GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **557** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Phase I - Functionalization of compounds	Aldehyde dehydrogenase Alpha/beta hydrolase fold-3 domain-containing protein Amine oxidase [copper-containing] 3 Amine oxidase Amine oxidase Amine oxidase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like CYB5B protein Carbonyl reductase (NADPH) Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily B member 6 Epoxide hydrolase Mitochondrial amidoxime reducing component 1 Mitochondrial amidoxime reducing component 2 NAD(P)H dehydrogenase, quinone 2 NADH-cytochrome b5 reductase 3 Primary amine oxidase, liver isozyme	A0A3Q1LGS8 A0A3Q1LKX3 A0A3Q1LZ03 A0A3Q1M7J3 A0A3Q1MQJ1 A0A3Q1MU42 A0A452DHX8 E1BC09 F1MFG7 F1MI11 F1ML85 F1MU22 F1MYL2 F1N015 G3X6I4 G3X6X4 G5E6I5 P07514 Q0P5F6 Q0VC97 Q1LZH1 Q29437 Q29RV2 Q3MHQ1 Q3SZT2 Q3T047 Q3ZCJ6 Q9TTK6	AADAC ABP1 AHR ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5R3 CYP2B6 CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 DIA1 EPHX1 LOC100138645 MARC2 MOSC2 MTARC1 MTARC2 NQO2	Bos taurus (cattle)
Glutathione conjugation	Aldo-keto reductase family 1 member A1 Glutathione S-transferase 3, mitochondrial Glutathione S-transferase A2 Glutathione S-transferase A4 Glutathione S-transferase kappa Glutathione S-transferase omega Glutathione S-transferase theta-1 Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione-dependent dehydroascorbate reductase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 S-formylglutathione hydrolase glutathione transferase glutathione transferase	A0A3Q1LMV5 A0A3Q1LSN6 A0A3Q1LY34 A0A3Q1MEC8 A0A452DHY4 A1A4L7 E1BED9 E1BJ08 E1BKD8 F1MGZ9 F1MRG0 F1MUX5 F1MX44 F1MXY2 O18879 Q08E20 Q2KJG4 Q2NL00 Q3T100 Q3ZCJ2 Q5E9G0	AKR1A1 ESD GSTA1 GSTA2 GSTA4 GSTA5 GSTK1 GSTM1 GSTM3 GSTM4 GSTO2 GSTP1 GSTT1 HPGDS LOC100295687 MGST1 MGST2 MGST3	Bos taurus (cattle)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	A0A493UA87 Q58D31	AKR1B1 SORD	Bos taurus (cattle)	G58161NS
Aflatoxin activation and detoxification	Aldo-keto reductase family 7 member A2 Aldo-keto reductase family 7 member A2 Cytochrome P450 1A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 Dipeptidase 1 Dipeptidase 3 Dipeptidase Glutathione S-transferase 3, mitochondrial Glutathione hydrolase 7 Glutathione hydrolase Glutathione hydrolase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 N-acyl-aliphatic-L-amino acid amidohydrolase	A0A3Q1LZ03 E1BDI1 E1BIR2 F1MHN9 F1MR63 F1MXY2 F1MYJ3 F1MZC0 F1N6I4 G3MYH2 G3N2D8 G3X6I4 Q0V8L2 Q29RV2 Q2KJG4 Q3SZM7 Q3T047 Q3T100	ACY1 AKR7A2 CYP1A2 CYP2A13 CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 DPEP1 DPEP2 DPEP3 GGT1 GGT5 GGT7 GGTL3 MGST1 MGST2 MGST3	Bos taurus (cattle)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Alpha isoform of regulatory subunit A, protein phosphatase 2 Amphiregulin Betacellulin CD19 molecule CD80 molecule CD86 molecule Epiregulin Epithelial mitogen Estrogen receptor beta Estrogen receptor FLT3LG protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Immediate early response 3 Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 PIP5K1A protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphatidylinositol-4-phosphate 5-kinase type 1 