GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
PCP/CE pathway	Dishevelled associated activator of morphosis 1 Dishevelled segment polarity protein 1 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Frizzled class receptor 3 Frizzled class receptor 7 Frizzled-1 Frizzled-6 Profilin-1 Protein Wnt Protein Wnt Protein Wnt Protein Wnt RAC3 protein Ras-related C3 botulinum toxin substrate 2 Transforming protein RhoA	A0A3Q1LHF1 A0A3Q1MDX6 A0A3Q1MJR6 A0A3Q1MSZ4 A5PK69 A7MB15 E1BDG5 E1BEN9 F1MMW6 F1MP23 F1N4C0 F1N4K7 F1N6M9 P02584 P61585 Q9TU25	ARHA DAAM1 DVL1 DVL2 DVL3 FZD1 FZD3 FZD6 FZD7 PFN1 RAC2 RAC3 RHO12 RHOA WNT1 WNT11 WNT4 WNT5A	Bos taurus (cattle)
Signaling by PDGF	Collagen alpha-1(IV) chain Collagen type VI alpha 1 chain Collagen type VI alpha 2 chain Collagen type VI alpha 3 chain Collagen type VI alpha 5 chain Collagen type VI alpha 6 chain Plasminogen activator Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Secreted phosphoprotein 1 Thrombospondin 1 Thrombospondin 2 Thrombospondin 3 Thrombospondin 4 furin protein-tyrosine-phosphatase	A0A3Q1LXW3 A0A3Q1LZU0 A0A3Q1M0B4 A0A3Q1ME99 A0A3Q1MQV3 A0A3Q1MQX0 A0A3Q1N3Z8 A0A452DIF6 A0A452DJ62 A4IFC0 B0JYR0 B1H0W5 E1B726 E1BB91 E1BI98 E1BJY4 F1MD40 F1MKG2 F1N1W3 Q2KJ15 Q7SIB2	COL4A1 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 FURIN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PLAT PLG PTPN12 SPP1 THBS1 THBS2 THBS3 THBS4	Bos taurus (cattle)
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin, cytoplasmic 2 Albumin Alpha-1-acid glycoprotein Alpha-1-antiproteinase Alpha-1B-glycoprotein Alpha-2-HS-glycoprotein Alpha-2-antiplasmin Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-4 Amyloid-beta A4 protein Annexin Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 C-X-C motif chemokine C-type lectin domain family 3 member B CD63 antigen CD9 antigen CYFIP-related Rac1 interactor B Calmodulin-like Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor VIII Coagulation factor XIII A chain Complement factor D EF-hand domain-containing protein ENDOD1 protein FIGF protein Fermitin family homolog 3 Fibronectin Filamin A Fructose-bisphosphate aldolase GTP binding protein 2 Galectin-3-binding protein Growth arrest specific 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Hyaluronan binding protein 4 Immunoglobulin superfamily containing leucine-rich repeat protein Insulin-like growth factor I Insulin-like growth factor II Integrin beta Integrin subunit alpha 2b Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen 1 LHFPL tetraspan subfamily member 2 Left-right determination factor Left-right determination factor Lymphocyte antigen 6 complex locus G6F Lysosomal associated membrane protein 2 MAGE family member D2 MICOS complex subunit MIC27 Mesencephalic