GlyCosmos Portal

Bos taurus (cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (1341) Glycans (1011) Glycoproteins (1221) Lectins (76) Pathways (557)

Displaying entries **526 - 550** of **557** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol
Mitochondrial protein degradation	2-oxoglutarate dehydrogenase complex component E1 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial 60 kDa heat shock protein, mitochondrial ACOT2 protein ADP/ATP translocase 2 ADP/ATP translocase 3 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha ATP synthase subunit beta ATP synthase subunit d, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit ATP synthase-coupling factor 6, mitochondrial ATP-dependent Clp protease proteolytic subunit, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial Amyloid-beta A4 protein Arginase-2, mitochondrial C26H10ORF2 protein Citrate synthase, mitochondrial Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 8 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 5A, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial D-lactate dehydrogenase (cytochrome) Delta-1-pyrroline-5-carboxylate synthase Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA delta isomerase 1 Enoyl-CoA hydratase 1 Essential MCU regulator, mitochondrial Ferrochelatase, mitochondrial Fumarate hydratase, mitochondrial Glutamate dehydrogenase 1, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Isocitrate dehydrogenase [NAD] subunit, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL32m Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Lon protease homolog, mitochondrial Malate dehydrogenase, mitochondrial Malic enzyme Mitochondrial inner membrane m-AAA protease component AFG3L2 Mitochondrial-processing peptidase subunit alpha NAD kinase 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Protein-serine/threonine kinase Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial SPG7 protein Serine hydroxymethyltransferase, mitochondrial Serine protease HTRA2, mitochondrial Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Single-stranded DNA-binding protein Small ribosomal subunit protein uS10m Small ribosomal subunit protein uS2m Steroidogenic acute regulatory protein, mitochondrial Stress-70 protein, mitochondrial Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial Succinyl-CoA Transcription factor A, mitochondrial cAMP-dependent protein kinase catalytic subunit alpha isoleucine--tRNA ligase	A0A0N4STN0 A0A140T842 A0A140T871 A0A3Q1LIX4 A0A3Q1LR42 A0A3Q1LS03 A0A3Q1LS67 A0A3Q1LUG2 A0A3Q1LYU1 A0A3Q1M7B1 A0A3Q1MG52 A0A3Q1MWG7 A0A3Q1N0E1 A0A452DI36 A0A452DII8 A0A452DIR0 A0A452DJA3 A0A452DJH4 A0JNK3 A5D7A7 A6QQA9 A7E2Z6 E1BA21 F1MLB8 F1MS25 F1MTT7 F1MUZ9 F1MXW5 F1N1S0 F1N206 G3MWG4 G3MWN1 G5E5P4 O02691 P00426 P00517 P00847 P02721 P05631 P11181 P11966 P13620 P13621 P15690 P20000 P20004 P22600 P23004 P32007 P82670 P82923 Q02337 Q02370 Q04467 Q0NXR6 Q0P5M8 Q148D3 Q148J8 Q148K4 Q148N0 Q28918 Q29RK1 Q29RZ0 Q2KHU4 Q2KIE6 Q2KJH7 Q2KJI7 Q2M2S2 Q2TBI6 Q32LG3 Q3MHX5 Q3SZ20 Q3ZCH0 Q5EAD4 Q6QTG9 Q7YR75 Q8SQH5 Q95KV7	AAC3 ACAD8 ACADSB ACAT1 ACO2 ACOT2 AFG3L2 ALAS1 ALDH18A1 ALDH1B1 ALDH2 ANT2 ANT3 APP ARG2 ATP5C ATP5C1 ATP5F1A ATP5F1B ATP5F1C ATP5H ATP5J ATP5MG ATP5O ATP5PD ATP5PF ATP5PO ATP6 ATPASE6 BDH BDH1 C26H10ORF2 CLPP COX1 COX5A CS DBT DLD ECH1 ECI1 EMRE FECH FH GLUD1 GRIM19 HADH2 HMGCS2 HSD17B10 HSPA9 HSPD1 HTRA2 IARS2 IDH2 IDH3A LDHD LONP1 MDH2 ME2 MRPL12 MRPL32 MRPS10 MRPS2 MT-ATP6 MTATP6 NADK2 NDUFA13 NDUFA2 NDUFS1 NDUFS3 NDUFV1 OGDH OXCT1 OXSM PCCB PDHA1 PDHB PDK1 PMPCA PRKACA SHMT2 SLC25A5 SLC25A6 SMDT1 SPG7 SSBP1 STAR SUCLG2 TFAM TWNK UQCRC2 UQCRQ
