NOTCH3 Activation and Transmission of Signal to the Nucleus

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
DLL1DLL1:NOTCH3NOTCH3JAG1:NOTCH3JAG1JAG2:NOTCH3JAG2DLL4DLL4:NOTCH3UbUb-DLL/JAG:NOTCH3DLL/JAG:NOTCH3NEXT3Ub-DLL/JAG:NOTCH3(40-1628)NICD3TM3TACC3NICD3:TACC3EGF:p-6Y-EGFR dimerEGF:p-6Y-EGFR dimer:NICD3ATPp-Y-NICD3ADPNEXT3,NICD3NEXT3,NICD3:WWP2WWP2Ub-NEXT3,Ub-NICD3:WWP2NICD3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025