GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **268** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Cargo concentration in the ER	Alpha 1 antitrypsin Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein Prolactin regulatory element-binding protein Protein cornichon homolog 2 Protein transport protein SEC23 SEC22 homolog B, vesicle trafficking protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Syntaxin 5 Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Vesicular integral-membrane protein VIP36 cathepsin X	A0A8I3MAV2 A0A8I3MLH1 A0A8I3MT80 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3N2I9 A0A8I3N5W4 A0A8I3N796 A0A8I3N9V0 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NYM5 A0A8I3NZH7 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PEN5 A0A8I3PQR9 A0A8I3PTW0 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RU45 A0A8I3RWZ7 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 P49256	AREG CD59 CNIH1 CNIH2 CNIH3 CTSC CTSZ F5 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 MIA2 PREB SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 TGFA TMED10 TMED2	Canis familiaris (dog)
Cargo recognition for clathrin-mediated endocytosis	AP complex subunit beta AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Adaptin ear-binding coat-associated protein 1 Apolipoprotein B ArfGAP with FG repeats 1 Arginine vasopressin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 8 COP9 signalosome subunit 5 COP9 signalosome subunit 7A COP9 signalosome subunit 7B Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein Clathrin heavy chain Clathrin heavy chain Clathrin light chain Clathrin light chain Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Frizzled-4 G protein pathway suppressor 1 G protein-coupled receptor kinase G protein-coupled receptor kinase Growth factor receptor bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Low-density lipoprotein receptor Mannose-6-phosphate receptor, cation dependent Muscarinic acetylcholine receptor NEDD8 Phosphatidylinositol binding clathrin assembly protein Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein Wnt RALBP1 associated Eps domain containing 1 RALBP1 associated Eps domain containing 2 Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin Synaptotagmin T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Torsin Torsin Trans-golgi network protein 2 Type-1 angiotensin II receptor Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vasopressin V2 receptor Vesicle associated membrane protein 4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	A0A8I3MAW6 A0A8I3MBG9 A0A8I3MBU4 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ91 A0A8I3MMN5 A0A8I3MQ56 A0A8I3MT64 A0A8I3MT80 A0A8I3MZG1 A0A8I3MZL3 A0A8I3N0H9 A0A8I3N1F4 A0A8I3N2C0 A0A8I3N2E5 A0A8I3N2P0 A0A8I3N399 A0A8I3N7P9 A0A8I3N8L8 A0A8I3N8T5 A0A8I3N970 A0A8I3NCI2 A0A8I3ND55 A0A8I3NE91 A0A8I3NF22 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NH32 A0A8I3NHL8 A0A8I3NHV2 A0A8I3NIR2 A0A8I3NKR3 A0A8I3NLC1 A0A8I3NPI2 A0A8I3NRM5 A0A8I3NS16 A0A8I3NTR3 A0A8I3NXQ1 A0A8I3NZX3 A0A8I3P087 A0A8I3P562 A0A8I3P6R3 A0A8I3P953 A0A8I3P9Q7 A0A8I3PCP2 A0A8I3PE10 A0A8I3PFJ2 A0A8I3PGA9 A0A8I3PGB9 A0A8I3PI71 A0A8I3PK82 A0A8I3PKW5 A0A8I3PMU1 A0A8I3PMU8 A0A8I3PP11 A0A8I3PPD9 A0A8I3PQE6 A0A8I3PRS1 A0A8I3PSX7 A0A8I3PT69 A0A8I3PV70 A0A8I3PVK3 A0A8I3PVM0 A0A8I3PWA8 A0A8I3Q314 A0A8I3Q374 A0A8I3Q3J5 A0A8I3Q545 A0A8I3Q5C2 A0A8I3Q5L9 A0A8I3QYD0 A0A8I3QZA5 A0A8I3RP69 A0A8I3RPS3 A0A8I3RR45 A0A8I3RTD0 A0A8I3RU23 A0A8I3RUS6 A0A8I3RV18 A0A8I3RV68 A0A8I3RYJ5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S1H6 A0A8I3S360 A0A8I3S4D1 A0A8I3S565 A0A8I3S6J8 A0A8I3S7E5 A0A8I3S9K7 A0A8I3SAF2 A0A8I3SBB3 B1H0W0 F1PHV6 P33705 P63050 Q5DUB3 Q5U820	AAK1 ABCC7 ADRB2 AGFG1 AGTR1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARRB1 ARRB2 AVP AVPR2 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CI-MPR/IGF2R CLTA CLTB CLTC CLTCL1 COPS2 COPS3 COPS5 COPS6 COPS7A COPS7B COPS8 DAB2 DVL2 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FZD4 GPS1 GRB2 GRK2 GRK3 HBEGF HGS IGF2R IL7R ITSN2 KIAA0319 LDLR LDLRAP1 LOC102156511 LOC119867035 LRP2 M6PR NECAP1 NECAP2 NEDD8 PICALM REPS2 RPS27A SCARB2 SH3GL1 SH3GL2 SH3KBP1 SLC18A3 SLC2A8 SNAP91 STAM STAM2 STON1 STON2 SYT1 SYT11 SYT2 SYT8 TACR1 TGFA TGOLN2 TOR1A TOR1B UBA52 UBB UBC UBCEP2 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 WNT5A	Canis familiaris (dog)