Ubiquinol biosynthesis	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 4-hydroxybenzoate polyprenyltransferase, mitochondrial 5-demethoxyubiquinone hydroxylase, mitochondrial Atypical kinase COQ8A, mitochondrial Decaprenyl diphosphate synthase subunit 1 Decaprenyl diphosphate synthase subunit 2 Ubiquinone biosynthesis O-methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial Ubiquinone biosynthesis protein COQ9, mitochondrial	A6QR05 E1BK08 F1N1G6 F1N5A4 F6RJN8 Q0P5A2 Q29RI0 Q2KIL4 Q2NL34 Q58CW1	ADCK3 CABC1 COQ2 COQ3 COQ4 COQ5 COQ6 COQ7 COQ8A COQ9 PDSS1 PDSS2
Triglyceride biosynthesis	2-acylglycerol O-acyltransferase 1 Acyltransferase Alkylglycerol monooxygenase Glycerol kinase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial O-acyltransferase glycerol kinase glycerol kinase phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A3Q1LKP8 A0A3Q1LV95 E1B9D5 E1BLQ9 F1MDT6 F1MIW3 F1MLW9 F1MSV5 G3MYF6 Q0IID9 Q2NKZ8 Q70VZ7	AGMO DGAT1 GK GK2 GPAM GPAT2 LOC538702 LPIN1 LPIN2 LPIN3 MOGAT1 MOGAT3
Synthesis of very long-chain fatty acyl-CoAs	17beta-estradiol 17-dehydrogenase Elongation of very long chain fatty acids protein 2 Elongation of very long chain fatty acids protein 3 Elongation of very long chain fatty acids protein 6 Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Malonate--CoA ligase ACSF3, mitochondrial Trans-2,3-enoyl-CoA reductase-like Very long chain fatty acid elongase 5 Very long chain fatty acid elongase 7 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain 3-oxoacyl-CoA reductase Very-long-chain enoyl-CoA reductase long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase	A0A3Q1LPX2 A0A3Q1LWT4 A0JNC4 A4FUF2 A6H7H3 A6QNQ7 A7YY55 E1BBR7 F1MBW3 F1MEX9 F1MXJ1 F1MXT1 F1N0H2 F6RUH3 Q1LZF6 Q2KJD9 Q3SZ89 Q3ZCD7 Q58DN7	ACSF3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ELOVL2 ELOVL3 ELOVL5 ELOVL6 ELOVL7 GPSN2 HACD1 HACD2 HACD3 HACD4 HSD17B12 HSD17B3 LOC789567 MGC139109 PTPLAD1 SRD5A2L2 TECR TECRL
Androgen biosynthesis	17beta-estradiol 17-dehydrogenase 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3-oxo-5-alpha-steroid 4-dehydrogenase Glycoprotein hormones alpha chain Lutropin subunit beta Polyprenol reductase Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Very-long-chain 3-oxoacyl-CoA reductase	A5PJS2 A6H7H3 E1BCQ0 E1BJY8 F6RUH3 P01190 P01217 P04651 P05185 P14893	CGA CYP17 CYP17A1 HSD17B12 HSD17B3 HSD3B LHB LOC789567 POMC SRD5A1 SRD5A2 SRD5A3
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Granulocyte-macrophage colony-stimulating factor Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene vav SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A140T878 A0A3Q1LK34 A0A3Q1M739 E1BCP6 E1BE66 F1MDQ5 F1MH16 F1MSH3 F1MXH7 F1MYM3 F1N339 P00517 P11052 P23726 P23727 P32871 P49875 P52173 P63103 Q08DN7 Q0IIE2 Q95115	CSF2 CSF2RB IL3 IL3RA IL5 IL5RA JAK2 MGF PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ
