GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID ▲
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase domain 15 ADAM metallopeptidase domain 8 ADAM metallopeptidase with thrombospondin type 1 motif 5 Aggrecan core protein Alpha-2-macroglobulin Basigin Brevican core protein CD44 antigen Cadherin-1 Cadherin-1 Calpain 10 Calpain 11 Calpain 12 Calpain 13 Calpain 14 Calpain 15 Calpain 5 Calpain 6 Calpain 9 Calpain catalytic domain-containing protein Calpain catalytic domain-containing protein Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-3 Calpastatin Cathepsin G Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Elastase, neutrophil expressed HtrA serine peptidase 1 Kallikrein D Matrix metallopeptidase 11 Matrix metallopeptidase 12 Matrix metallopeptidase 19 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Nidogen 1 Opticin Procathepsin L Secreted phosphoprotein 1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Transmembrane serine protease 6 interstitial collagenase	A0A8I3MCQ8 A0A8I3MDF9 A0A8I3MEZ7 A0A8I3MGS0 A0A8I3MM49 A0A8I3MND9 A0A8I3MS95 A0A8I3MTX4 A0A8I3MUT8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N8Z0 A0A8I3NAW1 A0A8I3NBM1 A0A8I3NET5 A0A8I3NF92 A0A8I3NG54 A0A8I3NHT2 A0A8I3NK04 A0A8I3NLH7 A0A8I3NNE0 A0A8I3NQ99 A0A8I3P0M4 A0A8I3P0U1 A0A8I3P1W2 A0A8I3P478 A0A8I3P4K7 A0A8I3P533 A0A8I3P8U9 A0A8I3PAG9 A0A8I3PCF8 A0A8I3PED9 A0A8I3PJW4 A0A8I3PMD6 A0A8I3PRM5 A0A8I3PVS1 A0A8I3Q3A2 A0A8I3Q5H9 A0A8I3QPC2 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3S3W1 A0A8I3S676 A0A8I3S9F9 A0A8I3SBJ8 E2FGH7 F1PAA9 Q29393 Q6Y4Q5 Q8MJD1 Q9GL24	A2M ACAN ADAM10 ADAM15 ADAM8 ADAMTS4 ADAMTS5 BCAN BSG CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS1 CAST CD44 CDH1 CTSG CTSL CTSL1 CTSS DCN DCN1C ELA2 ELANE HTRA1 KLK7 KLND MMP1 MMP11 MMP12 MMP13 MMP14 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 NID1 OPTC SCUBE1 SCUBE3 SPP1 TMPRSS6	Canis familiaris (dog)
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Vav guanine nucleotide exchange factor 1 cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3N974 A0A8I3NA65 A0A8I3NBM3 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PBB4 A0A8I3PMT9 A0A8I3PRW9 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q4Y8 A0A8I3Q525 A0A8I3RVE7 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3N2 P48749 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB IL3 IL5 IL5RA JAK2 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ	Canis familiaris (dog)
Transport of RCbl within the body	ATP binding cassette subfamily D member 4 CD320 molecule LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Lysosomal cobalamin transport escort protein LMBD1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Transcobalamin-2 Transcobalamin-like C-terminal domain-containing protein	A0A8I3N1I8 A0A8I3N584 A0A8I3NS16 A0A8I3P9U6 A0A8I3PAV5 A0A8I3PKW5 A0A8I3Q758 A0A8I3S4Z0 Q6UR05	ABCC1 CD320 LDLRAP1 LMBRD1 LOC119869278 LRP2 MRP1 TCN1 TCN2	Canis familiaris (dog)
