Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Source Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Displaying entries 76 - 100 of 1840 in total
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID
Burkholderia cepacia Lectin-like proteins (adhesin) Gb2 (Galabiosylceramide) Diosylceramides Sputa of cystic fibrosis patients Gal(a1-4)Gal(b1-1)Cer Binding 8606110
Bordetella pertussis CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) Lactosylceramide (Lactocerebroside) Diosylceramides Respiratory ciliated cells, Alveolar macrophages Gal(b1-4)Glc(b1-1)Cer Binding 8514379
Escherichia coli S-fimbriae (SfaA) Lactosylceramide (Lactocerebroside) Diosylceramides Brain endothelial cells Gal(b1-4)Glc(b1-1)Cer Binding 8098039
Escherichia coli P-fimbriae Gb2 (Galabiosylceramide) Diosylceramides Urine Gal(a1-4)Gal(b1-1)Cer Binding 16564136
Pseudomonas aeruginosa Type 4-pili Lactosylceramide (Lactocerebroside) Diosylceramides Epithelial cells Gal(b1-4)Glc(b1-1)Cer Binding 9224879
Escherichia coli P-pili Gb2 (Galabiosylceramide) Diosylceramides Epithelial cells in human urinary tract Gal(a1-4)Gal(b1-1)Cer Binding 9007266
Bordetella pertussis Pertussis toxin Lactosylceramide (Lactocerebroside) Diosylceramides Human cilia of the respiratory epithelium Gal(b1-4)Glc(b1-1)Cer Binding 1729677
Saccharomyces cerevisiae Unknown Lactosylceramide (Lactocerebroside) Diosylceramides Human lung, Human polymorphonuclear leukocytes, Human glioma brain cells Gal(b1-4)Glc(b1-1)Cer Binding 2194958
Propionibacterium granulosum Unknown Lactosylceramide (Lactocerebroside) Diosylceramides Whole dog small intestine Gal(b1-4)Glc(b1-1)Cer Binding 2452754
Helicobacter pylori 35S-labeled or 125I-labeled proteins Lactosylceramide (d18:1-16:0/24:1) Diosylceramides Human granulocytes, Human erythrocytes Gal(b1-4)Glc(b1-1)Cer Not Binding 9499377
Helicobacter pylori 35S-labeled or 125I-labeled proteins Lactosylceramide (d18:1-h16:0/t18:0-h24:0/t18:0-h16:0) Diosylceramides Dog small intestine Gal(b1-4)Glc(b1-1)Cer Binding 9499377
Escherichia coli PapG alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose Disaccharides Uroepithelial cells Gal(a1-4)Gal Binding 2886993
Escherichia coli K1 unnamed ligand Disaccharides Endothelial cells GlcNAc(b1-4)GlcNAc Binding 16564136
Clostridium botulinum Progenitor toxin (type A) Lactose Disaccharides Intestine-407 cells Gal(b1-4)Glc Binding 15850798
Clostridium botulinum Progenitor toxin (type A) N-acetyllactosamine (LacNAc) Disaccharides Intestine-407 cells Gal(b1-4)GlcNAc Binding 15850798
Clostridium botulinum Botulinum neurotoxin (16S) Lactose Disaccharides Intestinal epithelial cells (T84) Gal(b1-4)Glc Binding 17156748
Clostridium botulinum HA Lactose Disaccharides Intestinal epithelial cells (T84) Gal(b1-4)Glc Binding 17156748
Norovirus Unknown Blood group H antigen Disaccharides Saliva Fuc(a1-2)Gal Binding 18701592
Escherichia coli P-fimbriae Gal alpha 1-4 Gal-containing glicolipids Glycolipids Pyelonephritis patients Gal(a1-4)Gal Binding 8574698
Clostridium difficile Toxin A α-Gal on Fab of IgA(κ) MAb Glycoproteins Mouse Gal Binding 9573079
Clostridium difficile Toxin A α-Gal on Fab of IgM(λ) MAb Glycoproteins Mouse Gal Binding 9573079
Clostridium difficile Toxin A β-Gal on Fab of IgG3(λ) MAb Glycoproteins Mouse Gal Binding 9573079
Norovirus Unknown Blood group B antigen (B-tri-HSA) Glycoproteins Human serum albumin Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE Binding 19054801
Norovirus Unknown Blood group A antigen (A-tri-HSA) Glycoproteins Human serum albumin GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE Binding 19054801
Norovirus Unknown Blood group H1 antigen (HSA) Glycoproteins Human serum albumin Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD Binding 19054801

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