astrocyte-derived neurotrophic factor Multimerin 1 NADH-cytochrome b5 reductase 1 NHL repeat-containing protein 2 NTR domain-containing protein Obg-like ATPase 1 Phosphatase and actin regulator Plasminogen activator inhibitor 1 Plasminogen Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Prosaposin Protein FAM3C Proteoglycan 1-like Protocadherin 7 Ras-related protein Rab-27B Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selenoprotein P Serotransferrin Serpin family G member 1 Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Synaptotagmin like 4 Syntaxin-binding protein 2 Talin 1 Thrombospondin 1 Thymosin beta Torsin family 4 member A Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta Transgelin-2 Tubulin alpha-4A chain Vascular endothelial growth factor A Vascular endothelial growth factor B Vascular endothelial growth factor C Vinculin Vitamin K-dependent protein S WD repeat domain 1 p-selectin protein disulfide-isomerase von Willebrand factor	A0A140T843 A0A140T897 A0A140T8C6 A0A140T8C8 A0A1L6ZA12 A0A3Q1LMG1 A0A3Q1LN74 A0A3Q1LTE4 A0A3Q1LUG2 A0A3Q1M2H1 A0A3Q1MHJ9 A0A3Q1MLQ7 A0A3Q1MQV3 A0A3Q1MR28 A0A3Q1N449 A0A3Q1N8P4 A0A452DIJ9 A0A452DIU4 A0A452DIX0 A4FV53 A4IF69 A4IFA6 A5D7D1 A5PK28 A5PKI3 A6H754 A6QL97 A6QLI2 A6QP91 A6QPF9 A7E3W2 A7MBB6 A7YY77 B1H0W5 E1B726 E1B8Z0 E1BBY0 E1BCK4 E1BH14 E1BMJ0 F1MD83 F1MGZ4 F1MHC2 F1MK25 F1MKS5 F1MLH6 F1MNQ4 F1MRZ8 F1MTN1 F1MTP5 F1MUC1 F1MW44 F1MX05 F1MY12 F1MZ40 F1MZD6 F1N0I3 F1N0R5 F1N169 F1N789 F6QVC9 F6RT22 G3X6N3 G3X7J5 G5E5A9 G5E5W1 G8JKY5 P00442 P07224 P07455 P07456 P12763 P13213 P15497 P15691 P17697 P21214 P26201 P28800 P30932 P34955 P49907 P56652 P63258 P80513 P81948 Q17QL4 Q27967 Q29RS5 Q2HJ33 Q2KJ15 Q2KJF1 Q2KJI3 Q32LP0 Q3B7N2 Q3MHW9 Q3SZ27 Q3T0A3 Q3ZC55 Q56K11 Q5E9F5 Q5EAB4 Q5GN72 Q8HZJ5 Q9XS49 Q9XS50 Q9XSK2	A1BG ACTG ACTG1 ACTN1 ACTN2 ACTN4 AGP AHSG ALB ALDOA ANXA5 APOA1 APOH APOL APP ARMET ARP BRPF3 CALM CD36 CD63 CD9 CDC37L1 CFD CHID1 CLEC3B CLU CTSW CYB5R1 CYRIB ENDOD1 F13A1 F5 F8 FAM121A FAM3C FAM49B FERMT3 FETUA FIGF FLNA FN1 GAS6 GTPBP2 HABP4 HGF HRG IGF1 IGF2 ILEI ISLR ITGA2B ITGB3 ITIH3 KIND3 KNG1 LAMP2 LEFTY2 LGALS3BP LHFPL2 LOC112442231 LOC515333 MAGED2 MANF MIC27 MMRN1 NHLRC2 OLA1 ORM1 PAS4 PCDH7 PCYOX1L PDGFA PDGFB PECAM1 PHACTR2 PI PLEK PLG PLI PPBP PROS PROS1 PSAP RAB27B RARRES2 SCCPDH SCG3 SELENOP SELP SERPINA1 SERPINE1 SERPINF2 SERPING1 SOD1 SPARC SPP2 SPP24 SRGN STXBP2 SYTL4 TAGLN2 TF TGFB1 TGFB2 TGFB3 THBS1 TLN1 TMSB4X TMX3 TOR4A TUBA1 TUBA4A URP2 VCL VEGF VEGFA VEGFB VEGFC VEGFD VRF VWF WDR1 agp ly6g6f	Bos taurus (cattle)
