FGFR2c ligand binding and activation
|
|
|
- AFGF
- FGF1
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF6
- FGF6A
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR2
- Fgf4
- HBGF-1
|
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FGFR2b ligand binding and activation
|
|
|
- AFGF
- FGF1
- FGF10
- FGF2
- FGF3
- FGF5B
- FGF5C
- FGF7
- FGFA
- FGFBP
- FGFBP1
- FGFR2
- HBGF-1
|
|
Phospholipase C-mediated cascade; FGFR2
|
|
|
- AFGF
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR2
- Fgf4
- HBGF-1
- PLCG1
|
|
PI-3K cascade:FGFR2
|
|
|
- AFGF
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR2
- FRS2
- Fgf4
- GAB1
- GRB2
- HBGF-1
- PIK3CA
- PIK3R1
- PTPN11
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SHC-mediated cascade:FGFR2
|
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|
- AFGF
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR2
- Fgf4
- GRB2
- HBGF-1
- KRAS
- NRAS
- SHC1
- SOS1
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FRS-mediated FGFR2 signaling
|
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|
- AFGF
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR2
- FRS2
- FRS3
- Fgf4
- GRB2
- HBGF-1
- KRAS
- NRAS
- PTPN11
- SOS1
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PI3K/AKT Signaling
|
|
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- AFGF
- AREG
- BTC
- CD19
- CD28
- CD80
- CD86
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- ESR
- ESR1
- ESR2
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF8A
- FGF9
- FGFA
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FYN
- Fgf4
- GAB1
- GAB2
- GRB2
- HBEGF
- HBGF-1
- HGF
- ICOS
- IL1RL1
- IL33
- IRAK1
- IRAK4
- IRS1
- IRS2
- KIT
- KITLG
- KL
- KLB
- LCK
- MET
- MYD88
- NR3A1
- NR3A2
- NRG1
- NRG2
- NRG3
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PDPK1
- PIK3AP1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PTPN11
- RAC2
- RHOG
- SCF
- SRC
- STRN
- TGFA
- TRAF6
- TRAT1
- VAV1
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|
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
|
|
|
- AFGF
- AREG
- BTC
- CD19
- CD28
- CD80
- CD86
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- ERK2
- ESR
- ESR1
- ESR2
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF8A
- FGF9
- FGFA
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FYN
- Fgf4
- GAB1
- GAB2
- GRB2
- HBEGF
- HBGF-1
- HGF
- ICOS
- IER3
- IL1RL1
- IL33
- INS
- INSR
- IRAK1
- IRAK4
- IRS1
- IRS2
- KIT
- KITLG
- KL
- KLB
- LCK
- MAPK1
- MAPK3
- MET
- MYD88
- NR3A1
- NR3A2
- NRG1
- NRG2
- NRG3
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PIK3AP1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP5K1A
- PIP5K1B
- PIP5K1C
- PIP5K2C
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5D
- PPP2R5E
- PRKM1
- PTPN11
- RAC2
- RHOG
- SCF
- SRC
- STRN
- TGFA
- TRAF6
- TRAT1
- VAV1
|
|
Nuclear events mediated by NFE2L2
|
|
|
- CREBBP
- EP300
- NFE2L2
- PRKAA2
|
|
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
|
|
|
- CUL1
- GSK3B
- NFE2L2
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSMF1
- RPS27A
- SKP1
- SKP1A