beta Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Phosphatidylinositol-5-phosphate 4-kinase type 2 beta Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein phosphatase 2 scaffold subunit Abeta Proto-oncogene vav Ras homolog family member G Ras-related C3 botulinum toxin substrate 2 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LRU7 A0A3Q1LUE0 A0A3Q1M3Q3 A0A3Q1M535 A0A3Q1M7J4 A0A3Q1M864 A0A3Q1MBL1 A0A3Q1MCW9 A0A3Q1ME99 A0A3Q1MGW7 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MLL9 A0A3Q1MPT9 A0A3Q1N3Z8 A0A3Q1NAV6 A0A3Q1ND77 A0A3S5ZP81 A0A452DHW6 A0A452DHX3 A0JNB0 A0MTF4 A2VDZ0 A2VE24 A2VE27 A4FV68 A5D973 A5PJB2 A6QLC5 A6QLU3 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1B8P9 E1BAI2 E1BBE2 E1BDM2 E1BE66 E1BFL8 E1BFP8 E1BGY3 E1BHC1 E1BIM8 E1BIN8 E1BJU2 E1BP37 F1MCQ7 F1MDQ5 F1MEV4 F1MHC6 F1MHR4 F1MHT2 F1MJE0 F1MN51 F1MPD0 F1MQN0 F1MRU0 F1MRU1 F1MS28 F1MV64 F1MYE0 F1MYM3 F1MZD6 F1N1S8 F1N339 F1N4S9 F1N586 F1N6G8 F1N7M1 F2Z4J0 G3MXR4 G3N104 G3XGD3 P03968 P03969 P23726 P23727 P32871 P46196 P49884 P67774 Q08DN7 Q08DP7 Q08DU3 Q0P594 Q0P5F7 Q0P5G7 Q1RMI2 Q1RMT8 Q28132 Q2KJ15 Q2LGB3 Q3T0F9 Q3ZCC3 Q3ZCM0 Q58DF9 Q9TU25 Q9XSB5 Z4YHD9	AFGF AREG BTC CD19 CD28 CD80 CD86 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ERK2 ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HBGF-1 HGF ICOS IER3 IL1RL1 IL33 INS INSR IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MAPK1 MAPK3 MET MYD88 NR3A1 NR3A2 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5K2C PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5D PPP2R5E PRKM1 PTPN11 RAC2 RHOG SCF SRC STRN TGFA TRAF6 TRAT1 VAV1	Bos taurus (cattle)
CTLA4 inhibitory signaling	Alpha isoform of regulatory subunit A, protein phosphatase 2 CD80 molecule CD86 molecule Cytotoxic T-lymphocyte protein 4 Protein phosphatase 2 scaffold subunit Abeta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A3Q1MLL9 A0A3S5ZP81 A0JNB0 A2VDZ0 A4FV68 A5D973 A7MB57 E1BIM8 F1MQN0 F1N1S8 F1N261 F1N339 P67774 Q08DP7 Q0P594 Q28090 Q3ZCM0	CD152 CD80 CD86 CTLA-4 CTLA4 FYN LCK LYN PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5D PPP2R5E PTPN11 SRC YES1	Bos taurus (cattle)
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase 7 Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Beta-1,4-N-acetyl-galactosaminyltransferase 2 Fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase L-Fucosyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A3Q1LUC6 A0A3Q1MGH3 A0A452DJH9 E1BIT9 F1MBS8 F1MDG4 F1MUS1 F1MWE7 F1N557 F1N751 G3MZR2 Q2HJA3 Q3T0R9 Q6H8M7	B3GALT2 B3GALT4 B4GALNT2 FUT10 FUT11 FUT2 FUT4 FUT6 FUT7 FUT9 SIAT10 ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Bos taurus (cattle)	G39211DH G81971FM G83633HB G90387AM G98173LG
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase Alpha-mannosidase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Fucosyltransferase Glycoprotein hormones alpha chain Lutropin subunit beta Tissue alpha-L-fucosidase	A0A3Q1M1B8 C0LMH8 E1BB36 E1BGJ4 F1MBS8 F1N4H9 F1N7T2 P01217 P04651 Q2KIM0	CGA CHST10 CHST8 FUCA1 FUT6 FUT8 LHB MAN2A1 MAN2A2 MGAT2	Bos taurus (cattle)	G70323CJ G82576YO
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	F1ML11 Q5E9I4	MANEA MGAT1	Bos taurus (cattle)	G58161NS