Regulation of Complement cascade	Adiponectin B C3a anaphylatoxin chemotactic receptor C5L2 C5a anaphylatoxin chemotactic receptor 1 CD19 molecule CD55 molecule (Cromer blood group) CD59 glycoprotein CD81 antigen CPN2 protein Carboxypeptidase B2 Carboxypeptidase N subunit 1 Clusterin Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1s Complement C2 Complement C3 Complement C5 Complement C7 Complement C8 alpha chain Complement component 4A Complement component C8 beta chain Complement component C9 Complement factor B Complement factor H related 5 Complement factor H Complement factor I Elastase, neutrophil expressed Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Prothrombin Serpin family G member 1 Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A3B0IZF8 A0A3Q1LI40 A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1LQX2 A0A3Q1LSC6 A0A3Q1M3I2 A0A3Q1M3L6 A0A3Q1M7Q5 A0A3Q1MF14 A0A3Q1MGP1 A0A3Q1MP45 A0A452DI66 A4IFF5 A6QP30 E1BH06 E1BMJ0 F1MC45 F1MLR1 F1MVK1 F1MX87 F1MY85 F1N102 F1N586 G3MWP1 G3N0V0 G5E5V0 P17697 P81187 Q08DZ7 Q2KIG3 Q2KIV9 Q2UVX4 Q32PA1 Q3MHN2 Q3SYW2 Q3ZBS7 Q3ZCD0 Q5E9E3 Q673L2	ADIB BF C1QA C1QB C1QC C1R C1S C2 C3 C3AR1 C4A C5 C5AR1 C5AR2 C5L2 C7 C8A C8B C9 CD19 CD55 CD59 CD81 CFB CFH CFHR5 CFI CLU CPB2 CPN1 CPN2 ELANE F2 GPR77 LOC100336868 LOC107131209 LOC519737 LOC616002 SERPING1 VTN	Bos taurus (cattle)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial CPNE3 protein Copine 7 Copine-1 Copine-6	A0A3Q1MFM9 A5PJY9 F1MZS0 Q08DB4 Q2KHY1	AGK CPNE1 CPNE3 CPNE6 CPNE7	Bos taurus (cattle)
Synthesis of PA	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha 1-acyl-sn-glycerol-3-phosphate acyltransferase delta 1-acyl-sn-glycerol-3-phosphate acyltransferase 1-acylglycerol-3-phosphate O-acyltransferase 3 1-acylglycerol-3-phosphate O-acyltransferase 5 1-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta) Cytosolic phospholipase A2 DDHD domain containing 1 DDHD domain containing 2 Dihydroxyacetone phosphate acyltransferase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Glycerol-3-phosphate acyltransferase 3 Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase, mitochondrial LPCAT4 protein Lipase H Lysophosphatidic acid phosphatase type 6 Lysophosphatidylcholine acyltransferase 1 Mitochondrial cardiolipin hydrolase Mitoguardin 1 Mitoguardin 2 PLA2G12A protein Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase Phospholipase Secretory phospholipase A2 receptor alkaline phosphatase	A0A3Q1LQH8 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MMR4 A0A3Q1MNU5 A0A3S5ZPU2 A0A452DJJ3 A0JNE8 A4IFJ5 A5D7L0 A6H757 A6H7D4 A6QLU1 A6QQR7 E1BE10 E1BGF8 E1BGU4 E1BJE3 F1MDT6 F1MG30 F1MLW9 F1MNB3 F1MSG5 F1MSS2 F1MTK4 F1MXA8 F1MZS9 G5E5P6 P00593 P49259 Q1JPG0 Q56JZ2 Q5EA60 Q95JH2	ACP6 AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 AGPAT6 CPLA2 DDHD1 DDHD2 FAM73B GNPAT GPAM GPAT2 GPAT3 GPAT4 GPD1 GPD1L GPD2 LIPH LOC516378 LOC613966 LPCAT1 LPCAT4 MIGA1 MIGA2 PLA2G12A PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2R1 PLD1 PLD2 PLD6	Bos taurus (cattle)
