GPVI-mediated activation cascade

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type IADPGPVI:FceRI gamma:FYN:LYN:Collagen type IGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:SYKSYKGPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:p-Y348-SYKp-Y348-SYKp-Y348-SYK:VAV familyVAV familyp-Y348-SYK:p-VAV familyGTPGDPVAV1 Rho/Rac effectors:GDPVAV1 Rho/Rac effectors:GTPVAV2 Rho/Rac effectors:GDPVAV2 Rho/Rac effectors:GTPVAV3 Rho/Rac effectors:GDPVAV3 Rho/Rac effectors:GTPLATp-Y200,Y220-LATLCP2p-SLP-76PLCG2p-PLCG2VAV1,2,3p-SLP-76:VAVPIP2IP3DAGPIP3:VAV1,2,3PIP3VAV family:PIP2PI3K gammaPI3K betaPDK1PDK1:PIP3PRKCZPDPK1:PIP3:PRKCZPDPK1:PIP3:p-T410-PRKCZSHP1,SHP2G6B:PTPN6,PTPN11G6BPDPNCLEC1B dimer:PDPNCLEC1B dimerp-Y7-CLEC1B dimer:PDPNp-Y7-CLEC1B dimer:PDPN:SYK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025