GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **557** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Digestion of dietary carbohydrate	Alpha-amylase Lactase Maltase-glucoamylase 2 (putative) Sucrase-isomaltase chitinase	E1BGH5 E1BK89 F1MH27 F1MP21 G3N3S2	CHIA LCT LOC539383 MGAM2 SI	Bos taurus (cattle)	G58161NS G74621DY G93924TT G96370VA
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Corticosteroid-binding globulin Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase steroid 11beta-monooxygenase steroid 11beta-monooxygenase steroid 11beta-monooxygenase	E1BF81 F1MG97 F1MU47 F1MWH3 F1N3U0 P00191 P01190 P05185 P14893	CBG CYP11B1 CYP17 CYP17A1 CYP21 CYP21A1 CYP21A2 HSD11B2 HSD3B LOC112449566 POMC SERPINA6	Bos taurus (cattle)
Opsins	Long-wave-sensitive opsin 1 Melanopsin Opsin 5 RPE-retinal G protein-coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin Short-wave-sensitive opsin 1	E1BEK2 E1BNN4 F1MR98 P02699 P47803 P51490 Q9BGI7	BCP OPN1LW OPN1SW OPN4 OPN5 RCP RGR RHO RRH	Bos taurus (cattle)
Stabilization of p53	Cellular tumor antigen p53 Checkpoint kinase 2 E3 ubiquitin-protein ligase Mdm2 Serine-protein kinase ATM	E1BEI6 F1MYE6 F6R5E4 P67939	ATM CHEK2 MDM2 TP53	Bos taurus (cattle)
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium channel subfamily K member Potassium two pore domain channel subfamily K member 16	E1BEH1 Q8HZT2	KCNK16 KCNK17	Bos taurus (cattle)
Costimulation by the CD28 family	Inducible T cell costimulator ligand Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3	E1BCU8 F1MDQ5 P23726 P23727 P32871 Q58DF9	ICOS ICOSLG PIK3CA PIK3R1 PIK3R2 PIK3R3	Bos taurus (cattle)
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase Tyrosine-protein kinase	E1BCP6 F1MEQ7 F1MJE0 F1N261	EPOR IRS2 JAK2 LYN	Bos taurus (cattle)
Ca activated K+ channels	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-activated potassium channel subunit beta Calcium-activated potassium channel subunit beta Potassium calcium-activated channel subfamily N member 1 Potassium calcium-activated channel subfamily N member 2 Potassium calcium-activated channel subfamily N member 3	E1BCE5 E1BGY2 E1BHB0 F1N467 Q1RMW7 Q28067 Q28204	KCNMA KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNN1 KCNN2 KCNN3	Bos taurus (cattle)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	E1BC78 P01217 P04651 P49884	ATAD2 CGA ESR ESR1 LHB NR3A1	Bos taurus (cattle)
Arachidonate production from DAG	Lysophosphatidylserine lipase ABHD12 Monoacylglycerol lipase ABHD6 sn-1-specific diacylglycerol lipase sn-1-specific diacylglycerol lipase	E1BBV2 F6RA94 Q08DW9 Q1LZ86	ABHD12 ABHD6 DAGLA DAGLB	Bos taurus (cattle)
Non-integrin membrane-ECM interactions	Tyrosine-protein kinase receptor receptor protein-tyrosine kinase	E1BBP4 F1MIE0	DDR1 DDR2	Bos taurus (cattle)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin 1 Cardiotrophin like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Interleukin 6 cytokine family signal transducer LIF receptor subunit alpha Leukemia inhibitory factor Oncostatin M Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	E1BAT3 E1BCP6 E1BD36 E1BD91 E1BFH9 F1MCX4 F1MLR4 F1N0D6 F1N366 G3MXT9 Q27956	CLCF1 CNTF CNTFR CTF1 IL6ST JAK1 JAK2 LIF LIFR OSM TYK2	Bos taurus (cattle)
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha	E1BA29 F1MSD7 F1N2V3 P10894 P38408 P38409	GNA11 GNA14 GNA15 GNAQ PLCB1 PLCB4	Bos taurus (cattle)
RUNX1 regulates estrogen receptor mediated transcription	Core-binding factor subunit beta Estrogen receptor Runt-related transcription factor	E1B9S8 E1BAD4 P49884	CBFB ESR ESR1 NR3A1 RUNX1	Bos taurus (cattle)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member	E1B9M4 Q0P5A0	KCNK1 KCNK7	Bos taurus (cattle)
Activation of the phototransduction cascade	Cyclic nucleotide gated channel subunit beta 1 Cyclic nucleotide-gated channel alpha-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Phosphodiesterase Phosphodiesterase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin	E1B957 E1BK80 F1MTS7 P02698 P02699 P04695 P04972 P62871 Q00194	CNCG CNCG1 CNGA1 CNGB1 GNAT1 GNB1 GNGT1 PDE6A PDE6B PDE6G PDEG RHO	Bos taurus (cattle)
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin 6 cytokine family signal transducer Interleukin 6 receptor Interleukin-6 Mitogen-activated protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	E1B8P9 E1BCP6 E1BD36 E1BJQ3 F1MCX4 F1N0D6 F1N339 P26892 P48734 Q0VD16	CDC2 CDK1 CDKN1 IL6 IL6R IL6ST JAK1 JAK2 MAP2K1 MAPK3 PTPN11 TYK2	Bos taurus (cattle)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	Catenin beta-1 Interferon regulatory factor 3 histone acetyltransferase histone acetyltransferase	E1B8D6 F1MD32 Q0VCX4 Q4JF28	CREBBP CTNNB1 EP300 IRF3	Bos taurus (cattle)
MyD88 cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	E1B847 Q3SX05 Q3ZCC3	ECSIT MAP3K1 TRAF6	Bos taurus (cattle)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	E1B847 Q3SX05 Q3ZCC3	ECSIT MAP3K1 TRAF6	Bos taurus (cattle)
Platelet homeostasis	P2X purinoceptor 4 P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase 2, cytoplasmic	E1B742 E1BIH1 E1BIP1 F1MUF3 F1MVZ6 F1N7A9 P79106 Q5E9U1	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2	Bos taurus (cattle)
Electric Transmission Across Gap Junctions	Gap junction delta-2 protein Gap junction gamma-1 protein Gap junction protein Pannexin Pannexin	D7R519 E1BLU3 G5E5X7 Q2HJ66 Q866T7	GJA10 GJA7 GJA9 GJC1 GJD2 PANX PANX1 PANX2	Bos taurus (cattle)
Heme signaling	Apolipoprotein A-I Apolipoprotein B BTB domain and CNC homolog 1 Exportin 1 Hemoglobin subunit alpha Hemoglobin subunit beta Lymphocyte antigen 96 MAF bZIP transcription factor K Progesterone receptor membrane component 2 Proton-coupled folate transporter Toll-like receptor 4	C4T7Z1 E1BB01 E1BE98 E1BJL3 E1BNR0 F6QJJ8 P01966 P02070 P15497 Q05B81 Q6WCD5	APOA1 APOB BACH1 HBA HBB HCP1 LY96 MAFK MD-2 PCFT PGRMC2 SLC46A1 TLR4 XPO1	Bos taurus (cattle)
Neurotransmitter clearance	Solute carrier family 22 member 1 Solute carrier family 22 member 2	A7MBE0 E1BHW6	OCT1 SLC22A1 SLC22A2	Bos taurus (cattle)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	A7MBE0 E1BHW6 F1MXY3	OCT1 SLC22A1 SLC22A2 SLC22A3	Bos taurus (cattle)

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