The activation of arylsulfatases	ARSB protein ARSE protein Arylsulfatase A Arylsulfatase G Arylsulfatase K Arylsulfatase family member H Arylsulfatase family member I Formylglycine-generating enzyme Inactive C-alpha-formylglycine-generating enzyme 2 Steroid sulfatase	A0A3Q1LZ44 A5D7J7 A6QLZ3 E1BIN3 F1N665 G3N2T7 Q08DD1 Q0P5L5 Q148F3 Q58CP2	ARSA ARSB ARSE ARSG ARSH ARSI ARSK ARSL STS SUMF1 SUMF2	Bos taurus (cattle)
RHOD GTPase cycle	A-kinase anchoring protein 12 Adducin 3 Adenosine 5'-monophosphoramidase HINT2 Alpha-actinin-1 Anion exchange protein Ankyrin repeat and FYVE domain containing 1 CPNE8 protein Caveolin-1 DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 2 Diaphanous related formin 3 EF-hand domain-containing protein D2 EMD protein Family with sequence similarity 62 (C2 domain containing), member A Filamin A interacting protein 1 Golgin A2 Lamin B1 Lectin, mannose binding 1 Melanoma cell adhesion molecule Motile sperm domain containing 2 P21 (RAC1) activated kinase 6 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plexin A1 Plexin B1 Progesterone receptor membrane component 2 RNA binding motif protein 39 Rac GTPase activating protein 1 Ras homolog family member D Rho GTPase activating protein 12 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 STEAP3 metalloreductase Starch binding domain 1 Torsin-1A-interacting protein 1 Vang-like protein Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A3Q1LLI7 A0A3Q1LNB6 A0A3Q1LNG7 A0A3Q1LPT9 A0A3Q1LTM9 A0A3Q1LUD9 A0A3Q1LWV5 A0A3Q1LWZ4 A0A3Q1M0A2 A0A3Q1M6Y9 A0A3Q1MD15 A0A3Q1MRR8 A0A3Q1MSA1 A0A3Q1MSB2 A0A3Q1MZP2 A0A3Q1N078 A0A3Q1NDE1 A0JN43 A2VDZ9 A5D784 A5D7A0 A6QQV8 E1B7F6 E1B801 E1BA03 E1BAJ4 E1BFR4 E1BHQ9 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNR7 F1MY55 F1N4E5 F1N7C7 F1N7Q8 F6QJJ8 F6RWK1 G3MWI1 P23726 P23727 P79132 Q3B7N2 Q3SX08 Q8SQ21	ACTN1 ADD3 AKAP12 ANKFY1 ARHGAP1 ARHGAP12 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 CAV1 CPNE8 DEPDC1B DIAPH1 DIAPH2 DIAPH3 EFHD2 EMD ESYT1 FAM62A FILIP1 GOLGA2 HINT2 LBR LMAN1 LMNB1 MCAM MOSPD2 PAK5 PAK6 PGRMC2 PIK3R1 PIK3R2 PLXNA1 PLXNB1 RACGAP1 RBM39 RHOD SLC4A7 STBD1 STEAP3 SWS1 TOR1AIP1 VANGL1 VAPB VRK2	Bos taurus (cattle)
Complex I biogenesis	Acyl carrier protein Acyl-CoA dehydrogenase family member 9 Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Cytochrome c oxidase assembly factor 1 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 NADH NUBP iron-sulfur cluster assembly factor, mitochondrial Protein arginine methyltransferase NDUFAF7 Transmembrane protein 126B Transmembrane protein 186	A0A3Q1LID6 A0A3Q1LW79 A0A3Q1M7B1 A0A3Q1M8N8 A0A3Q1MBM6 A0A3Q1MG52 A0A3Q1MP25 A0A3Q1N0E1 A0A452DIB4 A4FUH5 A7YVD7 E1BAZ2 E1BCS4 E1BE32 E1BEC7 F1MJQ5 F1MQP4 F1MS25 G3X6L0 P03898 