HS-GAG biosynthesis
|
|
|
- AGRN
- EXT1
- EXT2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- HS2ST1
- HS3ST1
- HS3ST2
- HS3ST3A1
- HS3ST3B1
- HS3ST5
- HS3ST6
- HS6ST2
- HS6ST3
- NDST1
- NDST2
- NDST4
- SDC1
- SDC2
- SDC4
- SLC35D2
|
|
HS-GAG degradation
|
|
|
- AGRN
- GLB1
- GLB1L
- GLB1L2
- GPC1
- GPC2
- GPC3
- GPC4
- GPC5
- GUSB
- HPSE
- HPSE2
- IDS
- IDUA
- NAGLU
- SDC1
- SDC2
- SDC4
- SGSH
|
|
Glyoxylate metabolism and glycine degradation
|
|
|
- AGXT
- AGXT2
- ALDH4A1
- DAO
- DHDPSL
- GNMT
- GOT2
- GRHPR
- HAO1
- HOGA1
|
|
Separation of Sister Chromatids
|
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome non-ATPase regulatory subunit 2
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome non-ATPase regulatory subunit 4
- 26S proteasome non-ATPase regulatory subunit 5
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 9
- 26S proteasome regulatory subunit 6B
- 26S proteasome regulatory subunit 7
- 26S proteasome regulatory subunit 8
- AT-hook containing transcription factor 1
- Alpha isoform of regulatory subunit A, protein phosphatase 2
- Anaphase promoting complex subunit 1
- Anaphase promoting complex subunit 7
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 15
- Anaphase-promoting complex subunit 16
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit CDC26
- Aurora kinase
- B9 domain-containing protein 2
- BUB1 mitotic checkpoint serine/threonine kinase B
- BUB1 protein
- Baculoviral IAP repeat-containing protein 5
- Borealin
- CAP-Gly domain containing linker protein 1
- CENPI protein
- CENPP protein
- Cell division cycle 16
- Cell division cycle 20
- Cell division cycle associated 5
- Cell division cycle protein 23 homolog
- Cell division cycle protein 27 homolog
- Centromere protein C
- Centromere protein E
- Centromere protein F
- Centromere protein H
- Centromere protein K
- Centromere protein L
- Centromere protein M
- Centromere protein N
- Centromere protein O
- Centromere protein Q
- Centromere protein S
- Centromere protein T
- Cohesin subunit SA
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic linker associated protein 1
- Cytoplasmic linker associated protein 2
- Cytoskeleton associated protein 5
- DNA excision repair protein ERCC-6-like
- DSN1 component of MIS12 kinetochore complex
- Double-strand-break repair protein rad21 homolog
- Dynein cytoplasmic 1 heavy chain 1
- Dynein light chain 1, cytoplasmic
- Dynein light chain 2, cytoplasmic
- Dynein light intermediate chain
- Dynein light intermediate chain
- E2 ubiquitin-conjugating enzyme
- Exportin 1
- Histone H3-like centromeric protein A
- Histone deacetylase 8
- Inner centromere protein
- Integrin subunit beta 3 binding protein
- Kinesin-like protein
- Kinetochore associated 1
- Kinetochore protein NDC80
- Kinetochore protein Spc24
- Kinetochore protein Spc25
- Kinetochore scaffold 1
- Microtubule-associated protein RP/EB family member 1
- Mitotic arrest deficient 1 like 1
- Mitotic arrest deficient 2 like 1
- Mitotic checkpoint protein BUB3
- NDE1 protein
- NSL1 protein
- NUF2 component of NDC80 kinetochore complex
- NUP43 protein
- Nuclear distribution protein nudE-like 1
- Nuclear migration protein nudC
- Nuclear pore complex protein Nup85
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein
- Nucleoporin 133
- Nucleoporin 160
- Nucleoporin 37
- Nucleoporin SEH1
