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Dual specificity mitogen-activated protein kinase kinase 4
Summary
- UniProt ID
- P47809
- Gene Symbol
-
- Map2k4
- Jnkk1
- Mek4
- Mkk4
- Prkmk4
- Sek1
- Serk1
- Skk1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003634
- GlyGen
- P47809
- PubChem
- P47809
- The O-GlcNAc Database
- P47809
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Apoptosis
- Cytoplasm
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Stress response
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of protein phosphorylation |
| MAPK cascade |
| JNK cascade |
| intrinsic apoptotic signaling pathway in response to hydrogen peroxide |
| cellular response to mechanical stimulus |
| cellular response to sorbitol |
| GO Term |
|---|
| axon |
| dendrite cytoplasm |
| perikaryon |
| cytosol |
| nucleus |
Sequence
MAAPSPSGGGGSGGGGGTPGPIGPPASGHPAVSSMQGKRKALKLNFANPPVKSTARFTLNPNTTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 62 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FCERI mediated MAPK activation | Mus musculus |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | Mus musculus |
| Oxidative Stress Induced Senescence | Mus musculus |
