GlyCosmos Portal

Canis familiaris (dog)

Summary

Taxonomy ID: 9615
PubChem Taxonomy: 9615

Genes (1435) Glycans (57) Glycoproteins (513) Lectins (17) Pathways (270)

Displaying entries **51 - 75** of **270** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Passive transport by Aquaporins	Aquaporin 10 Aquaporin 12 Aquaporin 8 Aquaporin 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin Lens fiber major intrinsic protein Uncharacterized protein	A0A8I3MCV0 A0A8I3N7P7 A0A8I3NP65 A0A8I3NT67 A0A8I3P6A6 A0A8I3P7C5 A0A8I3PD19 A0A8I3PFQ0 A0A8I3QCN1 A0A8I3S111 A2IBY8 Q9N2J4	AQP0 AQP1 AQP10 AQP11 AQP12 AQP2 AQP3 AQP4 AQP6 AQP7 AQP8 AQP9 MIP
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Solute carrier family 25 member 16 Solute carrier family 5 member 6	A0A8I3MUX5 A0A8I3MVX3 A0A8I3MY61 A0A8I3PCZ1 A0A8I3Q2U7 A0A8I3RQN4 A0A8I3S3J2 Q9TSX8	AASDHPPT FASN PANK4 PDZD11 SLC25A16 SLC25A42 SLC5A6 VNN1
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Procathepsin L Serpin family B member 13	A0A8I3MMH2 Q9GL24	CTSL CTSL1 SERPINB13
Stimuli-sensing channels	Acid sensing ion channel subunit 1 Acid sensing ion channel subunit 2 Acid sensing ion channel subunit 3 Acid sensing ion channel subunit family member 4 Acid sensing ion channel subunit family member 5 Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Aspartate beta-hydroxylase Barttin CLCNK type accessory subunit beta Bestrophin Bestrophin Bestrophin Bestrophin Calcium-activated chloride channel regulator 1 Chloride channel accessory 2 Chloride channel accessory 4 Chloride channel protein 1 Chloride channel protein 2 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Chloride intracellular channel protein E3 ubiquitin-protein ligase EF-hand domain-containing protein HECT-type E3 ubiquitin transferase Osteoclastogenesis associated transmembrane protein 1 Protein tweety homolog Protein tweety homolog Protein tweety homolog RAF proto-oncogene serine/threonine-protein kinase Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Serine/threonine-protein kinase Sgk1 Serum/glucocorticoid regulated kinase family, member 3 Sodium channel epithelial 1 subunit delta Sodium leak channel, non-selective Solute carrier family 17 member 3 Solute carrier family 9 member B1 Solute carrier family 9 member B2 Solute carrier family 9 member C2 (putative) Sorcin Stomatin like 3 Stomatin Triadin Two pore segment channel 1 Two pore segment channel 2 Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Unc-79 homolog, NALCN channel complex subunit Unc-80 homolog, NALCN channel complex subunit peptidylprolyl isomerase	A0A8I3M9N6 A0A8I3MIG8 A0A8I3MK25 A0A8I3MKE6 A0A8I3MKT6 A0A8I3MMN5 A0A8I3MSQ7 A0A8I3MT21 A0A8I3MUX4 A0A8I3MXS3 A0A8I3N0C5 A0A8I3N0E7 A0A8I3N106 A0A8I3N6S0 A0A8I3N726 A0A8I3NAC3 A0A8I3NFB9 A0A8I3NH80 A0A8I3NHZ8 A0A8I3NKC4 A0A8I3NSX7 A0A8I3NUI9 A0A8I3NXW9 A0A8I3NYL1 A0A8I3P370 A0A8I3P4T9 A0A8I3P560 A0A8I3P659 A0A8I3P6A5 A0A8I3P7M3 A0A8I3P948 A0A8I3PAS7 A0A8I3PCD4 A0A8I3PDN2 A0A8I3PET1 A0A8I3PGN5 A0A8I3PJ01 A0A8I3PJ21 A0A8I3PJD4 A0A8I3PNF9 A0A8I3PP54 A0A8I3PRH5 A0A8I3PSM5 A0A8I3PV66 A0A8I3PY43 A0A8I3PZA0 A0A8I3Q0B9 A0A8I3Q0M9 A0A8I3Q2P4 A0A8I3Q383 