P03910 P03924 P04394 P15690 P17694 P23934 P23935 P34943 P42026 P42028 P42029 Q02365 Q02367 Q02368 Q02369 Q02370 Q02371 Q02372 Q02373 Q02374 Q02375 Q02376 Q02377 Q02379 Q02380 Q02827 Q05752 Q0II32 Q24JZ0 Q2HJI2 Q3SX05 Q5EA03 Q6QTH0 Q6QTH1 Q85BD6 Q8HXG5 Q8HXG6 Q95KV7	ACAD9 CI-B14-5A COA1 ECSIT GRIM19 HRPAP20 LOC101906178 MGC152111 MT-ND3 MT-ND4 MT-ND6 MTND3 MTND4 MTND6 NADH3 NADH4 NADH6 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA13 NDUFA2 NDUFA3 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF1 NDUFAF2 NDUFAF3 NDUFAF4 NDUFAF5 NDUFAF6 NDUFAF7 NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NUBPL TIMMDC1 TMEM126B TMEM186 UQOR22	Bos taurus (cattle)
FCGR activation	Fc fragment of IgG receptor IIb Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1M3L6 A0A3Q1MHG9 A0A3Q1MYA3 A0A3S5ZP99 A0JNB0 A5PKG9 A7MB57 E1BIM8 F1MHH9 F1N261 G3N0V0 G8JL01 P79107 Q0VCU4	CD247 CD3G FCGR1A FCGR2B FCGR3 FCGR3A FCGRIII FGR FYN LYN SRC SYK YES1	Bos taurus (cattle)
PI-3K cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type	A0A3Q1MPT9 A0MTF4 A6QLU3 D8KXU9 E1B7I9 E1BJU2 E1BP37 F1MHC6 F1N339 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P23727 P32871 Q3T0F9	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 FRS2 Fgf4 GAB1 GRB2 HBGF-1 PIK3CA PIK3R1 PTPN11	Bos taurus (cattle)
Phase 0 - rapid depolarisation	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like EF-hand domain-containing protein Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor RAN guanine nucleotide release factor Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel regulatory subunit beta-3 Sodium channel subunit beta-1 Sodium channel subunit beta-4 Sodium voltage-gated channel beta subunit 2 Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit calcium/calmodulin-dependent protein kinase	A0A3Q1LKG2 A0A3Q1LLX7 A0A3Q1MKC7 A0A3Q1MR28 A0A3Q1NE86 E1B757 E1B9G2 E1BHM6 E1BIG3 E1BLK4 E1BLM4 F1MHP0 F1MLH6 F1MV40 F1MW14 F1MX37 F1N5T3 F6QLW0 M0QVY7 M0QW12 Q08E08 Q17QN4 Q2HJF7 Q2KI11 Q3MHJ9 Q9MZL5 Q9MZL7	CACNA1C CACNA2D2 CACNB1 CACNB2 CACNG4 CACNG6 CACNG7 CACNG8 CALM CAMK2A CAMK2B CAMK2D FGF12 FGF13 FGF14 RANGRF SCN11A SCN1A SCN1B SCN2B SCN3A SCN3B SCN4B SCN5A SCN8A SCN9A	Bos taurus (cattle)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Calmodulin-like EF-hand domain-containing protein Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatase and tensin homolog Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase C epsilon 1 Phospholipase D family member 4 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A3Q1LJT8 A0A3Q1LJY0 A0A3Q1LNH2 A0A3Q1MMD9 A0A3Q1MR28 A4FV33 E1BB73 E1BBJ7 E1BJE0 E1BLB5 F1MBY5 F1MDX9 F1MLH6 F1MN32 F1MSD7 F1MTE8 F1MYF9 G3N3D6 P0C0T1 P10894 P10895 Q1RML2	CALM INPP5B INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKB ITPKC OCRL PLCB1 PLCB4 PLCD1 PLCD3 PLCE1 PLCG1 PLCG2 PLCH1 PLCZ PLCZ1 PLD4 PTEN	Bos taurus (cattle)