G alpha (i) signalling events	5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 5A Adenosine receptor A1 Adenosine receptor A3 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Amyloid-beta A4 protein Angiotensinogen Annexin B1 bradykinin receptor B2 bradykinin receptor Bitter taste receptor T2R43 C-C chemokine receptor type 5 C-C motif chemokine 25 C-C motif chemokine 4 C-C motif chemokine receptor 10 C-C motif chemokine receptor 7 C-C motif chemokine receptor 9 C-C motif chemokine C-C motif chemokine C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 3 C-X-C chemokine receptor type 6 C-X-C motif chemokine 10 C-X-C motif chemokine 16 C-X-C motif chemokine ligand 11 C-X-C motif chemokine receptor 5 C-X-C motif chemokine C-X-C motif chemokine C-X3-C motif chemokine ligand 1 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 CX3C chemokine receptor 1 Cannabinod receptor Chemokine (C-C motif) receptor 1 Complement C3 Complement C5 D(3) dopamine receptor Extracellular calcium-sensing receptor G protein signaling modulator 1 G protein signaling modulator 3 G protein subunit alpha transducin 2 G protein subunit alpha transducin 3 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled receptor 17 G protein-coupled receptor 183 G protein-coupled receptor 37 like 1 G protein-coupled receptor 37 G protein-coupled receptor 55 G-protein coupled estrogen receptor 1 G-protein coupled receptor 81 G-protein coupled receptors family 1 profile domain-containing protein Galanin peptides Galanin receptor 1 Galanin receptor 2 Galanin receptor 3 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Glutamate metabotropic receptor 2 Glutamate metabotropic receptor 4 Glutamate metabotropic receptor 6 Glutamate metabotropic receptor 7 Glutamate metabotropic receptor 8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine receptor H4 Interleukin-8 Kappa-type opioid receptor Kininogen 1 Long-wave-sensitive opsin 1 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melatonin receptor 1B Melatonin receptor type 1A Metabotropic glutamate receptor 3 Mu-type opioid receptor Multifunctional fusion protein Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor N-arachidonyl glycine receptor Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-S Neuromedin-U-25 Neuropeptide B Neuropeptide W Neuropeptide Y receptor Y4 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptide Y Neuropeptides B and W receptor 1 Opioid receptor delta 1 Opsin 3 Opsin 5 Oxoglutarate receptor 1 Pancreatic polypeptide Peptide YY Pro-MCH Pro-opiomelanocortin Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Proenkephalin-A Proenkephalin-B Prosaposin Prostaglandin D2 receptor 2 Prostaglandin E2 receptor EP3 subtype Purinergic receptor P2Y12 