specificity mitogen-activated protein kinase kinase 1
Summary
- UniProt ID
- P31938
- Gene Symbol
-
- Map2k1
- Mek1
- Prkmk1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003563
- GlyGen
- P31938
- PubChem
- P31938
- The O-GlcNAc Database
- P31938
- RaftProt
- P31938
Annotation
- Keyword
-
- ATP-binding
- Cytoskeleton
- Direct protein sequencing
- Membrane
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| labyrinthine layer development |
| regulation of Golgi inheritance |
| positive regulation of endodermal cell differentiation |
| regulation of axon regeneration |
| regulation of early endosome to late endosome transport |
| GO Term |
|---|
| nucleus |
| perikaryon |
| mitochondrion |
| cytosol |
| endoplasmic reticulum |
| centrosome |
| early endosome |
| late endosome |
| focal adhesion |
| postsynaptic density |
| GO Term |
|---|
| protein kinase binding |
| protein serine/threonine kinase activator activity |
| mitogen-activated protein kinase kinase kinase binding |
Sequence
MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAASI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 21 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Frs2-mediated activation | Mus musculus |
| MAP2K and MAPK activation | Mus musculus |
| MAPK3 (ERK1) activation | Mus musculus |
| Negative feedback regulation of MAPK pathway | Mus musculus |
| RAF activation | Mus musculus |
| Signal transduction by L1 | Mus musculus |