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A6QNL0 C4T7Z1 E1BIR9 Q2LGB7 Q6WCD5	CD14 LY96 MD-2 SARM1 TICAM2 TLR4 TRAM	Bos taurus (cattle)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Caspase-3 Catenin beta-1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoplakin Occludin Plakophilin 1 Tight junction protein 1 Tight junction protein 2	A0A3Q1MEH9 A0A3Q1MSS6 A2VE81 E1BKT9 E1BM91 F1MB04 F1MFC2 F1MIW8 F1N2D3 G3N156 Q0VCX4	CASP3 CDH1 CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2	Bos taurus (cattle)
Signaling by ERBB4	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase	A0A3Q1MKB4 A2VE27 A6QR62 E1BBE2 E1BIN8 F1MPD0 F1MS28 G3N104	BTC ERBB3 ERBB4 EREG HBEGF NRG1 NRG2 NRG3	Bos taurus (cattle)
Acyl chain remodelling of PI	Cytosolic phospholipase A2 Lysophospholipid acyltransferase 7 PLA2G12A protein Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor	A0A3Q1LYR5 A0A3Q1MNU5 A0A3Q1NMD6 A4IFJ5 A5D7L0 E1BGU4 F1MG30 F1MNU5 F1MSG5 P00593 P49259 Q0VCY6 Q56JZ2 Q9GL30	CPLA2 LENG4 LOC613966 MBOAT7 OACT7 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2R1 PLBD1	Bos taurus (cattle)
Scavenging of heme from plasma	Albumin Hemoglobin subunit alpha Hemoglobin subunit beta Hemopexin LDL receptor related protein 1 Scavenger receptor cysteine-rich type 1 protein M130	A0A140T897 A0A452DI25 E1BGJ0 P01966 P02070 P85521	ALB CD163 HBA HBB HPX LRP1 M130	Bos taurus (cattle)
Dopamine receptors	D(1A) dopamine receptor D(1B) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor	F1N454 F1N4I3 G3X8D2 Q95136	D1AR DRD1 DRD2 DRD3 DRD5	Bos taurus (cattle)
Regulation of FZD by ubiquitination	Frizzled class receptor 5 Frizzled class receptor 8 Frizzled-6 Leucine rich repeat containing G protein-coupled receptor 5 Low-density lipoprotein receptor-related protein Low-density lipoprotein receptor-related protein Polyubiquitin-B Polyubiquitin-C Protein Wnt R-spondin 1 R-spondin 2 R-spondin 4 R-spondin-3 RING-type E3 ubiquitin transferase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A3Q1LTW2 A0A3Q1MA92 A0A452DIK6 E1BNT4 F1MDE1 F1ME23 F1MGM1 F1MH47 F1MP23 F1N1K8 F6RLD1 P0CG53 P0CH28 P62992 P63048 Q0IIM6 Q1RMU1	FZD5 FZD6 FZD8 LGR5 LRP5 LRP6 RNF43 RPS27A RSPO1 RSPO2 RSPO3 RSPO4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP8 WNT3A	Bos taurus (cattle)
HS-GAG biosynthesis	Agrin Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Exostosin glycosyltransferase 2 Exostosin-1 Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Heparan sulfate 2-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Solute carrier family 35 member D2 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Syndecan-1 Syndecan-2 Syndecan [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase	A0A3Q1LS54 A0A3Q1LTY7 A0A3Q1LZ29 A0A3Q1M8D2 A0A3S5ZPA0 A5D7I4 A8E4L2 E1B729 E1BCG5 E1BJP5 E1BKJ2 E1BKQ1 E1BKS1 E1BM02 E1BNJ7 E1BP03 F1MCX1 F1MMN3 F1MZX8 Q08DZ5 Q0VCB5 Q0VD21 Q3ZBZ6 Q58DD4	AGRN EXT1 EXT2 GPC1 GPC2 GPC3 GPC4 GPC5 HS2ST1 HS3ST1 HS3ST2 HS3ST3A1 HS3ST3B1 HS3ST5 HS3ST6 HS6ST2 HS6ST3 NDST1 NDST2 NDST4 SDC1 SDC2 SDC4 SLC35D2	Bos taurus (cattle)