Purinergic receptor P2Y14 Purkinje cell protein 2 RGS domain-containing protein Regulator of G protein signaling 11 Regulator of G protein signaling 12 Regulator of G protein signaling 13 Regulator of G protein signaling 17 Regulator of G protein signaling 18 Regulator of G protein signaling 19 Regulator of G protein signaling 21 Regulator of G protein signaling 3 Regulator of G protein signaling 5 Regulator of G protein signaling 6 Regulator of G protein signaling 7 Regulator of G-protein signaling 16 Regulator of G-protein signaling 1 Regulator of G-protein signaling 4 Regulator of G-protein signaling 8 Regulator of G-protein signaling 9 Relaxin family peptide receptor 3 Relaxin-3 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin Short-wave-sensitive opsin 1 Somatostatin receptor 3 Somatostatin receptor 5 Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin Sphingosine-1-phosphate receptor 2 Sphingosine-1-phosphate receptor 3 Sphingosine-1-phosphate receptor 4 Sphingosine-1-phosphate receptor 5 Succinate receptor 1 Taste 1 receptor member 1 Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Type-2 angiotensin II receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A0F6TN93 A0A8I3M9P4 A0A8I3MA93 A0A8I3MBK3 A0A8I3MC04 A0A8I3ME07 A0A8I3ME61 A0A8I3MGQ1 A0A8I3MHA7 A0A8I3MKF9 A0A8I3MM75 A0A8I3MM87 A0A8I3MN59 A0A8I3MNZ2 A0A8I3MPN0 A0A8I3MQK6 A0A8I3MQM8 A0A8I3MRI6 A0A8I3MRZ4 A0A8I3MRZ6 A0A8I3MS01 A0A8I3MU83 A0A8I3MVK0 A0A8I3MX13 A0A8I3MXL9 A0A8I3MXY0 A0A8I3MYE3 A0A8I3MYF9 A0A8I3N081 A0A8I3N0P5 A0A8I3N125 A0A8I3N207 A0A8I3N302 A0A8I3N349 A0A8I3N4S6 A0A8I3N4Y4 A0A8I3N5K9 A0A8I3N640 A0A8I3N6A0 A0A8I3N6I2 A0A8I3NAD1 A0A8I3NAS6 A0A8I3ND24 A0A8I3NDC4 A0A8I3NDU8 A0A8I3NDZ2 A0A8I3NEA4 A0A8I3NGZ9 A0A8I3NHT7 A0A8I3NHV8 A0A8I3NKU5 A0A8I3NLJ6 A0A8I3NMN5 A0A8I3NMV4 A0A8I3NNN1 A0A8I3NNT7 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NPT8 A0A8I3NPW0 A0A8I3NQ26 A0A8I3NQA0 A0A8I3NQV1 A0A8I3NR19 A0A8I3NVC1 A0A8I3NWG9 A0A8I3NXJ3 A0A8I3NYI6 A0A8I3NZN3 A0A8I3P0A1 A0A8I3P108 A0A8I3P1U0 A0A8I3P2E9 A0A8I3P3I1 A0A8I3P4V6 A0A8I3P5Y8 A0A8I3P7L3 A0A8I3P831 A0A8I3P8G7 A0A8I3P9H6 A0A8I3PBD4 A0A8I3PBE4 A0A8I3PCM1 A0A8I3PDF9 A0A8I3PDW8 A0A8I3PE74 A0A8I3PEX2 A0A8I3PH14 A0A8I3PIK0 A0A8I3PIX9 A0A8I3PJF2 A0A8I3PJU6 A0A8I3PM36 A0A8I3PM57 A0A8I3PMD7 A0A8I3PNM4 A0A8I3PP20 A0A8I3PPP9 A0A8I3PPR9 A0A8I3PQY2 A0A8I3PRQ9 A0A8I3PS75 A0A8I3PV05 A0A8I3PVZ2 A0A8I3PWB5 A0A8I3PXC2 A0A8I3PXL4 A0A8I3PYB5 A0A8I3PZU6 A0A8I3Q0H0 A0A8I3Q0K2 A0A8I3Q2D1 A0A8I3Q2F2 A0A8I3Q2S6 A0A8I3Q4F7 A0A8I3Q7L4 A0A8I3Q7S8 A0A8I3Q8Q0 A0A8I3Q8T3 A0A8I3QE57 A0A8I3QV74 A0A8I3RPW6 A0A8I3RR88 A0A8I3RSE4 A0A8I3RSK6 A0A8I3RT67 A0A8I3RTH5 A0A8I3RTK9 A0A8I3RTX6 A0A8I3RUS6 A0A8I3RVM8 A0A8I3RW80 A0A8I3RWJ1 A0A8I3RWZ6 A0A8I3RXC1 A0A8I3RXP5 A0A8I3RYN2 A0A8I3RZ84 A0A8I3RZH5 A0A8I3S3R7 A0A8I3S583 A0A8I3S5G1 A0A8I3S5I1 A0A8I3S656 A0A8I3S6A4 A0A8I3S6V0 A0A8I3S7S8 A0A8I3S925 A0A8I3S929 A0A8I3SA57 