A0A8I3Q4Q6 A0A8I3Q679 A0A8I3Q886 A0A8I3Q8P6 A0A8I3Q8R4 A0A8I3QA03 A0A8I3QXX9 A0A8I3QYD0 A0A8I3RQJ2 A0A8I3RSF1 A0A8I3RW06 A0A8I3RY81 A0A8I3RZ58 A0A8I3S651 A0A8I3SA78 P63050 Q9MZT1	ANO1 ANO2 ANO3 ANO4 ANO5 ANO6 ANO7 ANO8 ANO9 ASIC1 ASIC2 ASIC3 ASIC4 ASIC5 ASPH BEST1 BEST2 BEST3 BEST4 BSND CALM2 CLCA1 CLCA2 CLCA4 CLCN1 CLCN2 CLCN4 CLCN5 CLCN6 CLCN7 CLCNK CLCNKA CLIC2 LOC119880472 NALCN NEDD4L OSTM1 RAF1 RPS27A RYR1 RYR2 RYR3 SCNN1A SCNN1B SCNN1D SCNN1G SGK1 SGK3 SLC17A2 SLC9B1 SLC9B2 SLC9C2 SRI STOM STOML3 TPCN1 TPCN2 TRDN TTYH1 TTYH2 TTYH3 UBA52 UBB UBC UBCEP2 UNC79 UNC80 WWP1
Role of phospholipids in phagocytosis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 5'-3' exonuclease PLD3 Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Phospholipase Phospholipase Phospholipid phosphatase 4 Protein kinase C delta type Protein kinase C epsilon type T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phospholipase A2	A0A5F4C2B1 A0A8I3MFY1 A0A8I3MMY6 A0A8I3MQR0 A0A8I3MV98 A0A8I3N971 A0A8I3NEM6 A0A8I3NWR3 A0A8I3NYY2 A0A8I3NZG2 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PAT0 A0A8I3PCM7 A0A8I3PD67 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PWT0 A0A8I3PWT3 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3PZJ7 A0A8I3Q258 A0A8I3Q590 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QHH1 A0A8I3QQ00 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S3N2 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 A0A8I3SCI7 E2RP87	CD247 CD3G FCGR1A FCGR2B FCGR3A LOC478984 PIK3CA PIK3CB PIK3R1 PIK3R2 PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPP4 PLPP5 PRKCD PRKCE SYK
Ion homeostasis	ATP binding cassette subfamily C member 9 ATP-sensitive inward rectifier potassium channel 11 ATPase Na+/K+ transporting subunit alpha 3 Adenosylhomocysteinase like 1 Aspartate beta-hydroxylase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban Chloride intracellular channel protein EF-hand domain-containing protein FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Nitric oxide synthase 1 Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 8 member A2 Solute carrier family 8 member A3 Sorcin Stromal interaction molecule 1 Triadin Troponin I, cardiac muscle cAMP-dependent protein kinase catalytic subunit alpha calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase peptidylprolyl isomerase	A0A8I3M9N6 A0A8I3MFG9 A0A8I3MID3 A0A8I3MJQ7 A0A8I3MK29 A0A8I3MM26 A0A8I3MQA1 A0A8I3MRH3 A0A8I3MSQ7 A0A8I3MSS1 A0A8I3MT21 A0A8I3MTJ5 A0A8I3MXS3 A0A8I3NIS8 A0A8I3NKB2 A0A8I3NMP2 A0A8I3NNW7 A0A8I3NVA4 A0A8I3NYA8 A0A8I3P560 A0A8I3PCD4 A0A8I3PEN3 A0A8I3PJ46 A0A8I3PQA5 A0A8I3PRW9 A0A8I3PT17 A0A8I3PW88 A0A8I3PX80 A0A8I3Q281 A0A8I3Q2P2 A0A8I3Q886 A0A8I3Q8P6 A0A8I3QAS6 A0A8I3RSR2 A0A8I3RTF4 A0A8I3RVD4 A0A8I3RWC7 A0A8I3RWM0 A0A8I3RY81 A0A8I3S0A4 A0A8I3SBE1 A0A8I3SBK9 O46674 P23685 P61012 Q8MKD5	ABCC9 AHCYL1 ASPH ATP1A1 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM2 CAMK2A CAMK2B CAMK2G CLIC2 FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 ITPR1 ITPR2 ITPR3 KCNJ11 LOC119880472 NCX1 NOS1 PLN PRKACA RYR1 RYR2 RYR3 SLC8A1 SLC8A2 SLC8A3 SRI STIM1 TNNI3 TRDN TRPC1
