Downregulation of SMAD2/3:SMAD4 transcriptional activity

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying entries 1 - 10 of 13 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O09106 Histone deacetylase 1
  • Hdac1
view
P0CG49 Polyubiquitin-B
  • Ubb
view
P11103 Poly [ADP-ribose] polymerase 1
  • Adprp
  • Adprt
  • Adprt1
  • Parp1
view
P70398 Ubiquitin carboxyl-terminal hydrolase 9X
  • Fafl
  • Fam
  • Usp9x
view
P97471 Mothers against decapentaplegic homolog 4
  • Dpc4
  • Madh4
  • Smad4
view
Q60665 Ski-like protein
  • Skil
  • Skir
  • Sno
view
Q60698 Ski oncogene
  • Ski
view
Q60974 Nuclear receptor corepressor 1
  • Ncor1
  • Rxrip13
view
Q62432 Mothers against decapentaplegic homolog 2
  • Madh2
  • Madr2
  • Smad2
view
Q8CFI0 E3 ubiquitin-protein ligase NEDD4-like
  • Kiaa0439
  • Nedd4b
  • Nedd4l
view

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025