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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KEAP1-NFE2L2 pathway
|
|
|
- CUL3
- KEAP1
- MAP1ALC3
- MAP1LC3
- MAP1LC3B
- MUL1
- NFE2L2
- NPLOC4
- PRKCI
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- RPS27A
- SESN1
- SESN2
- SQSTM1
- SUG1
- TRAP2
- TRIM21
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBXN7
- UFD1
- VCP
|
|
Sensory perception of sweet, bitter, and umami (glutamate) taste
|
|
|
- GNAT3
- GNB1
- GNB3
- GNG13
- ITPR3
- LOC782957
- T2R10C
- TAS1R1
- TAS1R2
- TAS1R3
- TAS2R1
- TAS2R16
- TAS2R3
- TAS2R39
- TAS2R4
- TAS2R40
- TAS2R46
- TAS2R7
- TAS2R8
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|
Estrogen-dependent gene expression
|
- Cbp/p300-interacting transactivator 1
- Core-binding factor subunit beta
- Cyclin-T1
- Cyclin-dependent kinase 9
- DNA-directed RNA polymerase II subunit E
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase subunit
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Estrogen receptor
- Forkhead box A1
- GATA binding protein 3
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- Growth regulating estrogen receptor binding 1
- Heat shock protein HSP 90-alpha
- Heat shock protein HSP 90-beta
- Histone H2A.J
- Histone H2A.V
- Histone H2A/H2B/H3 domain-containing protein
- Histone H2A/H2B/H3 domain-containing protein
- Histone H2A/H2B/H3 domain-containing protein
- Histone H2A
- Histone H2A
- Histone H2A
- Histone H2A
- Histone H2B type 1
- Histone H2B
- Histone H2B
- Histone H2B
- Histone H2B
- Histone H2B
- Histone H2B
- Histone H2B
- Histone H3.1
- Histone H3.2
- Histone H3.3
- Histone H4
- Histone acetyltransferase
- Histone acetyltransferase
- Histone deacetylase 1
- Lysine-specific histone demethylase
- Mediator of RNA polymerase II transcription subunit 1
- Nuclear receptor coactivator
- Nuclear receptor coactivator
- Nuclear receptor coactivator
- Nuclear receptor interacting protein 1
- Nuclear receptor subfamily 5 group A member 2
- Progesterone receptor
- Prostaglandin E synthase 3
- Ral transcription factor IIA subunit 1
- Receptor protein-tyrosine kinase
- Runt-related transcription factor
- Sp1 transcription factor
- TATA-box-binding protein
- TLE family member 3, transcriptional corepressor
- Transcription initiation factor IIA subunit 2
- Upstream stimulatory factor 1
- Upstream transcription factor 2, c-fos interacting
- YY1 protein
- Zinc finger protein 217
- [histone H3]-trimethyl-L-lysine(9) demethylase
- histone acetyltransferase
- histone acetyltransferase
- peptidylprolyl isomerase
- type I protein arginine methyltransferase
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|
- CBFB
- CCNT1
- CDK9
- CITED1
- CREBBP
- EP300
- ERBB4
- ESR
- ESR1
- FKBP4
- FOXA1
- GATA3
- GREB1
- GTF2A1
- GTF2A2
- GTF2F1
- GTF2F2
- H2AC12
- H2AC18
- H2AC21
- H2AC6
- H2AJ
- H2AV
- H2AZ2
- H2B
- H2BC26
- H2BC5
- H3-3A
- H3-3B
- H3F3A
- H3F3B
- HDAC1
- HIST1H2BI
- HSP90A
- HSP90AA1
- HSP90AB1
- HSPC3
- HSPCA
- HSPCB
- KAT2B
- KAT5
- KDM1A
- KDM4B
- LOC528006
- MED1
- MSG1
- NCOA1
- NCOA2
- NCOA3
- NR3A1
- NR5A2
- NRIP1
- PGR
- POLR2A
- POLR2B
- POLR2C
- POLR2D
- POLR2E
- POLR2F
- POLR2G
- POLR2H
- POLR2I
- POLR2J