A0A8I3SBF9 A0A8I3SBJ6 A0A8I3SCV7 A2SXS6 B9UM26 E2RKA3 E2RQ21 E2RTH0 O02813 O18914 O62729 O97564 P11616 P38400 P41324 P49670 P62872 P63210 P79147 P79250 Q28300 Q28309 Q2ABC7 Q2ABD0 Q2ABD1 Q2ABD4 Q2ABD5 Q2ABD6 Q2ABD8 Q2ABE0 Q49LX5 Q5ECR9 Q5KSV9 Q5XXR2 Q68A93 Q68AZ0 Q8MIP6 Q9BDQ4 Q9BDQ5	ADORA1 ADORA3 ADRA2A ADRA2B ADRA2C AGT AGTR2 ANXA1 APP BDKRB1 BDKRB2 Bdkrb2 C3 C3AR1 C5 C5AR1 CAFA-T2R43 CASR CB2 CCL19 CCL23 CCL25 CCL28 CCL4 CCR1 CCR10 CCR5 CCR7 CCR9 CHRM2 CHRM4 CMKBR5 CNR2 CX3CL1 CX3CR1 CXCL10 CXCL11 CXCL13 CXCL16 CXCL6 CXCL8 CXCR2 CXCR3 CXCR5 CXCR6 DRD3 FPR2 GABBR1 GABBR2 GAL GALR1 GALR2 GALR3 GNAI1 GNAI2 GNAI3 GNAT1 GNAT2 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 GPER1 GPR17 GPR18 GPR183 GPR31 GPR37 GPR37L1 GPR55 GPSM1 GPSM2 GPSM3 GRM2 GRM3 GRM4 GRM6 GRM7 GRM8 HCAR1 HCAR2 HRH4 HTR1B HTR1D HTR1E HTR1F HTR5A IL8 KNG1 LOC100682759 LOC119863873 LPAR1 LPAR2 LPAR3 LPAR5 MCH MCHR1 MCHR2 MTNR1A MTNR1B NMS NMU NMUR1 NMUR2 NPB NPBWR1 NPY NPY1R NPY2R NPY4R NPY5 NPY5R OPN1LW OPN1SW OPN3 OPN5 OPRD1 OPRK1 OPRM1 OXER1 OXGR1 P2RY12 P2RY14 PCP2 PDYN PENK PMCH POMC PPBP PPY PSAP PTGDR2 PTGER3 PYY RCP RDC7 RGR RGS1 RGS11 RGS12 RGS13 RGS14 RGS16 RGS17 RGS18 RGS19 RGS20 RGS21 RGS3 RGS4 RGS5 RGS6 RGS7 RGS8 RGS9 RHO RLN3 RRH RXFP3 S1PR2 S1PR3 S1PR4 S1PR5 SCYA4 SRC SST SSTR1 SSTR2 SSTR3 SSTR5 SUCNR1 TAS1R1 TAS1R3 TAS2R1 TAS2R10 TAS2R3 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R5 TAS2R7 ccr9 cx3cl1 gpr81	Canis familiaris (dog)
Common Pathway of Fibrin Clot Formation	Antithrombin-III Coagulation factor V Coagulation factor X Coagulation factor XIII A chain Coagulation factor XIII B chain Protein C receptor Proteinase-activated receptor 1 Prothrombin Serpin domain-containing protein Serpin family A member 5 Serpin family D member 1 Thrombomodulin Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A8I3MGM0 A0A8I3MLH1 A0A8I3MQ40 A0A8I3NE44 A0A8I3NHZ1 A0A8I3P760 A0A8I3P7K7 A0A8I3PPY1 A0A8I3PQV5 A0A8I3PUT1 A0A8I3Q092 A0A8I3QAV8 A0A8I3S1X8 Q28278	F10 F13A1 F13B F2 F2R F5 PROC PROCR PROS1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 THBD	Canis familiaris (dog)
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A8I3N3U3 A0A8I3NGY1 A0A8I3NUU1 A0A8I3PS27 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3QSS9 A0A8I3S3D9 Q867B7	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1	Canis familiaris (dog)
FGFR3c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Polypeptide N-acetylgalactosaminyltransferase Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P0X5 A0A8I3PJY6 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GALNT3	Canis familiaris (dog)
