RHOQ GTPase cycle
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- ABCC7
- ARHGAP1
- ARHGAP17
- ARHGAP21
- ARHGAP26
- ARHGAP32
- ARHGAP33
- ARHGAP35
- ARHGAP5
- ARHGEF7
- ARL13B
- CAV
- CAV1
- CDC42
- CDC42BPA
- CDC42BPB
- CDC42EP1
- CDC42EP2
- CDC42EP3
- CFTR
- CPNE8
- CXNK1
- DEPDC1B
- DIAPH3
- DLC1
- FNBP1
- GFOD1
- GIT1
- GIT2
- GJA1
- GOPC
- GRLF1
- IQGAP3
- JUP
- LAMTOR1
- LOC119867035
- MPP7
- OPHN1
- P190A
- PAK1
- PAK2
- PAK4
- PLEKHG3
- PREX1
- RAB7
- RAB7A
- RHOQ
- SCRIB
- SLC1A5
- SLC4A7
- SNAP23
- SRGAP2
- STEAP3
- STOM
- SYDE1
- TFRC
- TRIP10
- VAMP3
- VANGL1
- WASL
- WWP2
- p190ARHOGAP
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PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
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- AILIM
- AREG
- BDNF
- BTC
- CD19
- CD28
- CD80
- CD86
- EGF
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- ESR1
- ESR2
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FYN
- GAB1
- GAB2
- GRB2
- HBEGF
- HGF
- ICOS
- IER3
- IL1RAP
- IL33
- INS
- INSR
- IRAK1
- IRAK4
- IRS1
- IRS2
- KGF
- KIT
- KITLG
- KL
- KLB
- LCK
- LOC100856339
- MAPK1
- MAPK3
- MET
- MGF
- MYD88
- NRG1
- NRG2
- NRG3
- NTF3
- NTF4
- NTRK2
- NTRK3
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PIK3AP1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP5K1A
- PIP5K1B
- PIP5K1C
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PTPN11
- RAC1
- RAC2
- RHOG
- SRC
- STRN
- TGFA
- TRAF6
- TRAT1
- VAV1
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PI3K/AKT Signaling
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- AILIM
- AREG
- BDNF
- BTC
- CD19
- CD28
- CD80
- CD86
- EGF
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- ESR1
- ESR2
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FYN
- GAB1
- GAB2
- GRB2
- HBEGF
- HGF
- ICOS
- IL1RAP
- IL33
- IRAK1
- IRAK4
- IRS1
- IRS2
- KGF
- KIT
- KITLG
- KL
- KLB
- LCK
- LOC100856339
- MAPKAP1
- MET
- MGF
- MLST8
- MTOR
- MYD88
- NRG1
- NRG2
- NRG3
- NTF3
- NTF4
- NTRK2
- NTRK3
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PDPK1
- PIK3AP1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PRR5
- PTPN11
- RAC1
- RAC2
- RHOG
- RICTOR
- SGK1
- SRC
- STRN
- TGFA
- TRAF6
- TRAT1
- VAV1
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RAF/MAP kinase cascade
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- ACTN2
- ANGPT1
- AREG
- BTC
- CALM2
- CAMK2A
- CAMK2B
- CAMK2G
- CSF2
- CSF2RA
- CSF2RB
- DLG2
- DLG3
- DLG4
- EGF
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FRS3
- FYN
- GDNF
- GFRA1
- GFRA2
- GFRA4
- GRB2
- GRIN1
- GRIN2B
- GRIN2D
- HBEGF
- HGF
- HRAS
- IL2
- IL2RA
- IL2RB
- IL3
- IL5
- IL5RA
- IRS1
- IRS2
- JAK1
- JAK2
- JAK3
- KGF
- KIT
- KITLG
- KL
- KLB
- KRAS
- LAT
- LRRC7
- MAPK1
- MAPK3
- MET
- MGF
- NCAM1
- NEFL
- NMDAR1
- NRAPGEP
- NRAS
- NRG1
- NRG2
- NRG3
- NRTN
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PDZGEF1
- PEA15
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PSPN
- PTK2
- PTPRA
- RALGDS
- RANBP9
- RAPGEF2
- RASGEF1A
- RASGRF1
- RASGRF2
- RASGRP1
- RASGRP3
- RASGRP4
- RET
- RGL1
- RGL2
- RGL3
- SHC1
- SHC2
- SHC3
- SOS1
- SPTA1
- SPTAN1
- SPTB
- SPTBN1
- SPTBN2
- SPTBN5
- TEK
- TGFA
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PI3K Cascade
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- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- GAB1
- GAB2
- GRB2
- IRS1
- IRS2
- KGF
- KL
- KLB
- PIK3C3
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PIK3R4
- PTPN11
- TLR9
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PI-3K cascade:FGFR2
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- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR2
- FRS2
- GAB1
- GRB2
- KGF
- PIK3CA
- PIK3R1
- PTPN11
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PI-3K cascade:FGFR3
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- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGF9
- FGFR3
- FRS2
- GAB1
- GRB2
- PIK3CA
- PIK3R1
- PTPN11
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PI-3K cascade:FGFR1
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- FGF1
- FGF10
- FGF17
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FRS2
- GAB1
- GRB2
- KL
- PIK3CA
- PIK3R1
- PTPN11
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Negative regulation of FGFR2 signaling
