GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **557** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Hedgehog 'off' state	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Fuzzy planar cell polarity protein G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Intraflagellar transport 140 Intraflagellar transport 52 homolog (Chlamydomonas) Intraflagellar transport 88 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 57 homolog Kinesin family member 7 Kinesin-like protein OFD1 centriole and centriolar satellite protein Patched 1 Protein inturned Protein kinase cAMP-dependent type I regulatory subunit beta Protein smoothened RPGRIP1 like Suppressor of fused homolog TTC21B protein Tubby-like protein WD repeat domain 19 WD repeat-containing protein 35 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase	A0A3Q1LM07 A0A3Q1LTC8 A0A3Q1LWP8 A0A3Q1MA58 A0A3Q1MCI6 A0A3Q1MDV1 A0A3Q1MNB3 A0A452DIR3 A0A452DJE2 A6H727 A7MB60 E1B7Q4 E1B860 E1B9K3 E1BBF8 E1BE57 E1BHU9 E1BJB4 E1BKE3 E1BM79 E1BQ12 F1MCY1 F1MDL2 F1MG59 F1MJV4 F1MPC9 F1N215 F1N7S0 G3N1D5 P00514 P00515 P00517 P19754 Q2YDN1 Q32KR5	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 FUZ GLI1 GLI2 GLI3 GPR161 IFT122 IFT140 IFT52 IFT57 IFT88 INTU KIF3A KIF7 OFD1 PDZD6 PRKACA PRKACB PRKAR1A PRKAR1B PRKAR2A PTCH1 RPGRIP1L SMO SUFU TTC21B TULP3 WDR19 WDR35	Bos taurus (cattle)
Hedgehog 'on' state	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division cycle 73 Cullin 3 DAZ interacting zinc finger protein 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase EvC ciliary complex subunit 1 EvC ciliary complex subunit 2 G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Kinesin family member 7 Patched 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein numb homolog Protein smoothened Serine/threonine-protein kinase ULK3 Speckle type BTB/POZ protein like Speckle-type POZ protein Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LJ39 A0A3Q1LM07 A0A3Q1M267 A0A3Q1MDV1 A0A3Q1MSE5 A0A452DI44 A0A452DIY4 A6H727 A7MBA2 E1B8G1 E1BD83 E1BE57 E1BES3 E1BIN5 E1BPQ8 F1MBI1 F1MCY1 F1MGQ5 F1MLS5 F1MLV1 F1MQQ1 F1MWE0 F1MXE4 F1MYH8 F1N215 F1N332 F1N6Z0 G3N1D5 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q0VCW1 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q2YDN1 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CDC73 CUL3 DZIP1 EVC EVC2 GLI1 GLI2 GLI3 GPR161 ITCH KIF7 NUMB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTCH1 RPS27A SMO SMURF1 SMURF2 SPOP SPOPL SUFU SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ULK3	Bos taurus (cattle)
Hedgehog ligand biogenesis	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Derlin Endoplasmic reticulum lectin Endoplasmic reticulum lectin Hedgehog acyltransferase Hedgehog protein Hedgehog protein Hedgehog protein Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein disulfide-isomerase RING-type E3 ubiquitin transferase SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1NEJ8 A0A452DI44 A0A452DIY4 A7MBA2 E1BAK9 E1BD83 F1MBI1 F1MFP2 F1MGJ5 F1MGK3 F1MLV1 F1MM97 F1MWE0 F1MX65 F1MXE4 F1MYH8 F1N6Z0 F6PVF9 F6Q9Q9 F6QA78 G3X757 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	DERL2 DHH ERLEC1 HHAT IHH OS9 P4HB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SEL1L SHH SUG1 SYVN1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP	Bos taurus (cattle)
