MyD88 cascade initiated on plasma membrane
|
|
|
|
|
Generic Transcription Pathway
|
|
|
- BORIS
- CCNC
- CDK8
- CRSP6
- CRSP8
- ELOVL1
- GLI4
- KRBA1
- LOC100124429
- LOC100125304
- LOC100139104
- LOC100139345
- LOC100299712
- LOC100336208
- LOC100336448
- LOC100336984
- LOC100847180
- LOC100847773
- LOC100848895
- LOC104968476
- LOC104970105
- LOC107131241
- LOC506495
- LOC508131
- LOC509810
- LOC516156
- LOC616720
- MED1
- MED10
- MED12
- MED13
- MED14
- MED15
- MED16
- MED17
- MED20
- MED23
- MED24
- MED25
- MED26
- MED27
- MED30
- MED31
- MED4
- MED6
- MED7
- RHIT
- SOH1
- THRAP6
- TRAP25
- TRIM28
- ZFP1
- ZFP14
- ZFP2
- ZFP28
- ZFP37
- ZFP69
- ZFP82
- ZFP90
- ZIM3
- ZKSCAN1
- ZKSCAN4
- ZKSCAN5
- ZKSCAN7
- ZKSCAN8
- ZNF10
- ZNF112
- ZNF114
- ZNF135
- ZNF140
- ZNF157
- ZNF169
- ZNF175
- ZNF18
- ZNF180
- ZNF181
- ZNF189
- ZNF19
- ZNF192
- ZNF200
- ZNF202
- ZNF205
- ZNF212
- ZNF214
- ZNF226
- ZNF227
- ZNF23
- ZNF235
- ZNF24
- ZNF248
- ZNF25
- ZNF250
- ZNF26
- ZNF263
- ZNF268
- ZNF274
- ZNF275
- ZNF286A
- ZNF300
- ZNF304
- ZNF311
- ZNF331
- ZNF33B
- ZNF345
- ZNF350
- ZNF354A
- ZNF354B
- ZNF354C
- ZNF382
- ZNF383
- ZNF41
- ZNF416
- ZNF432
- ZNF436
- ZNF445
- ZNF45
- ZNF454
- ZNF484
- ZNF496
- ZNF500
- ZNF514
- ZNF529
- ZNF548
- ZNF550
- ZNF554
- ZNF555
- ZNF558
- ZNF565
- ZNF566
- ZNF568
- ZNF569
- ZNF570
- ZNF584
- ZNF596
- ZNF599
- ZNF605
- ZNF613
- ZNF614
- ZNF619
- ZNF621
- ZNF624
- ZNF641
- ZNF642
- ZNF667
- ZNF668
- ZNF684
- ZNF688
- ZNF689
- ZNF70
- ZNF703
- ZNF704
- ZNF706
- ZNF710
- ZNF713
- ZNF74
- ZNF746
- ZNF750
- ZNF75A
- ZNF77
- ZNF770
- ZNF772
- ZNF774
- ZNF782
- ZNF786
- ZNF791
- ZNF792
- ZNF793
- ZNF804B
- ZNF805
- ZNF839
- ZNF892
- ZSCAN25
- znf496
|
|
Negative regulation of FGFR3 signaling
|
|
|
- AFGF
- CBL
- ERK2
- FGF1
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF6A
- FGF8
- FGF9
- FGFA
- FGFR3
- FRS2
- Fgf4
- GRB2
- HBGF-1
- MAPK1
- MAPK3
- PRKM1
- PTPN11
- RPS27A
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
Reversible hydration of carbon dioxide
|
|
|
- CA1
- CA12
- CA13
- CA14
- CA2
- CA3
- CA4
- CA5A
- CA5B
- CA6
- CA9
|
|
The NLRP3 inflammasome
|
|
|
- HSP90AB1
- HSPC3
- HSPCB
- NLRP3
- P2RX7
- PANX
- PANX1
- PSTPIP1
- PYCARD
- SUGT1
- TXN
- TXNIP
|
|
Negative regulation of FGFR1 signaling
|
|
|
- AFGF
- CBL
- ERK2
- FGF1
- FGF10
- FGF17
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF5
- FGF5C
- FGF6
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR1
- FRS2
- Fgf4
- GRB2
- HBGF-1