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GRB2 associated binding protein 1 GRB2 associated binding protein 2 Glial cell derived neurotrophic factor Growth factor receptor bound protein 10 Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Protein kinase C RAP1 GTPase activating protein Ret proto-onco SH3 and multiple ankyrin repeat domains 3 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MGQ2 A0A8I3MHB6 A0A8I3MNH7 A0A8I3MVS5 A0A8I3N0M1 A0A8I3N7X4 A0A8I3N8L0 A0A8I3N971 A0A8I3N9M7 A0A8I3NBK6 A0A8I3NID0 A0A8I3NUU1 A0A8I3NXI8 A0A8I3P1P0 A0A8I3P4L9 A0A8I3P519 A0A8I3P721 A0A8I3PIF6 A0A8I3PMT9 A0A8I3PQ79 A0A8I3PRW9 A0A8I3PT69 A0A8I3PUQ8 A0A8I3PW06 A0A8I3PWT3 A0A8I3Q1A9 A0A8I3Q244 A0A8I3Q525 A0A8I3QCB4 A0A8I3QHK6 A0A8I3S0I1 A0A8I3S0X9 A0A8I3S3D9 A0A8I3S3N2 A0A8I3SBF9 A0A8I3SCI7 E2R534	DBN1 DOK1 DOK2 DOK4 DOK5 DOK6 FRS2 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA4 GRB10 GRB2 GRB7 IRS2 LOC100856339 MAPK7 NRTN PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PLCG1 PRKACA PRKACB PRKCA PSPN PTPN11 RAP1GAP RET SHANK3 SHC1 SHC3 SOS1 SRC
Interleukin-4 and Interleukin-13 signaling	Endoplasmin Interleukin 13 receptor subunit alpha 1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-4 receptor subunit alpha Interleukin-4 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Suppressor of cytokine signaling 5 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I3MUC6 A0A8I3NVH4 A0A8I3PDX4 A0A8I3PSA1 A0A8I3RS40 A0A8I3RV66 A0A8I3RXB9 A0A8I3S4Z2 A0A8I3S6B0 A0A8I3SBB2 O77762 P41148 Q95LF0 Q9N0W9	GRP94 HSP90B1 HSPC4 IL13 IL13RA1 IL13RA2 IL4 IL4R JAK1 JAK2 JAK3 SOCS5 STAT1 STAT3 STAT6 TRA1 TYK2
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1
Hydrolysis of LPC	Lysosomal phospholipase A and acyltransferase Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like	A0A8I3MZB9 A0A8I3P3G6 A0A8I3P464 A0A8I3PKA9 A0A8I3QXI0 A0A8I3RZX3 Q6XPZ3	LYPLA3 PLA2G15 PLA2G4A PLA2G4B PLA2G4D PLA2G4E PLA2G4F PLBD1
Creatine metabolism	Creatine kinase B-type Creatine kinase M-type Creatine kinase S-type, mitochondrial Creatine kinase U-type, mitochondrial Glycine amidinotransferase Sodium- and chloride-dependent betaine transporter Transporter Transporter Transporter guanidinoacetate N-methyltransferase	A0A8I3N7M6 A0A8I3NN25 A0A8I3PNS0 A0A8I3QPK3 A0A8I3RV00 A0A8I3S431 A0A8I3S958 P05123 P05124 P27799	CKB CKM CKMT2 GAMT GATM LOC478277 SLC6A11 SLC6A12 SLC6A7 SLC6A8
Downstream TCR signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 ADRM1 26S proteasome ubiquitin receptor BCL10 immune signaling adaptor Caspase recruitment domain family member 11 Cullin 1 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme F-box and WD repeat domain containing 11 Ig-like domain-containing protein IkappaB kinase Immunoglobulin V-set domain-containing protein Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein kinase C RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha variable 29/delta variable 5 T cell receptor associated transmembrane adaptor 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ82 A0A8I3MKK6 A0A8I3MKL4 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MNA4 A0A8I3MNI0 A0A8I3MQX7 