Deactivation of the beta-catenin transactivating complex	14-3-3 protein zeta/delta APC regulator of WNT signaling pathway Beta-catenin-interacting protein 1 C-terminal binding protein 1 Catenin beta-1 DNA helicase E3 ubiquitin-protein ligase XIAP Exportin 1 Histone deacetylase 1 Lymphoid enhancer binding factor 1 Polyubiquitin-B Polyubiquitin-C Protein chibby homolog 1 SRY-box transcription factor 13 SRY-box transcription factor 17 SRY-box transcription factor 3 SRY-box transcription factor 6 SRY-box transcription factor 7 TLE family member 1, transcriptional corepressor TLE family member 2, transcriptional corepressor TLE family member 3, transcriptional corepressor TLE family member 4, transcriptional corepressor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7 Transcription factor SOX-9 Transcription factor SOX Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein non-specific serine/threonine protein kinase	A0A3Q1LJY1 A0A3Q1LMC7 A0A3Q1LTE2 A0A3Q1LUX0 A0A3Q1M0P9 A0A3Q1M3K5 A0A3Q1M504 A0A3Q1MAN6 A0A3Q1MG64 A0A3Q1MN22 A0A3Q1MUX6 A0A3Q1MZ99 A0A3Q1NH21 E1BE98 E1BL97 F1MJS2 F1ML22 F1MLB2 F1N1F9 G3MWG5 P0CG53 P0CH28 P62992 P63048 P63103 Q0VCF8 Q0VCX4 Q32PJ8 Q5E9N2 Q8MJK1	AKT2 APC CBY CBY1 CHD8 CTBP1 CTNNB1 CTNNBIP1 HDAC1 LEF1 PGEA1 RPS27A SOX13 SOX17 SOX3 SOX4 SOX6 SOX7 SOX9 TCF7 TCF7L1 TCF7L2 TLE1 TLE2 TLE3 TLE4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XIAP XPO1 YWHAZ
HSF1 activation	14-3-3 protein epsilon Elongation factor 1-alpha 1 Heat shock factor protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Histone deacetylase 6 Prostaglandin E synthase 3 Transitional endoplasmic reticulum ATPase	A0A452DIU3 F1MQP3 G3X757 P62261 P68103 Q08DJ8 Q76LV1 Q76LV2	EEF1A EEF1A1 EF1A HDAC6 HSF1 HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB PTGES3 VCP YWHAE
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-3 Acetyl-CoA carboxylase kinase Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8 Cytochrome c oxidase subunit NDUFA4 Cytochrome c oxidase subunit NDUFA4 Cytochrome c DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutathione reductase Leucine rich pentatricopeptide repeat containing Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Protein kinase AMP-activated non-catalytic subunit beta 2 Protein kinase AMP-activated non-catalytic subunit gamma 2 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein A Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 SESN1 protein SURF1-like protein Serine/threonine-protein kinase mTOR Sestrin 3 Sestrin-2 TSC complex subunit 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Translational activator of cytochrome c oxidase I Uncharacterized protein glutaminase glutaminase	A0A0N4STN2 A0A140T894 A0A3Q1LKB8 A0A3Q1LTU9 A0A3Q1LYC8 A0A3Q1M6L2 A0A3Q1MM55 A0A3Q1MMW4 A0A3Q1MQS6 A0A3Q1MSS5 A0A3Q1MVT8 A1A4J8 A3KMZ6 A6H784 A7MBI2 A7Z057 A8E4L1 E1B986 E1BFB4 E1BH77 E1BHZ6 E1BJK7 E1BKZ1 E1BPX9 F1MBG5 F1MFJ7 F1MG06 F1MM79 F1MM99 F1MQV7 F1N5P2 F2Z4I1 G5E5G3 O62768 O97680 P00423 P00426 P00430 P04038 P13182 P58108 P62261 P62894 P63103 P68509 P68530 Q01321 Q08E62 Q0VC36 Q0VD29 Q17QQ1 Q17QU5 Q1JQA7 Q1RMH3 Q2LL38 Q2M2U3 Q2NKS2 Q3SX43 Q3SZ68 Q3SZI4 Q3T061 Q3T0D8 