- KL
- MAPK1
- MAPK3
- PRKM1
- PTPN11
- RPS27A
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
IFNG signaling activates MAPKs
|
|
|
- ERK2
- IFNG
- IFNGR1
- IFNGR2
- JAK1
- JAK2
- MAPK1
- MAPK3
- PRKM1
|
|
Activation of Matrix Metalloproteinases
|
|
|
- COL18A1
- CTRB1
- CTSK
- CTSL
- CTSL1
- ELANE
- FURIN
- KLK1
- KLKB1
- KLNA1
- LOC100139881
- LOC112441463
- LOC112442231
- LOC509956
- LOC540321
- MMP11
- MMP13
- MMP14
- MMP15
- MMP16
- MMP17
- MMP2
- MMP24
- MMP25
- MMP3
- MMP7
- MMP8
- MMP9
- PLG
- PRSS2
- TIMP2
- TPSB1
|
|
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
|
|
|
|
|
Interleukin-1 signaling
|
|
|
- ADRM1
- CHUK
- CUL1
- IKBKB
- IKBKG
- IKKA
- IL1A
- IL1B
- IL1R1
- IL1R2
- IL1RN
- IRAK1
- IRAK2
- IRAK3
- IRAK4
- MAP2K6
- MAP3K3
- MAP3K7
- MYD88
- NEMO
- NFKB1
- NFKBIA
- PELI1
- PELI2
- PELI3
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RELA
- RPS27A
- SKP1
- SKP1A
- SQSTM1
- SUG1
- TAB1
- TAB2
- TAB3
- TOLLIP
- TRAF6
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBE2N
- bIkBa
|
|
TWIK-related alkaline pH activated K+ channel (TALK)
|
|
|
|
|
Cytosolic sulfonation of small molecules
|
|
|
- ABHD14B
- BPNT1
- BPNT2
- LOC100300896
- PODXL2
- STP
- SULT1A1
- SULT1B1
- SULT1C2
- SULT1E1
- SULT2A1
- SULT2B1
- SULT4A1
- SULT6B1
- TPST1
- TPST2
|
|
WNT mediated activation of DVL
|
|
|
- CK2A1
- CK2N
- CSNK1E
- CSNK2A1
- CSNK2A2
- CSNK2B
- DVL1
- DVL2
- DVL3
- PIP5K1B
|
|
Erythropoietin activates RAS
|
|
|
- CRKL
- EPO
- EPOR
- GRB2
- IRS2
- JAK2
- LYN
- RAPGEF1
- SHC1
- VAV1
|
|
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
|
|
|
- ADRM1
- AIK
- AIRK1
- ANAPC1
- ANAPC10
- ANAPC11
- ANAPC15
- ANAPC16
- ANAPC2
- ANAPC4
- ANAPC5
- ANAPC7
- ANAPC8
- ARK1
- AURA
- AURKA
- AURKB
- AYK1
- BTAK
- CDC16
- CDC20
- CDC23
- CDC26
- CDC27
- FZR1
- IAK1
- PLK1
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RB1
- RPS27A
- SKP2
- STK15
- STK6
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBCH10
- UBE2C
- UBE2D1
- UBE2E1
- UBE2S
|
|
Regulation of Complement cascade
|
|
|
- ADIB
- BF
- C1QA
- C1QB
- C1R
- C1S
- C2
- C3
- C3AR1
- C4A
- C5
- C5AR1
- C5AR2
- C5L2
- C7
- C8A
- C8B
- C9
- CD19
- CD55
- CD59
- CD81
- CFB
- CFH
- CFHR5
- CFI
- CLU
- CPB2
- CPN1
- CPN2
- ELANE
- F2
- GPR77
- LOC100336868
- LOC107131209
- LOC519737
- LOC616002
- SERPING1
- VTN
|
|
Integrin cell surface interactions
|
|
|
- BSG
- CD18
- CD44
- CD47
- CDH1
- COL13A1
- COL16A1
- COL18A1
- COL4A1
- COL4A3
- COMP
- F11R
- FBN1