A0A8I3MR89 A0A8I3MV98 A0A8I3MZ69 A0A8I3N0P1 A0A8I3N165 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N7L6 A0A8I3N971 A0A8I3N9G3 A0A8I3NAC6 A0A8I3NFB9 A0A8I3NH42 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NT57 A0A8I3NT75 A0A8I3NTK0 A0A8I3NUC6 A0A8I3NW81 A0A8I3NXK9 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4A1 A0A8I3P4Z1 A0A8I3P564 A0A8I3P6I7 A0A8I3PAB8 A0A8I3PAP4 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PFI5 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PR42 A0A8I3PWT3 A0A8I3PZT2 A0A8I3QV78 A0A8I3QYD0 A0A8I3RR14 A0A8I3RRK6 A0A8I3RRL7 A0A8I3RRR7 A0A8I3RT39 A0A8I3RXV3 A0A8I3RZD9 A0A8I3S023 A0A8I3S1Z6 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S3N2 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P27597 P33705 P60483 P63050 Q6F3J0	ADRM1 BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CDC34 CHUK CUL1 DLA-DQA1 DLA-DRA FBXW11 HLA-DQB2 IKBKB IKBKG INPP5D LCK LOC100686569 LOC100687259 LOC119881719 MALT1 MAP3K7 MMAC1 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKCQ PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMB1 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN RELA RIPK2 RPS27A SKP1 TAB2 TRAF6 TRAT1 TRAV29DV5 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2N
Amine ligand-binding receptors	G protein-coupled receptor 143	A0A8I3PL97	GPR143
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma CD101 molecule Cytoplasmic protein FYN binding protein 1 GRB2 related adaptor protein 2 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Lymphocyte cytosolic protein 2 MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Phosphoinositide phospholipase C T cell receptor alpha variable 29/delta variable 5 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I3MED5 A0A8I3MFY1 A0A8I3MGV8 A0A8I3MJ11 A0A8I3MKK6 A0A8I3MMK2 A0A8I3MMK3 A0A8I3MMZ1 A0A8I3MV98 A0A8I3MZ69 A0A8I3NAC6 A0A8I3NMF7 A0A8I3NTK0 A0A8I3NZG2 A0A8I3P4A1 A0A8I3P564 A0A8I3P6Q8 A0A8I3P8U2 A0A8I3PAB8 A0A8I3PNN9 A0A8I3Q5D2 A0A8I3QD39 A0A8I3S023 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S602 A0A8I3SCI7 P27597 P33705	CD101 CD247 CD3D CD3E CD3G CD4 DLA-DQA1 DLA-DRA FYB1 GRAP2 HLA-DQB2 ITK LAT LCK LCP2 NCK1 PAK1 PAK2 PAK3 PLCG1 PLCG2 TRAV29DV5 ZAP70
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty related EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2 Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MXL0 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NYK3 A0A8I3PJY6 A0A8I3PWQ1 A0A8I3S5D3 A0A8I3SAY5 J9P3I7 Q20FD0	FGF10 FGF17 FGF18 FGF22 FGF23 FGF3 FGF3A FGF4 FGF5 FGF7A FGF8 FGF8B FGFRL1 SPRED1 SPRED2
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	B cell linker B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD19 molecule CD79a molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides 1 Growth factor receptor bound protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase adaptor protein 1 SH3 domain containing kinase binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Stromal interaction molecule 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A8I3MIL9 A0A8I3MPF4 A0A8I3MUW4 A0A8I3N971 A0A8I3NA65 