Q3T132 Q3ZBD7 Q58CN8 Q5BIS9 Q5E947 Q6QTG5 Q6QTG9 Q9BGI1 Q9BGI3	COII COX1 COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX3 COX4 COX4I1 COX5A COX6A1 COX6C COX7A2L COX7B COX7C COX7CP1 COXII CYC CYCS DDIT4 G6PD GBL GLS GLS2 GPI GSR LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LOC100296227 LOC783202 LRPPRC LST8 MLST8 MT-CO2 MTCO2 MTOR NDUFA4 PRDX1 PRDX2 PRDX5 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SCO1 SCO2 SCOD1 SESN1 SESN2 SESN3 SFN SLC38A9 SURF1 TACO1 TIGAR TSC1 TXN TXNRD1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase type 2 AKR1C4 protein ATP binding cassette subfamily B member 1 Albumin Corticosteroid-binding globulin Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Dihydrodiol dehydrogenase 3 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Prostaglandin F synthase 2 UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase	A0A140T897 A0A3Q1LWZ2 A0A3Q1LYU5 A0A3Q1LZ03 A0A3Q1M423 A0A3Q1MB23 A0A3Q1MIN6 E1BBB3 E1BF81 E1BG58 E1BJU8 E1BP71 F1MFF6 F1MNC0 F1MT58 F1N3U0 G3X6I4 M0QW04 M0QW14 M0QW25 P52897 P52898 Q29RV2 Q3T047 Q3ZBG2	ABCB1 AKR1C4 ALB CBG CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 HSD11B2 LOC100138004 LOC100138908 LOC100296421 LOC506594 LOC538060 LOC782061 LOC782884 LOC785762 SERPINA6 UGT1A6 UGT2B10
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Corticosteroid-binding globulin Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase steroid 11beta-monooxygenase steroid 11beta-monooxygenase steroid 11beta-monooxygenase	E1BF81 F1MG97 F1MU47 F1MWH3 F1N3U0 P00191 P01190 P05185 P14893	CBG CYP11B1 CYP17 CYP17A1 CYP21 CYP21A1 CYP21A2 HSD11B2 HSD3B LOC112449566 POMC SERPINA6
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase C-1-tetrahydrofolate synthase, cytoplasmic Dihydrofolate reductase Folate receptor 2 (Fetal) Folylpolyglutamate synthase Methylenetetrahydrofolate reductase Monofunctional C1-tetrahydrofolate synthase, mitochondrial Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase, mitochondrial Serine hydroxymethyltransferase Solute carrier family 25 member 32 methenyltetrahydrofolate cyclohydrolase methenyltetrahydrofolate cyclohydrolase	A0A140T872 A0A140T896 A0A3Q1MU29 A0A3Q1NGK6 A0A452DI11 A4FUD0 E1BDG9 E1BMG9 E1BNJ2 F1MWN5 G3X7X2 Q05B81 Q0VCN9 Q0VCR7 Q1RMT3 Q3SZ20	ALDH1L1 ALDH1L2 DHFR FOLR2 FPGS HCP1 MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS PCFT SHMT1 SHMT2 SLC19A1 SLC25A32 SLC46A1
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Neurotrophin-3 Tyrosine-protein kinase receptor	F1MYF9 G3N3T6 Q08DT3	NTF3 NTRK3 PLCG1
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1MPT9 A0MTF4 D8KXU9 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 Fgf4 HBGF-1 PLCG1
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MYF9 F1N6G8 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 HBGF-1 KL PLCG1
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 Fgf4 HBGF-1 PLCG1