- PDS5 cohesin associated factor A
- PDS5 cohesin associated factor B
- Platelet-activating factor acetylhydrolase IB subunit alpha
- Polyamine-modulated factor 1
- Polyubiquitin-B
- Polyubiquitin-C
- Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14
- Proteasome 26S subunit, ATPase 3
- Proteasome 26S subunit, ATPase 6
- Proteasome activator complex subunit 1
- Proteasome activator complex subunit 2
- Proteasome activator subunit 4
- Proteasome inhibitor PI31 subunit
- Proteasome subunit alpha type-1
- Proteasome subunit alpha type-2
- Proteasome subunit alpha type-3
- Proteasome subunit alpha type-4
- Proteasome subunit alpha type-5
- Proteasome subunit alpha type-6
- Proteasome subunit alpha type-7
- Proteasome subunit alpha type
- Proteasome subunit beta type-10
- Proteasome subunit beta type-2
- Proteasome subunit beta type-3
- Proteasome subunit beta type-4
- Proteasome subunit beta type-5
- Proteasome subunit beta type-6
- Proteasome subunit beta type-8
- Proteasome subunit beta type-9
- Proteasome subunit beta
- Proteasome subunit beta
- Protein MIS12 homolog
- Protein SEC13 homolog
- Protein Spindly
- Protein phosphatase 2 scaffold subunit Abeta
- Protein zwilch homolog
- RAN binding protein 2
- RCC2 protein
- Ran GTPase activating protein 1
- STAG1 cohesin complex component
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
- Shugoshin 1
- Shugoshin 2
- Small ribosomal subunit protein eS27
- Spindle and kinetochore-associated protein 1
- Spindle and kinetochore-associated protein 2
- Structural maintenance of chromosomes protein 1A
- Structural maintenance of chromosomes protein
- Ubiquitin-conjugating enzyme E2 C
- Ubiquitin-conjugating enzyme E2 D1
- Ubiquitin-conjugating enzyme E2 S
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
- WAPL cohesin release factor
- ZW10 interacting kinetochore protein
- ZW10, kinetochore associated, homolog (Drosophila)
- non-specific serine/threonine protein kinase
- separase
|
|
- AHCTF1
- ANAPC1
- ANAPC10
- ANAPC11
- ANAPC15
- ANAPC16
- ANAPC2
- ANAPC4
- ANAPC5
- ANAPC7
- ANAPC8
- APITD1
- AURKB
- B9D2
- BIRC5
- BUB1
- BUB1B
- BUB3
- CCDC99
- CDC16
- CDC20
- CDC23
- CDC26
- CDC27
- CDCA5
- CDCA8
- CENPC
- CENPE
- CENPF
- CENPH
- CENPI
- CENPK
- CENPL
- CENPM
- CENPO
- CENPP
- CENPQ
- CENPS
- CENPT
- CKAP5
- CLASP1
- CLASP2
- CLIP1
- DNCL1
- DSN1
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- ERCC6L
- ESPL1
- FAAP16
- HDAC8
- INCENP
- ITGB3BP
- KIF2B
- KNL1
- KNTC1
- LIS1
- MAD1L1
- MAD2L1
- MAPRE1
- MCM21R
- MHF1
- MIS12
- NDC80
- NDE1
- NDEL1
- NSL1
- NUDC
- NUF2
- NUP107
- NUP133
- NUP160
- NUP37
- NUP43
- NUP85
- NUP98
- PAFAH1B1
- PDS5A
- PDS5B
- PLK1
- PMF1
- PPP1CC
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5D
- PPP2R5E
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- RAD21
- RANBP2
- RANGAP1
- RCC2
- RPS27
- RPS27A
- SCC1
- SEC13
- SEC13L1
- SEH1L
- SGO1
- SGO2
- SKA1
- SKA2
- SMC1
- SMC1A
- SMC1L1
- SMC3
- SPBC25
- SPC24
- SPC25
- SPDL1
- STAG1
- STAG2
- SUG1
- TAOK1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBCH10
- UBE2C
- UBE2D1
- UBE2E1
- UBE2S
- WAPL
- XPO1
- ZW10
- ZWILCH
- ZWINT
|
|
Mitotic Prometaphase
|
|
|
- AHCTF1
- APITD1
- AURKB
- B9D2
- BIRC5
- BUB1
- BUB1B
- BUB3
- CCDC99
- CDC20
- CDCA8
- CENPC
- CENPE
- CENPF
- CENPH
- CENPI
- CENPK
- CENPL
- CENPM
- CENPO
- CENPP
- CENPQ
- CENPS
- CENPT
- CKAP5