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Beta-1,4-galactosyltransferase 1 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase MGAT4 family member C MGAT4B protein ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase	A0A3Q1LM08 A0A3Q1LV92 A0A3Q1LZS9 A0A3Q1MGH3 A6QQ63 E1BCQ2 E1BNB2 F1MUJ7 F6RH18 F6RJ53 O77836 P08037	B4GALT1 B4GALT2 B4GALT4 B4GALT5 B4GALT6 GALT GGTB2 MGAT4A MGAT4B MGAT4C MGAT5 ST3GAL4 ST8SIA2 ST8SIA3	Bos taurus (cattle)	G81533KY
Glycogen breakdown (glycogenolysis)	Alpha-1,4 glucan phosphorylase Calmodulin-like EF-hand domain-containing protein Glycogen debranching enzyme Glycogen phosphorylase, liver form Lysosomal alpha-glucosidase Phosphorylase b kinase gamma catalytic chain, liver/testis isoform Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit glycogenin glucosyltransferase glycogenin glucosyltransferase	A0A3Q1LZJ1 A0A3Q1MR28 A0A3Q1N3K8 A0A3Q1NLJ5 F1MHT1 F1MJ28 F1MLH6 G3X778 Q0VCM4 Q2KJ16 Q9MYM4	AGL CALM GAA GYG1 GYG2 PHKA1 PHKA2 PHKG2 PYGL PYGM	Bos taurus (cattle)	G58161NS
COPII-mediated vesicle transport	Alpha-1-antiproteinase Amphiregulin Ankyrin repeat domain 28 Bet1 golgi vesicular membrane trafficking protein Beta-soluble NSF attachment protein CD59 glycoprotein Casein kinase I isoform delta Cathepsin Z Coagulation factor V Coagulation factor VIII Dipeptidyl peptidase 1 Folate receptor 3 Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor Golgi SNAP receptor complex member 2 Golgi reassembly stacking protein 1 Golgin A2 LMAN2 protein Lectin, mannose binding 1 like Lectin, mannose binding 1 Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit NSF attachment protein alpha Prolactin regulatory element-binding protein Protein SEC13 homolog Protein cornichon homolog 1 Protein cornichon homolog 2 Protein phosphatase 6 regulatory subunit 1 Protein phosphatase 6 regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec24A Protein transport protein Sec31A Protein transport protein sec16 Protein transport protein sec16 Ras-related protein Rab-1A SEC22A protein SEC23 interacting protein SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Sec1 family domain containing 1 Serine/threonine-protein phosphatase Small COPII coat GTPase SAR1B Synaptobrevin homolog YKT6 Syntaxin-17 Syntaxin-5 TBC1 domain family member 20 TFG protein Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Transforming growth factor alpha Transmembrane emp24 domain-containing protein 10 VIP36-like protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b Vesicle-trafficking protein SEC22c small monomeric GTPase	A0A3Q1LSE5 A0A3Q1LTM9 A0A3Q1LUP7 A0A3Q1M072 A0A3Q1M4U3 A0A3Q1M5V0 A0A3Q1M762 A0A3Q1M7J4 A0A3Q1M7M6 A0A3Q1MFL2 A0A3Q1MJE3 A0A3Q1MMA1 A0A3Q1MRB3 A0A3Q1MSA1 A0A3Q1MWA3 A0A3Q1N147 A0A3Q1NDZ1 A4FUG1 A6H7F7 A6QNT8 A6QP36 A7Z051 E1BG76 E1BIU0 E1BJ99 E1BKW5 E1BL12 E1BMP2 E1BN43 E1BPR4 F1MEV4 F1MSD6 F1MTG7 F1MV07 F1MVW5 F1N0I3 F1N455 F1N6K7 F6Q334 G0T3G6 G3N214 G5E5W1 P05689 P34955 P35508 P41541 P81126 Q08DB5 Q17QI1 Q2HJD1 Q2KIC7 Q2T9Q1 Q2TBL9 Q2YDJ2 Q32L78 Q32PA1 Q3SX36 Q3T000 Q3T086 Q3T0F2 Q3T0T7 Q3ZCC9 Q5BIN6 Q5E971 Q5E9Y2	ANKRD28 AREG BET1 CD59 CNIH CNIH1 CSNK1D CTSC CTSZ F5 F8 FOLR3 GOLGA2 GORASP1 GOSR2 GRIA1 HCKID LMAN1 LMAN1L LMAN2 LMAN2L MCFD2 NAPA NAPB NAPG NSF PI PPP6C PPP6R1 PPP6R3 PREB RAB1A RAB1B SAPS3 SAR1B SCFD1 SEC13 SEC13L1 SEC16A SEC16B SEC22A SEC22B SEC22C SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SERPINA1 SNAPB STX17 STX5 TBC1D20 TFG TGFA TMED10 TMP21 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 USO1 VDP VIPL YKT6	Bos taurus (cattle)