Heme degradation	ABC-type glutathione-S-conjugate transporter Albumin Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Flavin reductase (NADPH) Glutathione S-transferase A2 Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Heme oxygenase 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member UDP-glucuronosyltransferase heme oxygenase (biliverdin-producing)	A0A140T897 A0A3Q1M423 A0A3Q1MEC8 A0A3Q1MQ83 A0A3S5ZP51 B2D1N9 E1BKD8 F1MIP7 F1MTY9 F1MX44 F1MYV0 O18879 P52556 P80425 Q5E9F2 Q8HXQ5	ABCC1 ABCC2 ABCG2 ALB BLVRA BLVRB FABP1 GSTA1 GSTA2 GSTA5 HMOX1 HMOX2 MRP1 SCAN SLCO1B3 SLCO2B1 UGT1A6	Bos taurus (cattle)
Heme signaling	Apolipoprotein A-I Apolipoprotein B BTB domain and CNC homolog 1 Exportin 1 Hemoglobin subunit alpha Hemoglobin subunit beta Lymphocyte antigen 96 MAF bZIP transcription factor K Progesterone receptor membrane component 2 Proton-coupled folate transporter Toll-like receptor 4	C4T7Z1 E1BB01 E1BE98 E1BJL3 E1BNR0 F6QJJ8 P01966 P02070 P15497 Q05B81 Q6WCD5	APOA1 APOB BACH1 HBA HBB HCP1 LY96 MAFK MD-2 PCFT PGRMC2 SLC46A1 TLR4 XPO1	Bos taurus (cattle)
Highly calcium permeable nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Cholinergic receptor nicotinic alpha 6 subunit Cholinergic receptor nicotinic beta 2 subunit Cholinergic receptor nicotinic beta 3 subunit Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit beta-4	A0A3Q1MJN8 E1BHK0 F1MC93 F1MF30 F1MQ06 F1MYI7 F1N4T3 P02709 Q8SPU7	CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNB2 CHRNB3 CHRNB4	Bos taurus (cattle)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Cholinergic receptor nicotinic alpha 6 subunit Cholinergic receptor nicotinic alpha 9 subunit Cholinergic receptor nicotinic beta 2 subunit Cholinergic receptor nicotinic beta 3 subunit Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-7 Neuronal acetylcholine receptor subunit beta-4	A0A3Q1MJN8 A6QPI7 E1BHK0 F1MC93 F1MDD1 F1MF30 F1MQ06 F1MYI7 F1N4T3 P02709 Q8SPU7	CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB2 CHRNB3 CHRNB4	Bos taurus (cattle)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Acetylcholine receptor subunit delta Acetylcholine receptor subunit epsilon Acetylcholine receptor subunit gamma Cholinergic receptor nicotinic beta 2 subunit Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-4	A0A3Q1MJN8 E1BHK0 F1MC93 F1MYI7 P02715 P04759 P13536	CHRNA3 CHRNA4 CHRNB2 CHRNB4 CHRND CHRNE CHRNG	Bos taurus (cattle)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormone subunit alpha 2 Glycoprotein hormone subunit beta 5 Glycoprotein hormones alpha chain Gonadotropin releasing hormone 2 Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin Thyrotropin receptor Thyrotropin subunit beta	A0A0F7RPV8 A0A140T893 A0A3Q1M7J7 E1BD70 F1MT42 F1N4F6 P01217 P01223 P04651 P04837 P32236 Q0VBW7	CGA FSHB FSHR GNRH1 GNRH2 GNRHR GPA2 GPB5 GPHA2 GPHB5 LHB LHCGR TSHB TSHR	Bos taurus (cattle)
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	A0A3Q1LP80 E1BKX1 F1MY60 F1MZD4 F1N1R2	ABCC5 CEMIP DERPC HAS1 HAS2	Bos taurus (cattle)	G35674CY
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase-2 Hyaluronidase Hyaluronidase Lymphatic vessel endothelial hyaluronic acid receptor 1 Stabilin 2	A0A3Q1MJE8 A0A3Q1NH73 A3KMY8 F1MQT9 F1MSK8 F1MYW1 H7BWW2 Q0V8R6 Q3SYS6 Q6UC88 Q8SQG8	CD44 CHP CHP1 CRSBP1 GUSB HEXA HEXB HMMR HYAL1 HYAL2 HYAL3 LYVE1 STAB2 XLKD1	Bos taurus (cattle)	G35674CY
