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Serine/threonine-protein kinase PAK 2

Summary

UniProt ID

Q8CIN4

Gene Symbol

Pak2

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0006682
PubChem: Q8CIN4

Annotation

Keyword

ATP-binding
Acetylation
Allosteric enzyme
Apoptosis
Cytoplasm
Growth regulation
Lipoprotein
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
negative regulation of apoptotic process
cardiac muscle hypertrophy
adherens junction assembly
regulation of axonogenesis
dendritic spine development
cellular response to organic cyclic compound
cellular response to transforming growth factor beta stimulus
protein localization to cell-cell junction
positive regulation of extrinsic apoptotic signaling pathway
regulation of MAPK cascade

Displaying **all 9** entries
GO Term
cytosol
perinuclear region of cytoplasm
nucleus
cytoplasm
cell-cell junction
membrane
secretory granule
postsynaptic density
glutamatergic synapse

Displaying **all 8** entries
GO Term
protein tyrosine kinase activator activity
protein kinase activity
protein serine/threonine kinase activity
ATP binding
protein kinase binding
identical protein binding
protein serine kinase activity
small GTPase binding

Annotation information from UniProt.

Sequence

MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRNKIISIFSGTEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTKGSETSAVVTEEDDDDEDAAPPVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
110				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 19 in total

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Pathway Name	Organism
CD209 (DC-SIGN) signaling	Mus musculus
CD28 dependent Vav1 pathway	Mus musculus
Ephrin signaling	Mus musculus
FCERI mediated MAPK activation	Mus musculus
Generation of second messenger molecules	Mus musculus
MAPK6/MAPK4 signaling	Mus musculus
RAC1 GTPase cycle	Mus musculus
RAC2 GTPase cycle	Mus musculus
RAC3 GTPase cycle	Mus musculus
RHO GTPases activate PAKs	Mus musculus