Cargo concentration in the ER	Alpha-1-antiproteinase Amphiregulin CD59 glycoprotein Cathepsin Z Coagulation factor V Coagulation factor VIII Dipeptidyl peptidase 1 Folate receptor 3 Glutamate receptor Golgi SNAP receptor complex member 2 LMAN2 protein Lectin, mannose binding 1 like Lectin, mannose binding 1 Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit Prolactin regulatory element-binding protein Protein cornichon homolog 1 Protein cornichon homolog 2 Protein transport protein SEC23 Protein transport protein Sec24A SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component SH3 domain-containing protein Small COPII coat GTPase SAR1B Syntaxin-5 Transforming growth factor alpha Transmembrane emp24 domain-containing protein 10 VIP36-like protein Vesicle-trafficking protein SEC22b	A0A3Q1LM15 A0A3Q1LUP7 A0A3Q1M762 A0A3Q1M7J4 A0A3Q1MFL2 A0A3Q1MMA1 A0A3Q1MSA1 A0A3Q1NDZ1 A6QNT8 A6QP36 E1BIU0 E1BJ99 E1BL12 E1BPR4 F1MEV4 F1MV07 F1MVW5 F1N0I3 F1N455 G0T3G6 G5E5W1 P05689 P34955 Q08DB5 Q2HJD1 Q32PA1 Q3T0T7 Q5BIN6 Q5E971	AREG CD59 CNIH CNIH1 CTSC CTSZ F5 F8 FOLR3 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L MCFD2 MIA2 PI PREB RAB1B SAR1B SEC22B SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 TGFA TMED10 TMP21 VIPL	Bos taurus (cattle)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	A0A3Q1LQ48 A0A3Q1MAT2 A0A3Q1MQZ8 E1B7W0 F1MGA6 F6R653 G3X6S2 Q28044 Q28838	ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3	Bos taurus (cattle)
Dissolution of Fibrin Clot	Alpha-2-antiplasmin Annexin A2 Histidine-rich glycoprotein Plasminogen activator inhibitor 1 Plasminogen activator Plasminogen Protein S100-A10 Serine protease inhibitor clade E member 2 Serpin B6 Serpin B8 Uncharacterized protein Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator	A0A452DIF6 A0A452DIJ9 E1B726 F1MG91 F1MKS5 F1N0T3 P04272 P28800 P60902 Q05588 Q05589 Q5BIR5 Q8HZY1	ANX2 ANXA2 CAL1L CLP11 HRG LOC281376 LOC617406 PLAT PLAU PLAUR PLG PLI S100A10 SERPINB8 SERPINE1 SERPINE2 SERPINF2	Bos taurus (cattle)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	A0A3Q1LQ48 G3X6S2 Q28838	ADRA2A ADRA2B ADRA2C	Bos taurus (cattle)
Sialic acid metabolism	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase Carboxypeptidase Gal-NAc6S Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acetylneuraminic acid phosphatase N-acylneuraminate cytidylyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Sialidase-1 Solute carrier family 17 member 5 Solute carrier family 35 (CMP-sialic acid transporter), member A1 Type 2 lactosamine alpha-2,3-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase	A0A3Q1LM08 A0A3Q1LRX1 A0A3Q1LUC6 A0A3Q1LZS9 A0A3Q1MGH3 A0A3Q1N8K2 A0A3Q1NDQ7 A0A452DJ87 A0A452DJH9 A5D7T4 A5D960 A6BMK7 A7YWM8 E1B7R3 E1BMN0 F1MIL9 F1MRJ3 F1MVI9 F1MXN8 F1N2J4 F1N6V7 F1N7G6 G3N3B2 G5E5Q1 Q1RMX7 Q29RY9 Q3SZM5 Q3SZP1 Q6H8M7 Q6H8M9	CMAS CTSA GLB1 GNE NANP NANS NEU1 NEU2 NEU3 NEU4 NPL SIAT10 SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 siat4B	Bos taurus (cattle)