A0A8I3NKB2 A0A8I3NVL7 A0A8I3NWR3 A0A8I3NZG2 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P501 A0A8I3P6V2 A0A8I3P7Z3 A0A8I3P941 A0A8I3PD67 A0A8I3PDA6 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PT69 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PW88 A0A8I3PWC6 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PY14 A0A8I3PYF1 A0A8I3Q1C3 A0A8I3Q281 A0A8I3Q2P2 A0A8I3Q525 A0A8I3Q5C2 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RWM0 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S3D9 A0A8I3S602 A0A8I3S6H5 A0A8I3S960 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P0CAN6	BLNK BTK CD19 CD79A CD79B DAPP1 GRB2 IGHM ITPR1 ITPR2 ITPR3 MAG NCK1 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTPN6 SH3KBP1 SOS1 STIM1 SYK TRPC1 VAV1
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Toll-like receptor 9 Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MWD3 A0A8I3N971 A0A8I3N9M7 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWT3 A0A8I3Q7B4 A0A8I3QFN1 A0A8I3RTN7 A0A8I3S0I1 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0 Q5I2M8	FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 GAB1 GAB2 GRB2 IRS1 IRS2 KGF KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9
Transport of RCbl within the body	ATP binding cassette subfamily D member 4 CD320 molecule LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Lysosomal cobalamin transport escort protein LMBD1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Transcobalamin-2 Transcobalamin-like C-terminal domain-containing protein	A0A8I3N1I8 A0A8I3N584 A0A8I3NS16 A0A8I3P9U6 A0A8I3PAV5 A0A8I3PKW5 A0A8I3Q758 A0A8I3S4Z0 Q6UR05	ABCC1 CD320 LDLRAP1 LMBRD1 LOC119869278 LRP2 MRP1 TCN1 TCN2
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide	A0A8I3PCA6 A0A8I3PCK7 A0A8I3RSX8 Q9GLF6 Q9TUP7	HCRT HCRTR1 HCRTR2 OX PPOX QRFP QRFPR
Reduction of cytosolic Ca++ levels	Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase EF-hand domain-containing protein Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sodium/calcium exchanger 1 Solute carrier family 8 member A2 Solute carrier family 8 member A3 Sorcin	A0A8I3MJQ7 A0A8I3MSQ7 A0A8I3MTJ5 A0A8I3NYA8 A0A8I3PEN3 A0A8I3PJ46 A0A8I3RTF4 A0A8I3RVD4 A0A8I3RY81 A0A8I3S0A4 O46674 P23685	ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM2 NCX1 SLC8A1 SLC8A2 SLC8A3 SRI
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Gamma-glutamyltransferase 6 Glutathione S-transferase Glutathione S-transferase Glutathione hydrolase Glutathione hydrolase Glutathione transferase Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 N-acyl-aliphatic-L-amino acid amidohydrolase Sulfotransferase 1A1 Sulfotransferase Sulfotransferase glucuronosyltransferase glucuronosyltransferase glucuronosyltransferase	A0A8I3MEU4 A0A8I3MEX7 A0A8I3N072 A0A8I3N1I8 A0A8I3N279 A0A8I3N2I7 A0A8I3NBB4 A0A8I3NE83 A0A8I3P300 A0A8I3PHP8 A0A8I3PSW5 A0A8I3PVZ3 A0A8I3QRM6 A0A8I3QUB8 A0A8I3S0X8 A0A8I3S4W3 A0A8I3SCV5 B3RFJ1 B8K1W7 Q29476 Q6UR05 Q9MZY0	ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABHD14A Abcc4 Abcg2 CNDP2 CYP2E1 GGT1 GGT6 GGT7 GSTP1 LOC119874463 LOC119876946 MRP1 SULT1A1 SULT1C4 SULT1E1 UGT1A6