Hydrolysis of LPC	Cytosolic phospholipase A2 Lysosomal phospholipase A and acyltransferase Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1	A0A3Q1LYR5 A4IFJ5 F1MG30 F1MNU5 Q8WMP9 Q9GL30	CPLA2 LYPLA3 PLA2G15 PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLBD1	Bos taurus (cattle)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LLQ7 E1B8P9 E1BCP6 F1MXR5 F1N0D6 P07353 P46196	ERK2 IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 PRKM1	Bos taurus (cattle)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin 1 Cardiotrophin like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Interleukin 6 cytokine family signal transducer LIF receptor subunit alpha Leukemia inhibitory factor Oncostatin M Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	E1BAT3 E1BCP6 E1BD36 E1BD91 E1BFH9 F1MCX4 F1MLR4 F1N0D6 F1N366 G3MXT9 Q27956	CLCF1 CNTF CNTFR CTF1 IL6ST JAK1 JAK2 LIF LIFR OSM TYK2	Bos taurus (cattle)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform phosphatidylinositol-4,5-bisphosphate 3-kinase	F1MJE0 F1MYE0 F1MYM3 P23726 P23727 P32871	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2	Bos taurus (cattle)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	F1MGG8 F1MJE0 F1MYE0 G1K218 P07455 P07456	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Bos taurus (cattle)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	AMICA1 protein B-cell receptor CD22 Beta-2-microglobulin C-type lectin domain family 4 member G C5H12ORF53 protein CD19 molecule CD200 molecule CD200 molecule CD300 molecule like family member b CD300a molecule CD40 ligand CD40 ligand CD8 subunit beta CD81 antigen CD99 molecule CMRF35-like molecule 9 CRTAM protein Cell surface glycoprotein CD200 receptor 1 Collectin-12 Complement C3 Coxsackievirus and adenovirus receptor homolog Fc fragment of IgG receptor Ia Hematopoietic cell signal transducer Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin subtype domain-containing protein Immunoglobulin subtype domain-containing protein Integrin alpha-L Integrin beta-2 Integrin beta Integrin beta Integrin subunit alpha 4 Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein Interferon induced transmembrane protein 3 (1-8U) Interferon induced transmembrane protein 3 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 3 KLRF1 protein Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A Killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein Major histocompatibility class I related protein NKG2-D type II integral membrane protein NPDC1 protein Natural cytotoxicity triggering receptor 3 Natural killer cell cytotoxicity receptor 3 ligand 1 Nectin cell adhesion molecule 2 Osteoclast associated Ig-like receptor Paired immunoglobin like type 2 receptor alpha SLAM family member 6 SLAM family member 7 Sialic acid binding Ig like lectin 10 Sialic acid binding Ig like lectin 1 T-cell surface glycoprotein CD1b-1-like T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD8 alpha chain TRAV29-1*01 Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells like 1 Triggering receptor expressed on myeloid cells like 2 Tumor necrosis factor receptor superfamily member 5 UL16 binding protein 21 UL16-binding protein 17 ULBP13 Uncharacterized protein Uncharacterized protein Uncharacterized protein VCAM1 protein	A0A140T8D2 A0A3Q1LRW6 A0A3Q1LSQ1 A0A3Q1LT76 A0A3Q1M205 A0A3Q1M3D2 A0A3Q1M8C4 A0A3Q1MA43 A0A3Q1MAE8 A0A3Q1MD45 A0A3Q1ME80 A0A3Q1MKD6 A0A3Q1ML46 A0A3Q1MLJ0 A0A3Q1MNF5 A0A3Q1MQ30 A0A3Q1MRJ9 A0A3Q1MT21 A0A3Q1MT87 A0A3Q1MTX6 A0A3Q1NI55 A0A3Q1NLL2 A0A3Q1NN33 A0A3S5ZP99 A0A452DIT3 A4IFJ4 A5D7B2 A5D7V5 A5PJG8 A6H6Y6 A6QP79 A6QPH6 A6QQ36 A7MAZ7 A7MBB0 A7YW30 A7YWT5 E1B7F4 E1B8E5 E1B8Y2 E1BFU3 E1BGL8 E1BHM4 E1BI37 E1BI56 E1BLR0 F1MEF6 F1MG16 F1MGI2 F1MI38 F1MI53 F1MIE5 F1MJX3 F1MLN1 