Striated Muscle Contraction	Alpha-actinin-2 Alpha-actinin-3 Desmin Dystrophin MYBPC1 protein MYH3 protein Myosin heavy chain 8 Myosin light chain 1/3, skeletal muscle isoform Myosin regulatory light chain 2, ventricular/cardiac muscle isoform Myosin, light chain 4, alkali; atrial, embryonic Myosin-6 Myosin-binding protein C, cardiac-type Nebulin Telethonin Tropomodulin 2 Tropomodulin 3 Tropomodulin-1 Tropomodulin-4 Tropomyosin alpha-1 chain Tropomyosin alpha-3 chain Tropomyosin beta chain Troponin C, skeletal muscle Troponin C, slow skeletal and cardiac muscles Troponin I, fast skeletal muscle Troponin I1, slow skeletal type Troponin T, cardiac muscle Troponin T, fast skeletal muscle Troponin T, slow skeletal muscle Vimentin	A0A3Q1LL62 A0A3Q1LVZ9 A0A3Q1M1N1 A0A3Q1M4Y0 A0A3Q1MC60 A0A3Q1N6P5 A0A452DJI6 A0JNC0 A0JNJ5 A6QP89 A6QPA6 E1BAI7 F1N2G0 F6QIC1 G3MYN5 G3MZK7 G3N264 O62654 P48616 P63315 Q0III9 Q0VC48 Q1RMM7 Q3ZC55 Q5KR47 Q5KR48 Q5KR49 Q6T8D8 Q8MKH6	ACTN2 ACTN3 DES DMD MYBPC1 MYBPC3 MYH3 MYH6 MYH8 MYL1 MYL2 MYL4 NEB TCAP TMOD1 TMOD2 TMOD3 TMOD4 TNNC TNNC1 TNNC2 TNNI1 TNNI2 TNNT1 TNNT2 TNNT3 TPM1 TPM2 TPM3 VIM	Bos taurus (cattle)
RAF/MAP kinase cascade	Alpha-actinin-2 Amphiregulin Angiopoietin-1 receptor Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Betacellulin Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 EF-hand domain-containing protein Epiregulin Epithelial mitogen FLT3LG protein FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Focal adhesion kinase 1 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GTPase NRas Glial cell derived neurotrophic factor Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Kit ligand Klotho beta Klotho Linker for activation of T cells Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Neuregulin 2 Neuregulin 3 Neurofilament light polypeptide Neurturin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret RAS guanyl releasing protein 3 RAS guanyl releasing protein 4 RAS guanyl-releasing protein 1 Ral guanine nucleotide dissociation stimulator like 1 Ral guanine nucleotide dissociation stimulator like 3 Ral guanine nucleotide dissociation stimulator-like 2 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras protein specific guanine nucleotide releasing factor 1 Ras protein specific guanine nucleotide releasing factor 2 RasGEF domain family member 1A Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor-type tyrosine-protein phosphatase alpha SHC adaptor protein 2 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta, non-erythrocytic 4 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A3Q1LI10 A0A3Q1LK34 A0A3Q1LNC8 A0A3Q1LRU7 A0A3Q1LSU3 A0A3Q1LUE0 A0A3Q1M0Y1 A0A3Q1M3Q3 A0A3Q1M6Z6 A0A3Q1M7J4 A0A3Q1MBH0 A0A3Q1MD11 A0A3Q1ME99 A0A3Q1MFJ1 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MKC7 A0A3Q1MPB6 A0A3Q1MPT9 A0A3Q1MR28 A0A3Q1N010 A0A3Q1N3Z8 A0A3Q1N508 A0A3Q1N8H3 A0A3Q1NAC7 A0A3Q1NAV6 A0A452DHX3 A0A452DJB1 A0JNB0 A0MTF4 A2VE24 A2VE27 A2VE30 A4IFA9 A5D7R9 A6H792 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1B8P9 E1BAI2 E1BBE2 E1BCP6 E1BD76 E1BDM2 E1BEL4 E1BFP8 E1BG59 E1BGY3 E1BHC1 E1BIN8 E1BJC7 E1BJU2 E1BKU1 E1BLT3 E1BM01 E1BMN5 E1BMX0 E1BP37 F1MCQ7 F1MEV4 F1MH16 F1MHC6 F1MJE0 F1MKE9 F1MLH6 F1MM66 F1MMQ8 F1MN51 F1MP52 F1MPD0 F1MRU0 F1MS00 F1MS28 F1MSG6 F1MXH7 F1MYE0 F1MYM3 