- FN1
- IBSP
- ICAM1
- ICAM3
- ICAM5
- ITGA1
- ITGA10
- ITGA11
- ITGA2
- ITGA2B
- ITGA3
- ITGA4
- ITGA6
- ITGA9
- ITGAL
- ITGAM
- ITGAV
- ITGAX
- ITGB1
- ITGB2
- ITGB3
- ITGB5
- ITGB6
- ITGB7
- ITGB8
- JAM1
- JAM2
- LDC
- LOC534578
- LOC616254
- LUM
- P2RX5
- PECAM1
- SPP1
- THBS1
- TNC
- VCAM1
- VTN
|
|
Signaling by Insulin receptor
|
|
|
|
|
Ion channel transport
|
|
|
- ATP6A1
- ATP6AP1
- ATP6B1
- ATP6B2
- ATP6C
- ATP6D
- ATP6E
- ATP6G
- ATP6G1
- ATP6H
- ATP6IP1
- ATP6N1B
- ATP6S1
- ATP6S14
- ATP6V0A1
- ATP6V0A2
- ATP6V0A4
- ATP6V0B
- ATP6V0C
- ATP6V0D1
- ATP6V0D2
- ATP6V0E
- ATP6V0E1
- ATP6V0E2
- ATP6V1A
- ATP6V1A1
- ATP6V1B1
- ATP6V1B2
- ATP6V1C1
- ATP6V1C2
- ATP6V1E1
- ATP6V1E2
- ATP6V1F
- ATP6V1G1
- ATP6V1G2
- ATP6V1G3
- ATP6V1H
- LOC101904667
- SVOPL
- TCIRG1
- VATC
- VATF
- VPATPD
|
|
Collagen chain trimerization
|
|
|
- COL10A1
- COL11A1
- COL11A2
- COL12A1
- COL13A1
- COL14A1
- COL16A1
- COL17A1
- COL18A1
- COL1A1
- COL1A2
- COL20A1
- COL23A1
- COL26A1
- COL27A1
- COL28A1
- COL2A1
- COL3A1
- COL5A1
- COL5A3
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL8A1
- COL8A2
|
|
Phosphorylation of CD3 and TCR zeta chains
|
|
|
- BLA-DQB
- BOLA-DQA1
- BOLA-DQA2
- BOLA-DQA5
- BOLA-DRA
- BOLA-DRB2
- BOLA-DRB3
- BOLA-DYA
- BoLA-DIB
- BoLA-DRA
- BoLA-DYB
- CD247
- CD3D
- CD3E
- CD3G
- CD4
- CSK
- DYB
- HLA-DRA
- LCK
- LOC100848815
- PAG1
- PTPN22
- PTPRC
- PTPRJ
- TRAV29-1
|
|
Citric acid cycle (TCA cycle)
|
- Aconitate hydratase, mitochondrial
- Citrate synthase, mitochondrial
- Fumarate hydratase, mitochondrial
- Heat shock protein 75 kDa, mitochondrial
- Isocitrate dehydrogenase [NADP], mitochondrial
- Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
- Isocitrate dehydrogenase [NAD] subunit, mitochondrial
- Isocitrate dehydrogenase [NAD] subunit, mitochondrial
- Malate dehydrogenase, mitochondrial
- NAD(P) transhydrogenase, mitochondrial
- Succinate dehydrogenase [ubiquinone] cytochrome b small subunit
- Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
- Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
- Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
|
|
- ACO2
- CS
- CYB560
- FH
- HSP75
- HSPC5
- IDH2
- IDH3A
- IDH3B
- IDH3G
- MDH2
- NNT
- SDHA
- SDHB
- SDHC
- SDHD
- SUCLA2
- SUCLG1
- SUCLG2
- TRAP1
|
|
Metabolism of steroid hormones
|
|
|
|
|
Signal regulatory protein family interactions
|
|
|
- CD47
- FYB
- GRB2
- PTK2B
- SCAP2
- SIRPA
- SIRPB1
- SKAP2
|
|
Negative regulation of the PI3K/AKT network
|
|
|
|
|