F1MNL2 F1MQD8 F1MQF0 F1MQX6 F1MRK8 F1MST2 F1MZE6 F1MZQ5 F1N4Y5 F1N586 F6RKH9 F7VJN2 G3MZR7 G3N2K2 G3X797 G3X7K3 G5E542 G5E587 G5E5B4 G5E5F5 G5E5G6 G5E5L3 G5E5L8 G5E5X5 G5E6I1 G8JL01 P01888 P32592 P61625 Q09YM2 Q09YM5 Q0VCU4 Q1XF11 Q28072 Q28073 Q28203 Q2UVX4 Q32LF2 Q3ZBV6 Q3ZC60 Q3ZCD0 Q8SPQ5 Q8WMV3	AMICA1 B2M BOLA BOLA-NC1 C3 C5H12ORF53 CAR CD18 CD19 CD1B5 CD200 CD200R CD200R1 CD22 CD247 CD300A CD300LB CD300LF CD300LG CD3D CD3E CD3G CD40 CD40LG CD81 CD8A CD8B CD99 CLEC4G CLM9 CLP1 COLEC12 CRTAM CXADR DAP10 FCGR1A HCST ICAM1 ICAM3 ICAM5 IFITM3 ITGA4 ITGAL ITGB1 ITGB2 ITGB7 JAML KIR2DL1 KIR2DL5A KIR2DS1 KIR3DL2 KIR3DS1 KLRF1 KLRK1 LOC100138951 LOC100850276 LOC100852061 LOC112443864 LOC112444847 LOC512286 LOC515418 LOC526163 LOC534578 LOC613699 LOC616254 LOC618268 LOC618463 LOC777594 LOC783508 MIC2 NCR3 NCR3LG1 NECTIN2 NPDC1 OSCAR PIANP PILRA SIGLEC1 SIGLEC10 SLAMF6 SLAMF7 TNFRSF5 TRAV29-1 TREM1 TREML1 TREML2 ULBP13 ULBP17 ULBP21 VCAM1	Bos taurus (cattle)
Inactivation of CSF3 (G-CSF) signaling	Colony stimulating factor 3 receptor Cullin-5 Elongin-C Granulocyte colony-stimulating factor Polyubiquitin-B Polyubiquitin-C Ring finger protein 7 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M5N0 A0A3Q1MHG9 A0A3Q1MXH0 A0A3Q1MYA3 E1B9W2 E1BCP6 F1MCX4 F1MSN0 F1N0D6 F1N261 P0CG53 P0CH28 P35833 P62992 P63048 Q0P5F4 Q1RMX2 Q2KII4 Q2TA10 Q3SZ32 Q9BEG9	CSF3 CSF3R CUL5 ELOC GCSF JAK1 JAK2 LYN RNF7 RPS27A SOCS1 SOCS3 SRC SYK TCEB1 TCEB2 TYK2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 UBE2D3	Bos taurus (cattle)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-like Calmodulin-lysine N-methyltransferase Cyclic nucleotide gated channel subunit beta 1 Cyclic nucleotide-gated channel alpha-1 EF-hand domain-containing protein G protein-coupled receptor kinase G protein-coupled receptor kinase Glycylpeptide N-tetradecanoyltransferase 2 Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein subunit beta-5 Guanylate cyclase Guanylate cyclase Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Methionine aminopeptidase 1 Methionine aminopeptidase 2 Phosphodiesterase Phosphodiesterase Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Recoverin Regulator of G-protein signaling 9-binding protein Regulator of G-protein signaling 9 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin kinase GRK1 Rhodopsin S-arrestin Serine/threonine-protein phosphatase with EF-hands	A0A3Q1MR28 A0A3S5ZPL0 A6QLA4 A7YWN4 E1B957 E1BK80 F1MBQ1 F1MH44 F1MLH6 F1MN48 F1MRI0 F1MTS7 F1MWV0 F1MY40 F1MYX4 F1MZK0 F1N081 F1N4Q2 P02698 P02699 P04695 P04972 P08168 P21457 P28327 P46065 P49355 Q00194 Q8MJG0 Q9N181	CALM CAMKMT CNCG CNCG1 CNGA1 CNGB1 FNTA FNTB GCAP1 GNAT1 GNB5 GNGT1 GRK1 GRK4 GRK7 GUCA1 GUCA1A GUCA1B GUCY2D GUCY2F LOC786620 METAP1 METAP2 NMT1 NMT2 PDE6A PDE6B PDE6G PDEG PPEF1 R9AP RCV1 RCVRN RGS9 RGS9BP RHO RHOK SAG	Bos taurus (cattle)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 12 G protein subunit beta 3 G protein subunit gamma 13 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 4 GNB4 protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Inward rectifier potassium channel 2 KCNJ10 protein KCNJ15 protein Potassium inwardly rectifying channel subfamily J member 16 Potassium inwardly rectifying channel subfamily J member 4	A0A3Q1M4V6 A0A3Q1NGS8 A0A3S5ZPL0 A2VDQ4 A4IFL6 A5PJL2 A5PKD6 E1B8Q3 E1BNE9 F1MF15 F1MIZ5 F1MUD1 F1MYR9 F1MYW8 O19182 P02698 P11017 P30671 P50154 P62871 P63212 P63214 P63217 Q0VD28 Q28024 Q3SZ98 Q4TZY1 Q5E9F0	GABBR1 GABBR2 GIRK1 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 IRK1 KCNJ10 KCNJ12 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6	Bos taurus (cattle)