- POLR2K
- POLR2L
- PRMT1
- PTGES3
- RUNX1
- SP1
- TBP
- TLE3
- USF1
- USF2
- YY1
- ZNF217
|
|
Class B/2 (Secretin family receptors)
|
|
|
- ADGRE3
- ADGRE5
- CD55
- CRH
- CRHBP
- CRHR2
- LOC112447333
- LOC508459
- PTH
- PTH1R
- PTH2
- PTH2R
- PTHLH
- SPC
- UCN2
- UCN3
|
|
Toll Like Receptor 9 (TLR9) Cascade
|
|
|
|
|
Macroautophagy
|
|
|
- AMBRA1
- APG4B
- ATG10
- ATG101
- ATG12
- ATG13
- ATG14
- ATG16L1
- ATG3
- ATG4A
- ATG4B
- ATG4C
- ATG4D
- ATG5
- ATG7
- ATG9
- ATG9A
- ATG9B
- AUT2B
- BECN1
- CHMP2A
- CHMP2B
- CHMP3
- CHMP4A
- CHMP4B
- CHMP4C
- CHMP6
- CHMP7
- DNCL1
- DYNLL1
- DYNLL2
- GABARAP
- GABARAPL1
- GABARAPL2
- GBL
- GEF2
- LAMTOR1
- LAMTOR2
- LAMTOR3
- LAMTOR4
- LAMTOR5
- LST8
- MAP1ALC3
- MAP1LC3
- MAP1LC3A
- MAP1LC3B
- MAP1LC3C
- MGC138057
- MLST8
- MTMR14
- MTOR
- PIK3C3
- PIK3R4
- PRKAA1
- PRKAA2
- PRKAB1
- PRKAB2
- PRKAG1
- PRKAG2
- PRKAG3
- RB1CC1
- RHEB
- RPTOR
- RRAGA
- RRAGB
- RRAGC
- RRAGD
- SLC38A9
- TSC1
- ULK1
- UVRAG
- VPS24
- WDR45
- WDR45B
- WIPI1
- WIPI2
|
|
RHO GTPases Activate NADPH Oxidases
|
|
|
- CYBA
- CYBB
- ERK2
- MAPK1
- MAPK11
- MAPK14
- MAPK3
- NCF1
- NCF2
- NCF4
- NOX1
- NOX3
- NOXO1
- PIK3C3
- PIK3R4
- PIN1
- PRKCB
- PRKCB1
- PRKCD
- PRKCZ
- PRKM1
- RAC2
- S100A8
- S100A9
|
|
PI3K Cascade
|
|
|
- AFGF
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF8A
- FGF9
- FGFA
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- Fgf4
- GAB1
- GAB2
- GRB2
- HBGF-1
- IRS1
- IRS2
- KL
- KLB
- PIK3C3
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PIK3R4
- PTPN11
- TLR9
|
|
ABC-family proteins mediated transport
|
|
|
- ABCA4
- ABCB1
- ABCB4
- ABCB9
- ABCC1
- ABCC10
- ABCC11
- ABCC2
- ABCC3
- ABCC5
- ABCC9
- ABCF1
- ABCR
- CFTR
- DERL1
- DERL2
- DERL3
- EIF2A
- EIF2S1
- EIF2S2
- EIF2S3
- ERLEC1
- ERLIN1
- ERLIN2
- KCNJ11
- LOC515333
- MRP1
- OS9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- RNF185
- RNF5
- RPS27A
- SEL1L
- SPFH2
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VCP
|
|
Synthesis of PA
|
|
|
- ACP6
- AGPAT1
- AGPAT2
- AGPAT3
- AGPAT4
- AGPAT5
- AGPAT6
- CPLA2
- DDHD1
- DDHD2
- FAM73B
- GNPAT
- GPAM
- GPAT2
- GPAT3
- GPAT4
- GPD1
- GPD1L
- GPD2
- LIPH
- LOC516378
- LOC613966
- LPCAT1
- LPCAT4
- MIGA1
- MIGA2
- PLA2G12A
- PLA2G1B
- PLA2G2A
- PLA2G2D1
- PLA2G2E
- PLA2G4
- PLA2G4A
- PLA2G4D
- PLA2R1
- PLD1
- PLD2
- PLD6
|
|
Lysosphingolipid and LPA receptors
|
|
|
- EDG1
- GPR92
- LPAR1
- LPAR2
- LPAR3
- LPAR5
- PLPPR1
- PLPPR2
- PLPPR3
- PLPPR4
- PLPPR5
- S1PR1
- S1PR2
- S1PR3
- S1PR5
|
|
Synaptic adhesion-like molecules
|
|
|
- DLG1
- DLG3
- DLG4
- FLOT1
- FLOT2
- GRIA1
- GRIA3
- LRFN1
- LRFN2
- LRFN3
- LRFN4
- PTPRD
- PTPRF
- PTPRS
- SALM4
|
|
Phase 4 - resting membrane potential
|
|
|
- IRK1
- KCNJ12
- KCNJ14
- KCNJ2
- KCNJ4
- KCNK1
- KCNK10
- KCNK12
- KCNK13
- KCNK15
- KCNK16
- KCNK17
- KCNK18
- KCNK2
- KCNK3
- KCNK4
- KCNK5
- KCNK7
- KCNK9
|
|
Adrenaline signalling through Alpha-2 adrenergic receptor
|
|
|
|
|
Adrenaline,noradrenaline inhibits insulin secretion
|
|
|
- ADCY5
- ADCY6
- ADRA2A
- ADRA2C
- GNAI1
- GNAI2
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNGT1
- GNGT12
- GNGT2
- GNGT3
- GNGT5
- GNGT7
- GNGT8
|
|