Atorvastatin ADME	ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily B member 1 Cytochrome P450 3A12 Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Paraoxonase 3 Paraoxonase Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member	A0A8I3MQC6 A0A8I3N2I4 A0A8I3NMC0 A0A8I3NUI6 A0A8I3PAM3 A0A8I3PDF6 A0A8I3PU35 A0A8I3PV37 A0A8I3SCV5 P24463	ABCB1 ABCC2 CYP3A12 LOC119868939 LOC119875773 LOC119876349 PON1 PON3 SLCO1B2 SLCO1B3 SLCO2B1	Canis familiaris (dog)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase Angiotensin-converting enzyme Angiotensin-converting enzyme Angiotensinogen Carboxylesterase 5A Carboxypeptidase B1 Carboxypeptidase B2 Cathepsin D Cathepsin G Chymase Neprilysin Renin receptor Renin cathepsin X	A0A8I3NK04 A0A8I3NT46 A0A8I3P176 A0A8I3PJS4 A0A8I3PTV1 A0A8I3QCM1 A0A8I3RP60 A0A8I3RR88 A0A8I3RUJ7 A0A8I3S392 F5C3N2 P21842 Q4LAL9 Q6DYE7	ACE ACE2 AGT ATP6AP2 CES5A CMA1 CPA3 CPB2 CTSD CTSG CTSZ ENPEP MME REN	Canis familiaris (dog)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Procathepsin L Serpin family B member 13	A0A8I3MMH2 Q9GL24	CTSL CTSL1 SERPINB13	Canis familiaris (dog)
Lysosomal oligosaccharide catabolism	Alpha-mannosidase alpha-mannosidase beta-mannosidase	A0A8I3P3N3 A0A8I3PHW0 A0A8I3PSC3	MAN2B1 MAN2C1 MANBA	Canis familiaris (dog)	G00027MO G25577BM G28233ME G70323CJ G90333CG
HS-GAG degradation	Agrin Alpha-L-iduronidase Alpha-L-iduronidase Beta-galactosidase Beta-galactosidase Beta-glucuronidase Galactosidase beta 1 like Glypican 2 Glypican 4 Glypican 5 Glypican 6 Glypican-1 Glypican-3 Heparanase 2 (inactive) Heparanase Iduronate 2-sulfatase N-acetyl-alpha-glucosaminidase N-sulfoglucosamine sulfohydrolase Syndecan 4 Syndecan Syndecan	A0A8I3MPF1 A0A8I3MQQ0 A0A8I3MUC2 A0A8I3MXW0 A0A8I3N3H1 A0A8I3N3M6 A0A8I3NA03 A0A8I3NDU0 A0A8I3NJ98 A0A8I3NWG4 A0A8I3P4F5 A0A8I3P836 A0A8I3PLC3 A0A8I3Q139 A0A8I3Q4U0 A0A8I3Q662 A0A8I3QTG2 A0A8I3QZP4 Q01634 Q32KH3 Q9TRY9	AGRN GLB1 GLB1L GLB1L2 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GUSB HPSE HPSE2 IDS IDUA NAGLU SDC1 SDC3 SDC4 SGSH ids	Canis familiaris (dog)	G01550VL G09546QO
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Autocrine motility factor receptor Derlin Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Proteasome 26S subunit, ATPase 1 Transitional endoplasmic reticulum ATPase UBX domain protein 1 UV excision repair protein RAD23 Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A8I3MMN5 A0A8I3N153 A0A8I3N6X7 A0A8I3NFB9 A0A8I3NK06 A0A8I3NNJ9 A0A8I3NV83 A0A8I3PZS2 A0A8I3QYD0 A0A8I3RQN1 A0A8I3RW88 P63050	AMFR DERL1 ENGASE NGLY1 PSMC1 RAD23B RPS27A UBA52 UBB UBC UBCEP2 UBXN1 VCP	Canis familiaris (dog)	G03934XO G25577BM G28233ME G51034LA G86419OL
Keratan sulfate degradation	Aggrecan core protein Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Fibromodulin Galactosidase beta 1 like Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase Osteomodulin Proline and arginine rich end leucine rich repeat protein	A0A8I3MQQ0 A0A8I3MS95 A0A8I3MY15 A0A8I3NEJ3 A0A8I3P4B0 A0A8I3P684 A0A8I3PHJ7 A0A8I3PNW9 A0A8I3PS70 A0A8I3Q139 A0A8I3S110 A0A8I3S4Y4 Q9TRY9	ACAN FMOD GLB1 GLB1L GLB1L2 