- CLASP1
- CLASP2
- CLIP1
- DNCL1
- DSN1
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- ERCC6L
- FAAP16
- INCENP
- ITGB3BP
- KIF2B
- KNL1
- KNTC1
- LIS1
- MAD1L1
- MAD2L1
- MAPRE1
- MCM21R
- MHF1
- MIS12
- NDC80
- NDE1
- NDEL1
- NSL1
- NUDC
- NUF2
- NUP107
- NUP133
- NUP160
- NUP37
- NUP43
- NUP85
- NUP98
- PAFAH1B1
- PLK1
- PMF1
- PPP1CC
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5D
- PPP2R5E
- RANBP2
- RANGAP1
- RCC2
- RPS27
- SEC13
- SEC13L1
- SEH1L
- SGO1
- SGO2
- SKA1
- SKA2
- SPBC25
- SPC24
- SPC25
- SPDL1
- TAOK1
- XPO1
- ZW10
- ZWILCH
- ZWINT
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Bicarbonate transporters
|
|
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- AHCYL2
- SLC4A1
- SLC4A10
- SLC4A2
- SLC4A3
- SLC4A4
- SLC4A5
- SLC4A7
- SLC4A8
- SLC4A9
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Aryl hydrocarbon receptor signalling
|
|
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- AHR
- AIP
- ARNT
- ARNT2
- HSP90AB1
- HSPC3
- HSPCB
- PTGES3
|
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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
|
|
|
- AIK
- AIRK1
- ANAPC1
- ANAPC10
- ANAPC11
- ANAPC15
- ANAPC16
- ANAPC2
- ANAPC4
- ANAPC5
- ANAPC7
- ANAPC8
- ARK1
- AURA
- AURKA
- AURKB
- AYK1
- BTAK
- CDC16
- CDC20
- CDC23
- CDC26
- CDC27
- FZR1
- IAK1
- PLK1
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- RB1
- RPS27A
- SKP2
- STK15
- STK6
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBCH10
- UBE2C
- UBE2D1
- UBE2E1
- UBE2S
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Regulation of TP53 Activity through Phosphorylation
|
|
|
- AIK
- AIRK1
- ARK1
- ATM
- ATR
- ATRIP
- AURA
- AURKA
- AURKB
- AYK1
- BARD1
- BLM
- BRCA1
- BRIP1
- BTAK
- CCNA1
- CCNA2
- CDK2
- CDK5
- CDK5R
- CDK5R1
- CDKN2
- CDKN5
- CHEK2
- CK2A1
- CK2N
- CSNK2A1
- CSNK2A2
- CSNK2B
- DNA2
- DYRK2
- EXO1
- HIPK1
- HIPK2
- HUS1
- IAK1
- KAT5
- MAPK11
- MAPK14
- MAPKAPK5
- MDM2
- MRE11
- NBN
- NCK5A
- NIR
- NOC2L
- NUAK1
- PIN1
- PLK3
- PRKAA1
- PRKAA2
- PRKAB1
- PRKAB2
- PRKAG1
- PRKAG2
- PRKAG3
- PSSALRE
- RAD1
- RAD17
- RAD50
- RAD9A
- RAD9B
- RBBP8
- RFC2
- RFC3
- RFC5
- RHNO1
- RMI1
- RMI2
- RPA1
- RPA2
- RPA3
- RPS27A
- SSRP1
- STK11
- STK15
- STK6
- SUPT16H
- TAF1
- TAF10
- TAF11
- TAF12
- TAF15
- TAF2
- TAF3
- TAF4
- TAF4B
- TAF5
- TAF6
- TAF7L
- TAF9
- TAF9B
- TBP
- TOP3A
- TOPBP1
- TP53
- TP53INP1
- TP53RK
- TPX2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WRN
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FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
|
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- AIK
- AIRK1
- ARK1
- AURA
- AURKA
- AYK1
- BTAK
- CUL1
- FBXL18
- FBXL7
- IAK1
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- RPS27A
- SKP1
- SKP1A
- STK15
- STK6
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Transcriptional and post-translational regulation of MITF-M expression and activity
|
|
|
- AIMP2
- CREBBP
- DARS1
- EEF1E1
- EPRS1
- ERK2
- GSK3B
- HINT1
- IARS
- IARS1
- JTV1
- KARS1
- KIT
- KITLG
- LARS1
- MAPK1
- MAPK3
- MARS1
- MITF
- PRKM1
- QARS
- QARS1
- RARS
- RARS1
- RPS6KA1
- SCF
- WNT3A
- XPO1
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|
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
|
|
|
- AJUBA
- CUL2
- EGLN1
- EGLN2
- EGLN3
- ELOC
- EPAS1
- HIF1A
- HIF3A
- JUB
- LIMD1