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- CBL
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR2
- FRS2
- GRB2
- KGF
- MAPK1
- MAPK3
- PTPN11
- RPS27A
- UBA52
- UBB
- UBC
- UBCEP2
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Negative regulation of FGFR3 signaling
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- CBL
- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGF9
- FGFR3
- FRS2
- GRB2
- MAPK1
- MAPK3
- PTPN11
- RPS27A
- UBA52
- UBB
- UBC
- UBCEP2
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Negative regulation of FGFR1 signaling
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- ANOS1
- CBL
- FGF1
- FGF10
- FGF17
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FRS2
- GRB2
- KL
- MAPK1
- MAPK3
- PTPN11
- RPS27A
- UBA52
- UBB
- UBC
- UBCEP2
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FGFRL1 modulation of FGFR1 signaling
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- FGF10
- FGF17
- FGF18
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGFRL1
- SPRED1
- SPRED2
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FRS-mediated FGFR2 signaling
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- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR2
- FRS2
- FRS3
- GRB2
- HRAS
- KGF
- KRAS
- NRAS
- PTPN11
- SOS1
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SHC-mediated cascade:FGFR2
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- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR2
- GRB2
- HRAS
- KGF
- KRAS
- NRAS
- SHC1
- SOS1
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Phospholipase C-mediated cascade; FGFR2
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- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR2
- KGF
- PLCG1
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FRS-mediated FGFR3 signaling
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- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGF9
- FGFR3
- FRS2
- FRS3
- GRB2
- HRAS
- KRAS
- NRAS
- PTPN11
- SOS1
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SHC-mediated cascade:FGFR3
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- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGF9
- FGFR3
- GRB2
- HRAS
- KRAS
- NRAS
- SHC1
- SOS1
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FGFR3c ligand binding and activation
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- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGF9
- FGFR3
- GALNT3
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Phospholipase C-mediated cascade; FGFR3
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- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF7A
- FGF8
- FGF8B
- FGF9
- FGFR3
- PLCG1
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FGFR2c ligand binding and activation
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- FGF1
- FGF16
- FGF17
- FGF18
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR2
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FRS-mediated FGFR1 signaling
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- FGF1
- FGF10
- FGF17
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FRS2
- FRS3
- GRB2
- HRAS
- KL
- KRAS
- NRAS
- PTPN11
- SOS1
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SHC-mediated cascade:FGFR1
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- FGF1
- FGF10
- FGF17
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- GRB2
- HRAS
- KL
- KRAS
- NRAS
- SHC1
- SOS1
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Downstream signaling of activated FGFR1
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- FGF1
- FGF10
- FGF17
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FLRT1
- FLRT2
- FLRT3
- KL
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Phospholipase C-mediated cascade: FGFR1
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- FGF1
- FGF10
- FGF17
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- KL
- PLCG1
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FGFR1c ligand binding and activation
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- ANOS1
- FGF1
- FGF17
- FGF20
- FGF23
- FGF3A
- FGF4
- FGF4B
- FGF5
- FGF6
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- GIPC1
- TGFBR3
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