F1MZ60 F1MZD6 F1N0D6 F1N4S9 F1N5N3 F1N6G8 F1N7C3 F2Z4J0 F6S0Q2 G3MXR4 G3MZM3 G3N104 G3XGD3 O18920 P02548 P03968 P03969 P05016 P11052 P23726 P23727 P32871 P46196 P49875 P52173 Q06807 Q0IIE2 Q0VCY4 Q0VCY8 Q28132 Q2HJF7 Q2KJ15 Q3MHJ9 Q3T0F9 Q3ZC55 Q95118 Z4YHD9	ACTN2 AFGF ANG1 ANGPT1 AREG ARTN BTC CALM CAMK2A CAMK2B CAMK2D CSF2 CSF2RB DLG1 DLG3 DLG4 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ERK2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FRS3 FYN Fgf4 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 HBEGF HBGF-1 HGF IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA IRS1 IRS2 JAK1 JAK2 JAK3 KIT KITLG KL KLB KRAS LAT MAPK1 MAPK3 MET NEFL NRAPGEP NRAS NRG1 NRG2 NRG3 NRTN ODAD3 PDGFA PDGFB PDGFRA PDGFRB PDZGEF1 PEA15 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PTK2 PTPRA RALGDS RANBP9 RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP1 RASGRP3 RASGRP4 RET RGL1 RGL2 RGL3 SCF SHC1 SHC2 SHC3 SOS1 SPTA1 SPTAN1 SPTB SPTBN2 SPTBN4 TEK TGFA TIE-2 TIE2	Bos taurus (cattle)
Digestion of dietary carbohydrate	Alpha-amylase Lactase Maltase-glucoamylase 2 (putative) Sucrase-isomaltase chitinase	E1BGH5 E1BK89 F1MH27 F1MP21 G3N3S2	CHIA LCT LOC539383 MGAM2 SI	Bos taurus (cattle)	G58161NS G74621DY G93924TT G96370VA
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Beta-mannosidase Lysosomal alpha-mannosidase alpha-mannosidase	A0A3Q1MEZ5 A0A3S5ZPJ9 F1MWT0 Q29451	LOC528518 MAN2B1 MAN2C1 MANB MANBA	Bos taurus (cattle)	G00027MO G25577BM G28233ME G70323CJ G90333CG
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1 Histone deacetylase 6	F1MQP3 Q58CX6	ATAT1 HDAC6 MEC17	Bos taurus (cattle)
Sensory perception of salty taste	Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Sodium channel epithelial 1 subunit delta	A5D7U4 F1MJW3 F1MY57 P55270	SCNN1A SCNN1B SCNN1D SCNN1G	Bos taurus (cattle)
Norepinephrine Neurotransmitter Release Cycle	Amine oxidase [flavin-containing] A Complexin-1 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Solute carrier family 18 (Vesicular monoamine), member 2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2	A0A3Q1LQ22 A0A3Q1LZT1 A0A3Q1M5L6 A0A3Q1MBH3 A7MBE0 B0JYP2 E1BHW6 E1BIA1 F1N7B7 P11023 P21398 P32850 P48018 P61763 P63026 Q0IIL7 Q17QQ3	CPLX1 MAOA OCT1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RIMS1 SLC18A2 SLC22A1 SLC22A2 SNAP25 STX1A STXBP1 SYB2 SYT1 UNC13B UNC18A VAMP2	Bos taurus (cattle)
Glutamate Neurotransmitter Release Cycle	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Complexin-1 Excitatory amino acid transporter 1 PRA1 family protein 3 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Sodium-coupled neutral amino acid symporter 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2 Vesicular glutamate transporter 1 glutaminase glutaminase	A0A3Q1LQ22 A0A3Q1LZT1 A0A3Q1M5L6 A0A3Q1MBH3 A0A3Q1MR13 A2VE31 A4FV52 A6H774 E1BHZ6 E1BIA1 F1MJN4 F1MM79 F1MUT8 F1N7B7 P11023 P32850 P46411 P48018 P61763 P63026 Q0IIL7 Q17QQ3 Q5E9M1	ARL6IP5 CPLX1 EAAT1 GLAST GLAST1 GLS GLS2 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PRAF3 RAB3A RIMS1 SLC17A7 SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC38A2 SNAP25 SNAT2 STX1A STXBP1 SYB2 SYT1 UNC13B UNC18A VAMP2 VGLUT1	Bos taurus (cattle)

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