Initial triggering of complement	Adiponectin B Collectin subfamily member 10 Collectin-11 Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1s Complement C2 Complement component 4A Ficolin-2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein MBL associated serine protease 1 MBL associated serine protease 2 Mannose-binding protein C Uncharacterized protein complement subcomponent C1r	A0A3B0IZF8 A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1M3L6 A0A3Q1M7Q5 A0A3Q1MGP1 A0A3Q1MLF4 E1BH06 E1BJ49 F1MVK1 F1MVS9 G3N0V0 O02659 Q17QH6 Q2KIV9 Q3SYW2 Q5E9E3 Q5I2E5	ADIB C1QA C1QB C1QC C1R C1S C2 C4A COLEC10 COLEC11 FCN2 LOC107131209 MASP1 MASP2 MBL	Bos taurus (cattle)	G49108TO G57321FI
Insulin receptor recycling	Cathepsin D Insulin-degrading enzyme Insulin Receptor-type tyrosine-protein phosphatase F Tyrosine-protein kinase receptor Tyrosine-protein phosphatase non-receptor type V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit	A0A3Q1MS24 A0A452DI38 A0A452DJ67 A4IFJ9 A5PJB2 A6QQN2 A7MBJ4 E1BGJ7 E1BMV6 F1MMR6 F1MV64 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P40682 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q24K02 Q28029 Q2KJB6 Q2TA24 Q32LB7	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6IP1 ATP6N1B ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CTSD IDE INS INSR LOC101904667 PTPN1 PTPRF TCIRG1 VATC VATF VPATPD	Bos taurus (cattle)
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A3Q1LNN8 A5PJB2 F1MV64 F1N7C3 Q0IIE2 Q3T0F9	GRB10 GRB2 INS INSR SHC1 SOS1	Bos taurus (cattle)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen type IV alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVIII alpha 1 chain Fibrillin-1 Fibronectin Integrin alpha-3 Integrin alpha-L Integrin beta-2 Integrin beta-6 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 4 Integrin subunit alpha 6 Integrin subunit alpha 9 Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein JAM2 protein Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Platelet and endothelial cell adhesion molecule 1 Purinergic receptor P2X 5 Secreted phosphoprotein 1 Tenascin C Thrombospondin 1 VCAM1 protein VWFA domain-containing protein Vitronectin	A0A140T8D2 A0A3Q1LT76 A0A3Q1LZT3 A0A3Q1LZU0 A0A3Q1M8K4 A0A3Q1MFX6 A0A3Q1MHJ9 A0A3Q1MQV3 A0A3Q1MSS6 A0A3Q1MXS2 A4IFI9 A7MBB0 E1BDD5 E1BFX5 E1BLR0 F1MBA3 F1MEF6 F1MGZ4 F1MI38 F1MMH2 F1MMN6 F1MMS9 F1MQF0 F1MQT9 F1MRZ6 F1MTN1 F1MVW3 F1MZU6 F1N157 F1N6W9 F6RFP6 F6RKH9 F6RND5 G3MXK9 G3MYD9 G5E5A9 P32592 P35445 P61625 P98133 Q05443 Q28862 Q3ZBS7 Q7SIB2 Q8SQB8 Q8SQB9 Q9XT56	BSG CD18 CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A3 COMP F11R FBN1 FN1 IBSP ICAM1 ICAM3 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA6 ITGA9 ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM1 JAM2 LDC LOC534578 LOC616254 LUM P2RX5 PECAM1 SPP1 THBS1 TNC VCAM1 VTN	Bos taurus (cattle)
Interaction With Cumulus Cells And The Zona Pellucida	Beta-1,4-galactosyltransferase 1 Disintegrin and metalloproteinase domain-containing protein 2 Hyaluronidase Oviduct-specific glycoprotein Zona pellucida sperm-binding protein 2 Zona pellucida sperm-binding protein 3 Zona pellucida sperm-binding protein 4	A0A3Q1MHW1 A0A3S5ZPD7 A6H6X7 F1MZM9 G1K1H0 P08037 Q9BH11	ADAM2 B4GALT1 GALT GGTB2 LOC509761 OVGP1 ZP2 ZP3 ZP4 ZPB	Bos taurus (cattle)

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