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A8I3NGY1 A0A8I3NXI8 A0A8I3PMT9 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PTPN11
Interleukin-1 signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ADRM1 26S proteasome ubiquitin receptor Cullin 1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase pellino homolog E3 ubiquitin-protein ligase pellino homolog IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Interleukin 1 receptor accessory protein Interleukin 1 receptor associated kinase 3 Interleukin 1 receptor type 1 Interleukin 1 receptor type 2 Interleukin-1 receptor antagonist protein Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Interleukin-1 Mitogen-activated protein kinase kinase kinase 3 Mitogen-activated protein kinase kinase kinase 7 Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Pellino E3 ubiquitin protein ligase family member 3 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RELA proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Sequestosome 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Toll interacting protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein cullin-RING-type E3 NEDD8 transferase mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A8I3MKL4 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MR89 A0A8I3N0P1 A0A8I3N165 A0A8I3N2A1 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N5F6 A0A8I3N7L6 A0A8I3N9G3 A0A8I3NBF5 A0A8I3NFB9 A0A8I3NH42 A0A8I3NHA9 A0A8I3NJ31 A0A8I3NMB6 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPR4 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NUC6 A0A8I3NVB6 A0A8I3NW81 A0A8I3NXK9 A0A8I3NXW3 A0A8I3NZN1 A0A8I3P046 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4Z1 A0A8I3P6I7 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PGC5 A0A8I3PJH9 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PLL0 A0A8I3PN81 A0A8I3PV99 A0A8I3PZT2 A0A8I3Q059 A0A8I3Q209 A0A8I3QV78 A0A8I3QYD0 A0A8I3RRR7 A0A8I3RT39 A0A8I3RUU8 A0A8I3RXV3 A0A8I3RY59 A0A8I3RZD9 A0A8I3S1Z6 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P63050 Q6F3J0 Q9BEH0	ADRM1 CHUK CUL1 IKBKB IKBKG IL1A IL1B IL1R1 IL1R2 IL1RAP IL1RN IRAK1 IRAK2 IRAK3 IRAK4 LOC100686569 LOC100687259 LOC119881719 MAP2K6 MAP3K3 MAP3K7 MYD88 NFKB1 NFKBIA PELI1 PELI2 PELI3 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMB1 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RELA RPS27A SKP1 SQSTM1 TAB1 TAB2 TAB3 TOLLIP TRAF6 UBA52 UBB UBC UBCEP2 UBE2N
FGFR2c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NTD6 A0A8I3NV07 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 7 Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Neurocan Sulfotransferase Versican core protein	A0A8I3MD46 A0A8I3MZ05 A0A8I3N108 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NAW4 A0A8I3NGD4 A0A8I3NHS7 A0A8I3NUF9 A0A8I3NUH2 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3Q1Q4 A0A8I3Q2X9 A0A8I3Q6I3 A0A8I3RX33 E2RLE9 Q29393	BCAN BGN CHPF CHPF2 CHST11 CHST12 CHST13 CHST3 CHST7 CHST9 CHSY1 CHSY3 CSGALNACT1 CSGALNACT2 CSPG4 CSPG5 DCN DCN1C NCAN VCAN

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