GNS HEXA HEXB KERA LUM OGN OMD PRELP	Canis familiaris (dog)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Glycosphingolipid catabolism	Acid ceramidase Alpha-galactosidase Arylsulfatase A Arylsulfatase B Arylsulfatase F Arylsulfatase G Arylsulfatase K Arylsulfatase L Arylsulfatase family member H Arylsulfatase family member I Arylsulfatase family member J Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Carboxypeptidase Ectonucleotide pyrophosphatase/phosphodiesterase 7 Galactocerebrosidase Galactosidase beta 1 like Ganglioside GM2 activator Glucosylceramidase beta 3 (gene/pseudogene) Glucosylceramidase Mannose-6-phosphate receptor, cation dependent Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sphingomyelin phosphodiesterase Steroid sulfatase Sulfatase modifying factor 1 Sulfatase modifying factor 2 Uncharacterized protein exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A8I3MQM8 A0A8I3MQQ0 A0A8I3MQZ3 A0A8I3MY15 A0A8I3MZE8 A0A8I3N2H8 A0A8I3NC41 A0A8I3NF27 A0A8I3NH12 A0A8I3NJQ3 A0A8I3NK36 A0A8I3NK85 A0A8I3NN43 A0A8I3NQ68 A0A8I3NUS9 A0A8I3NZ71 A0A8I3PAY1 A0A8I3PBB8 A0A8I3PGV9 A0A8I3PHI8 A0A8I3PN86 A0A8I3PNW9 A0A8I3PP93 A0A8I3PPB0 A0A8I3PT92 A0A8I3Q0D0 A0A8I3Q139 A0A8I3Q2D2 A0A8I3Q545 A0A8I3Q695 A0A8I3RTW7 A0A8I3RW96 A0A8I3RZ95 A0A8I3S3Z3 Q32KH0 Q32KI4 Q9TRY9	ARSA ARSB ARSF ARSG ARSH ARSI ARSJ ARSK ARSL ASAH1 ASAH2 CTSA ENPP7 GALC GBA1 GBA2 GBA3 GLA GLB1 GLB1L GLB1L2 GM2A HEXA HEXB M6PR NEU1 NEU2 NEU3 NEU4 PSAP SMPD1 SMPD2 SMPD3 SMPD4 STS SUMF1 SUMF2 arsb	Canis familiaris (dog)	G09546QO G27025MB G58161NS
CS/DS degradation	Alpha-L-iduronidase Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase Beta-hexosaminidase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase Iduronate 2-sulfatase Neurocan Versican core protein	A0A8I3MXW0 A0A8I3MY15 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NUF9 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3PI48 A0A8I3PNW9 Q01634 Q29393 Q32KH3 Q32KI4	ARSB BCAN BGN CSPG4 CSPG5 DCN DCN1C HEXA HEXB HYAL1 IDS IDUA NCAN VCAN arsb ids	Canis familiaris (dog)	G27025MB
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A8I3MQ54 A0A8I3MSC7 A0A8I3NN17 A0A8I3P237 A0A8I3P626 A0A8I3Q4Y1 A0A8I3Q7C5 A0A8I3RVI9 A0A8I3RZI7 A0A8I3S1Y7 A0A8I3SAK1	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT	Canis familiaris (dog)	G31080DL
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase Beta-hexosaminidase CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase Lymphatic vessel endothelial hyaluronan receptor 1 Sodium/hydrogen exchanger Stabilin 2	A0A8I3MHZ0 A0A8I3MY15 A0A8I3NBX1 A0A8I3NDU0 A0A8I3NYL9 A0A8I3PCF8 A0A8I3PI48 A0A8I3PNW9 A0A8I3Q0H4 A0A8I3RW87	CD44 CHP1 GUSB HEXA HEXB HMMR HYAL1 LYVE1 SLC9A1 STAB2	Canis familiaris (dog)	G35674CY
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	A0A8I3MYT1 A0A8I3N9C7 A0A8I3ND97 A0A8I3PVZ3 A0A8I3RTT3	ABCC5 CEMIP HAS1 HAS2 HAS3	Canis familiaris (dog)	G35674CY