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Artemin DOK4 protein Docking protein 1 Docking protein 2 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Glial cell derived neurotrophic factor Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene tyrosine-protein kinase receptor Ret RAP1 GTPase activating protein SH3 and multiple ankyrin repeat domains 3 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LNN8 A0A3Q1M0Y1 A0A3Q1M864 A0A3Q1MTG9 A0A3Q1N8H3 A0A452DJE2 A4IFA9 A4IFJ7 A5PKJ4 A6QLU3 A7MBB8 E1B7I9 E1BD76 E1BE66 E1BIM8 E1BKU1 F1MDQ5 F1MJE0 F1MP52 F1MRT5 F1MS00 F1MYF9 F1MYM3 F1N339 F1N7C3 F6S0Q2 G3MZM3 G3N3X9 G3X7B4 P00517 P23726 P23727 P32871 Q0IIE2 Q0VCR5 Q1RMW5 Q3SX40 Q3T0F9	ARTN DOK1 DOK2 DOK4 DOK5 DOK6 FRS2 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB10 GRB2 GRB7 IRS2 MAPK7 NRTN PDLIM7 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PRKACA PRKACB PTPN11 RAP1GAP RET SHANK3 SHC1 SHC3 SOS1 SRC
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk BCAR1 scaffold protein, Cas family member CRK like proto-onco, adaptor protein Cytoplasmic protein Cytoplasmic protein GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B RAS p21 protein activator 1 Rap guanine nucleotide exchange factor 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A140T878 A0A3Q1LXN8 A0A3Q1ME65 A0A3Q1ME99 A0A3Q1MQ07 A0A3Q1N3Z8 A5D7R9 A6H720 B1H0W5 E1BIM8 E1BMX0 E1BQ32 F1MGJ4 F1MX38 F1MYF9 F1MYM3 F1N339 F1N7C3 F1N7N8 G3N016 P23726 P23727 P32871 Q1LZB2 Q1RMW5 Q2KJ15 Q3T0F9 Q95115	BCAR1 CRK CRKL GRB2 GRB7 KRAS MGF NCK1 NCK2 NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PTPN11 RAPGEF1 RASA1 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 3-phosphoinositide-dependent protein kinase 1 GTPase NRas Protein kinase C beta type Protein kinase C delta type Protein kinase C RAS p21 protein activator 1 Sphingosine kinase 1 Tyrosine-protein kinase Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 small monomeric GTPase	A0A3Q1MRR6 A0A3Q1MSP9 A5D7R9 E1BIM8 E1BMX0 F1MQJ7 F1MWF1 F1MXZ6 F1MYF9 F1N7N8 P05126 P15691	KDR KRAS NRAS PDPK1 PLCG1 PRKCB PRKCB1 PRKCD PRKCZ RASA1 SPHK1 SRC VEGF VEGFA
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma C-type lectin domain containing 10A C-type lectin domain family 4 member D C-type lectin domain family 4 member E C-type lectin domain family 6 member A High affinity immunoglobulin epsilon receptor subunit gamma Mucin 15, cell surface associated Mucin 20, cell surface associated Mucin-1 Mucin-2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase VWFD domain-containing protein	A0A3Q1M2T0 A0A3Q1M633 A0A3Q1M6U9 A0A3Q1MHG9 A0A3Q1MMD9 A0A3S5ZPG9 A0JNB0 E1BHM0 E1BJL5 F1N261 F1N4H1 G5E5A7 Q3LUH2 Q9BDR7	CLEC10A CLEC4D CLEC4E CLEC6A DECTIN2 FCER1G FYN LOC789503 LYN MUC1 MUC15 MUC2 MUC20 PLCG2 SYK
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Integrin beta-2 Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type dynamin GTPase	A0A3Q1MIC9 A0A3Q1MMD9 A0A3Q1MZF3 A6QNL0 C4T7Z1 E1BJR7 F1MFI2 F1MNN7 G3MYD9 P17453 P32592 Q08DF4 Q2LGB7 Q6WCD5	BPI CD14 CD18 CD180 DNM1 DNM3 ITGAM ITGB2 LBP LY86 LY96 MD-2 PLCG2 PTPN4 TICAM2 TLR4 TRAM
