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Lysosomal acid glucosylceramidase

Summary

UniProt ID

P17439

Gene Symbol

Gba1
Gba

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003442

GlyConnect

2339

GlyGen

P17439

PubChem

P17439

SwissLipids

SLP:000001930

RaftProt

P17439

Annotation

Keyword

Cholesterol metabolism
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosidase
Glycosyltransferase
Lysosome
Membrane
Reference proteome
Signal
Sphingolipid metabolism

Gene Ontology (GO)

Displaying entries **1 - 10** of 56 in total

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GO Term
autophagy
nervous system process
regulation of protein metabolic process
skin epidermis development
positive regulation of proteolysis involved in protein catabolic process
autophagosome organization
microglia differentiation
cerebellar Purkinje cell layer formation
pyramidal neuron differentiation
negative regulation of protein-containing complex assembly

Displaying **all 7** entries
GO Term
endoplasmic reticulum
trans-Golgi network
extracellular space
lysosome
lysosomal membrane
Golgi apparatus
lysosomal lumen

Displaying **all 8** entries
GO Term
steryl-beta-glucosidase activity
galactosylceramidase activity
glucosylceramidase activity
beta-glucosidase activity
glucosyltransferase activity
scavenger receptor binding
signaling receptor binding
hydrolase activity

Annotation information from UniProt.

Sequence

MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine		UniProt GlyGen
78	N-linked (GlcNAc...) asparagine	G74724QE G53434XO	GlycoProtDB UniProt GlyGen GlyConnect
165	N-linked (GlcNAc...) (high mannose) asparagine	G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
289	N-linked (GlcNAc...) asparagine	G83460ZZ G39188ZX G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
480	N-linked (GlcNAc...) asparagine		UniProt GlyGen