Lewis blood group biosynthesis	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 2 Fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase L-Fucosyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A8I3MCT3 A0A8I3NB27 A0A8I3NB67 A0A8I3NFY5 A0A8I3NLH2 A0A8I3NR40 A0A8I3NRD0 A0A8I3P0Y9 A0A8I3PNT8 A0A8I3PQF7 A0A8I3Q8H7 A0A8I3RVW4 A0A8I3S1H8 Q5TJE8 Q659L1	B3GALT2 B3GALT4 B3GALT5 B4GALNT2 FUT10 FUT11 FUT2 FUT4 FUT5 FUT7 FUT9 ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Canis familiaris (dog)	G39211DH G81971FM G83633HB G90387AM G98173LG
Ficolins bind to repetitive carbohydrate structures on the target cell surface	MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein	A0A8I3MRI0 A0A8I3NLF4 A0A8I3PG15	FCN2 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
Initial triggering of complement	C4a anaphylatoxin Collectin subfamily member 10 Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MKD7 A0A8I3MRI0 A0A8I3NH95 A0A8I3NLF4 A0A8I3NQQ5 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PG15 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RST0 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7	C1QA C1QB C1QC C1R C1S C2 COLEC10 FCN2 LOC481722 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
Lectin pathway of complement activation	Collectin subfamily member 10 MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein	A0A8I3MRI0 A0A8I3NLF4 A0A8I3PG15 A0A8I3RST0	COLEC10 FCN2 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
Antimicrobial peptides	BPI fold containing family A member 2 BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold containing family B member 6 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein Cathelicidin Cathepsin G Chromogranin-A Elastase, neutrophil expressed Liver-expressed antimicrobial peptide 2 Lysozyme C, spleen isozyme Peptidase inhibitor 3 Peptidoglycan recognition protein 2 Peptidoglycan-recognition protein Rerating islet-derived 3 alpha Saposin B-type domain-containing protein trypsin	A0A5F4D5H8 A0A8I3MTX9 A0A8I3NJP0 A0A8I3NK04 A0A8I3NUZ6 A0A8I3PD99 A0A8I3PIK6 A0A8I3PIZ8 A0A8I3PJC6 A0A8I3PJT2 A0A8I3PMA8 A0A8I3PU85 A0A8I3S3D7 A0A8I3S705 D3DMB4 F1PZP0 P81709 Q6TN20 Q8MJD1	BPI BPIFA1 BPIFA2 BPIFB1 BPIFB2 BPIFB4 BPIFB6 CAMP CHGA CTSG ELA2 ELANE GNLY LEAP2 LOC100687463 PGLYRP1 PGLYRP2 PI3 PRSS2 REG3A	Canis familiaris (dog)	G49108TO
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 2 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET	A0A8I3MIM0 A0A8I3MPM4 A0A8I3MZL3 A0A8I3N687 A0A8I3NFN9 A0A8I3NRK7 A0A8I3NSG2 A0A8I3NZW4 A0A8I3PA80 A0A8I3PDC9 A0A8I3PMW4 A0A8I3PU75 A0A8I3PXQ6 A0A8I3Q329 A0A8I3RZH1 A0A8I3S7C1 A0A8I3SAG0 E2RRP8 Q5U9D0	FGF21 FGF8C MFSD4B SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Canis familiaris (dog)	G58161NS G70323CJ

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