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma B cell linker B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD19 molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides Growth factor receptor-bound protein 2 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Proto-oncogene vav SH3 domain containing kinase binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Stromal interaction molecule 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LKV0 A0A3Q1M535 A0A3Q1M739 A0A3Q1M839 A0A3Q1MFU0 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1N7P8 A0A3Q1NI55 A0A3Q1NIZ6 A0A3S5ZPA3 E1BE66 E1BKE7 F1MMQ7 F1MX21 F1N586 F1N7C3 G5E513 P23727 P40293 Q08DN7 Q08DV4 Q1LZB2 Q3T0F9 Q3ZC95	BLNK BTK CD19 CD22 CD79A CD79B DAPP1 GRB2 IGA ITPR1 ITPR2 ITPR3 MB-1 NCK1 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTPN6 SH3KBP1 SOS1 STIM1 SYK TRPC1 VAV1
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell CLL/lymphoma 10 C-type lectin domain containing 7A Caspase recruitment domain family member 9 Cell division cycle 34, ubiqiutin conjugating enzyme Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta MALT1 paracaspase Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappaB transcription factor p65 subunit Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TNF receptor-associated factor 6 Tyrosine-protein kinase Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LKU2 A0A3Q1LT51 A0A3Q1M118 A0A3Q1M7T8 A0A3Q1MMD9 A0A3Q1MRR6 A0A452DI44 A0A452DIY4 A1XG22 A2VDU3 A7MBA2 E1B7Z0 E1BD83 E1BIM8 F1MBI1 F1MBS7 F1MKW9 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N2F3 F1N4D3 F1N6Z0 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QJ6 Q17QP9 Q1RMX2 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA10 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCC3 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	BCL10 CARD9 CDC34 CHUK CLEC7A CUL1 FBXW11 IKBKB IKBKG IKKA MALT1 MAP3K7 NEMO NFKB1 NFKBIA PLCG2 PRKCD PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RELA RPS27A SKP1 SKP1A SRC SUG1 TAB1 TAB2 TAB3 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 bIkBa
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma BOLA-DQA1 protein BoLA-DR-alpha CD101 molecule Cytoplasmic protein FYB protein GRB2 related adaptor protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Linker for activation of T cells Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A3Q1LSY0 A0A3Q1M088 A0A3Q1M0G8 A0A3Q1M3D2 A0A3Q1MMD9 A0A3Q1MT21 A0A3Q1MTF5 A6H6Y1 A6QQE7 A7YWJ7 A7Z039 E1BKA6 E1BLZ1 E1BMP9 F1MJK4 F1MJU5 F1ML60 F1MYF9 F1MZ60 F1N0X9 G3MWT2 G8JL01 Q08DS6 Q08E52 Q0VCU4 Q1LZB2 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD101 CD247 CD3D CD3E CD3G CD4 DYB FYB FYB1 GRAP2 HLA-DRA ITK LAT LCK LCP2 LOC100848815 NCK1 PAK1 PAK2 PAK3 PLCG1 PLCG2 TRAV29-1 ZAP70
Role of phospholipids in phagocytosis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 5'-3' exonuclease PLD3 Fc fragment of IgG receptor IIb Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phospholipase D family member 4 Phospholipase Phospholipase Phospholipid phosphatase 4 Phospholipid phosphatase 5 Protein kinase C delta type T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phospholipase A2	A0A3Q1LJY0 A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1M3L6 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1MRR6 A0A3S5ZP99 E1BB89 F1MH11 F1MHH9 F1MXQ6 F1MYF9 F1MYM3 G3N0V0 G8JL01 P23726 P23727 P32871 P79107 Q0VCU4 Q2KJJ8	CD247 CD3G FCGR1A FCGR2B FCGR3 FCGR3A FCGRIII PIK3CA PIK3CB PIK3R1 PIK3R2 PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPP4 PLPP5 PRKCD SYK

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