Trafficking and processing of endosomal TLR	Cathepsin B Cathepsin K Cathepsin S Endoplasmin Legumain Procathepsin L Protein canopy homolog 3 Toll like receptor 3 Toll like receptor 7 Toll-like receptor 9 Unc-93 homolog B1, TLR signaling regulator	A0A140T8D4 A0A3Q1MK24 A0A3S5ZPK8 A5H631 E1BBH4 P07688 P25326 P25975 Q0P5N1 Q5E968 Q95M18	CNPY3 CTSB CTSK CTSL CTSL1 CTSS GRP94 HSP90B1 HSPC4 LGMN TLR3 TLR7 TLR9 TRA1 UNC93B1	Bos taurus (cattle)
WNT ligand biogenesis and trafficking	Protein Wnt-2 Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Sorting nexin-3 Transmembrane emp24 domain-containing protein 5 Vacuolar protein sorting-associated protein 26A Vacuolar protein sorting-associated protein 29 Vacuolar protein sorting-associated protein 35 Wnt ligand secretion mediator	A0A140T847 A0A3Q1LTW2 A0A3Q1M1A0 A0A3Q1MGH5 A0A3Q1MJR6 A0A3Q1MQ82 A4D7S0 A6H6X8 E1BDG5 E1BEN9 E1BKL2 F1MEW8 F1MHG3 F1MK64 F1MN70 F1N4C0 F1N5R1 F1N6L8 Q0VD53 Q1RMH8 Q2HJG5 Q2KJ84 Q3T0M0	SNX3 TMED5 VPS26A VPS29 VPS35 WLS WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT6 WNT7A WNT7B WNT8A WNT8B WNT9B	Bos taurus (cattle)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase Angiotensin-converting enzyme Angiotensinogen Carboxylic ester hydrolase Carboxypeptidase A3 Carboxypeptidase B2 Carboxypeptidase B Cathepsin D Cathepsin Z Neprilysin Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Renin receptor renin	A0A3Q1LTF9 A0A3Q1MQJ1 A0A452DJE0 E1B8U1 E1BAD2 E1BIP7 E1BK06 E1BPL8 F1MEM5 F1MMR6 F1MZL4 P00732 P01017 P05689 P81134 Q2KIG3	ACE2 AGT ATP6AP2 ATP6IP2 CES1 CPA3 CPB CPB1 CPB2 CTSD CTSZ ENPEP LOC100139881 LOC509956 LOC540321 LOC617313 MME REN SERPINA8	Bos taurus (cattle)
Interleukin-7 signaling	Bromodomain and WD repeat domain containing 1 Cytokine receptor common subunit gamma Histone H3.1 Histone H3.2 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphoinositide-3-kinase regulatory subunit 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Signal transducer and activator of transcription Transcription activator BRG1 Tyrosine-protein kinase Tyrosine-protein kinase	A0A140T878 A7Z019 E1BEL4 E1BPM3 F1MDQ5 F1MJE0 F1MTQ0 F1MX38 F1MYE0 F1N0D6 P23726 P23727 P26895 P68432 P84227 Q95115 Q95118	BAF190A BRG1 BRWD1 IL2RG IL7 IL7R IRS1 IRS2 JAK1 JAK3 MGF PIK3R1 PIK3R2 PIK3R3 SMARCA4 SNF2B SNF2L4 STAT3 STAT5A STAT5B	Bos taurus (cattle)

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