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA8
- PSMB1
- PSMB10
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMB8
- PSMB9
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME4
- PSMF1
- RPS27A
- SUG1
- TCEB1
- TCEB2
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5B
- UBE2D1
- UBE2D2
- UBE2D3
- WTIP
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Interconversion of nucleotide di- and triphosphates
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|
|
- AK1
- AK2
- AK3L1
- AK4
- AK5
- AK6
- AK7
- AK8
- AK9
- CINAP
- CMPK
- CMPK1
- CTPS
- CTPS1
- CTPS2
- DCTD
- DUT
- GSR
- GUK
- GUK1
- NME1-2
- NME2
- NME3
- NME4
- NUDT13
- RRM1
- RRM2
- RRM2B
- TXN
- TXNRD1
- TYMS
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Glutathione conjugation
|
|
|
- AKR1A1
- ESD
- GSTA1
- GSTA2
- GSTA4
- GSTA5
- GSTK1
- GSTM1
- GSTM3
- GSTM4
- GSTO2
- GSTP1
- GSTT1
- HPGDS
- LOC100295687
- MGST1
- MGST2
- MGST3
|
|
Fructose biosynthesis
|
|
|
|
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Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
|
|
|
- AKR1C4
- CBR1
- CYP8
- HPGDS
- LOC506594
- LOC538060
- LOC782061
- LOC782884
- LOC785762
- PTGDS
- PTGES
- PTGES2
- PTGES3
- PTGIS
- PTGS1
- PTGS2
- TBXAS1
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|
HSF1-dependent transactivation
|
|
|
- AKT1S1
- CAMK2A
- CAMK2B
- CAMK2D
- CRYA2
- CRYAB
- DNAJB1
- GBL
- HSBP1
- HSC70
- HSF1
- HSP70-1
- HSP90A
- HSP90AA1
- HSP90AB1
- HSPA1A
- HSPA1L
- HSPA8
- HSPB8
- HSPC3
- HSPCA
- HSPCB
- LST8
- MLST8
- MTOR
- RPTOR
|
|
Deactivation of the beta-catenin transactivating complex
|
|
|
- AKT2
- APC
- CBY
- CBY1
- CHD8
- CTBP1
- CTNNB1
- CTNNBIP1
- HDAC1
- LEF1
- PGEA1
- RPS27A
- SOX13
- SOX17
- SOX3
- SOX4
- SOX6
- SOX7
- SOX9
- TCF7
- TCF7L1
- TCF7L2
- TLE1
- TLE2
- TLE3
- TLE4
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- XIAP
- XPO1
- YWHAZ
|
|
HDL remodeling
|
|
|
- ALB
- APOA1
- APOC2
- APOC3
- APOE
- LCAT
- LIPG
- PLTP
|
|
Scavenging of heme from plasma
|
|
|
- ALB
- CD163
- HBA
- HBB
- HPX
- LRP1
- M130
|
|
Glutamate and glutamine metabolism
|
|
|
- ALDH18A1
- FAM80B
- GLS
- GLS2
- GLUD1
- GLUL
- GOT2
- OAT
- PYCR1
- PYCR2
- PYCR3
- PYCRL
- RIMKLA
- RIMKLB
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|
Metabolism of folate and pterines
|
|
|
- ALDH1L1
- ALDH1L2
- DHFR
- FOLR2
- FPGS
- HCP1
- MTHFD1
- MTHFD1L
- MTHFD2
- MTHFD2L
- MTHFR
- MTHFS
- PCFT
- SHMT1
- SHMT2
- SLC19A1
- SLC25A32
- SLC46A1
|
|
RND1 GTPase cycle
|
|
|
- ALDH3A2
- ANKRD26
- ARHGAP35
- ARHGAP5
- CAV1
- CCDC88A
- CPD
- DEPDC1B
- DLG5
- DSP
- DST
- EPHA2
- EPSTI1
- FAM135A
- FAM83B
- FLOT2
- FRS2
- FRS3
- GRB7
- KIDINS220
- KIF14
- PIK3R1
- PIK3R2
- PKP4
- PLEKHG5
- PLXNA1
- PTPN13
- RASAL2
- RBM39
- RBMX
- RHO6
- RND1
- STIP1
- STMN2
- TFRC
- TMEM59
- TXNL1
- UBXN11
- VANGL1
- VANGL2
- WDR6
|
|
Gluconeogenesis
|
|
|
- ALDOA
- ALDOB
- ALDOC
- ENO2
- ENO3
- ENO4
- FBP1
- FBP2
- G6PC
- G6PC1
- G6PC2
- G6PC3
- GAPD
- GAPDH
- GAPDHS
- GPI
- PC
- PCK1
- PCK2
- PGAM1
- PGAM2
- PGK1
- SLC37A1
- SLC37A2
- SLC37A4
- TPI1
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Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
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- ALG1
- ALG12
- ALG14
- ALG2
- ALG3
- ALG6
- ALG8
- ALG9
- DPAGT1
- LOC107132045
- MPDU1
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