Cell surface interactions at the vascular wall	Apolipoprotein B CD2 molecule CD244 molecule CD44 antigen CD58 molecule CD74 molecule CD84 molecule CEA cell adhesion molecule 1 CEA cell adhesion molecule 20 CXADR Ig-like cell adhesion molecule E-selectin Endothelial cell adhesion molecule Epithelial cell adhesion molecule Fc alpha and mu receptor Fibronectin Glypican-1 Golgi apparatus protein 1 Growth arrest specific 6 High affinity immunoglobulin epsilon receptor subunit gamma Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Integrin beta Integrin beta Integrin subunit alpha 4 Integrin subunit alpha 5 Integrin subunit alpha D Integrin subunit alpha L Integrin subunit alpha M Joining chain of multimeric IgA and IgM Junction adhesion molecule like Junctional adhesion molecule 3 Junctional adhesion molecule A L-selectin Leukocyte surface antigen CD47 Macrophage migration inhibitory factor Oxidized low-density lipoprotein receptor 1 Platelet and endothelial cell adhesion molecule 1 Protein C receptor Prothrombin Selectin P ligand Selectin P Sialophorin Syndecan 4 Syndecan Syndecan Thrombomodulin Transforming growth factor beta Triggering receptor expressed on myeloid cells 1 Tyrosine-protein kinase Tyrosine-protein kinase UPAR/Ly6 domain-containing protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitamin K-dependent protein C Vitamin K-dependent protein S receptor protein-tyrosine kinase	A0A8I3MB16 A0A8I3MEX4 A0A8I3MFB3 A0A8I3MHM2 A0A8I3MHY1 A0A8I3MJX4 A0A8I3MMP8 A0A8I3MNI1 A0A8I3MNS0 A0A8I3MQ65 A0A8I3N050 A0A8I3N060 A0A8I3N3H1 A0A8I3N448 A0A8I3NG24 A0A8I3NKZ7 A0A8I3NQ82 A0A8I3NRC4 A0A8I3NS51 A0A8I3NUR7 A0A8I3NV00 A0A8I3NVW7 A0A8I3NWG4 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3T7 A0A8I3P3X1 A0A8I3P4F5 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P760 A0A8I3P941 A0A8I3PCF8 A0A8I3PCH7 A0A8I3PD67 A0A8I3PDU9 A0A8I3PED8 A0A8I3PIX4 A0A8I3PL11 A0A8I3PNK7 A0A8I3PQA6 A0A8I3PRY8 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PUT1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWC1 A0A8I3PWK4 A0A8I3PWS3 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PXS2 A0A8I3PYF1 A0A8I3Q092 A0A8I3Q1K1 A0A8I3Q4U0 A0A8I3Q5B7 A0A8I3Q5E2 A0A8I3Q5Y3 A0A8I3Q8L7 A0A8I3QAV2 A0A8I3QAV8 A0A8I3QC57 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QM62 A0A8I3QSK6 A0A8I3QX83 A0A8I3RQK1 A0A8I3RVF3 A0A8I3RW25 A0A8I3RWV8 A0A8I3S0A6 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S2B2 A0A8I3S2M3 A0A8I3S4D1 A0A8I3S5W6 A0A8I3S6H5 A0A8I3S6W0 A0A8I3S8N4 A0A8I3S934 A0A8I3S9C3 A0A8I3SA76 A0A8I3SAS3 A0A8I3SAS7 Q28278	APOB B9D2 CD177 CD2 CD244 CD44 CD47 CD48 CD58 CD74 CD84 CEACAM1 CEACAM20 CXADR EPCAM ESAM F11R F2 FCAMR FCER1G FN1 FYN GAS6 GLG1 GP6 GPC1 ITGA4 ITGA5 ITGAD ITGAL ITGAM ITGB1 ITGB2 JAM3 JAML JCHAIN LOC119867047 LOC119868972 LYN MERTK MIF OLR1 PECAM1 PROC PROCR PROS1 SDC1 SDC3 SDC4 SELE SELL SELP SELPLG SIRPA SPN THBD TREM1	Canis familiaris (dog)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 2 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET	A0A8I3MIM0 A0A8I3MPM4 A0A8I3MZL3 A0A8I3N687 A0A8I3NFN9 A0A8I3NRK7 A0A8I3NSG2 A0A8I3NZW4 A0A8I3PA80 A0A8I3PDC9 A0A8I3PMW4 A0A8I3PU75 A0A8I3PXQ6 A0A8I3Q329 A0A8I3RZH1 A0A8I3S7C1 A0A8I3SAG0 E2RRP8 Q5U9D0	FGF21 FGF8C MFSD4B SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Canis familiaris (dog)	G58161NS G70323CJ
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 7 Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Neurocan Sulfotransferase Versican core protein	A0A8I3MD46 A0A8I3MZ05 A0A8I3N108 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NAW4 A0A8I3NGD4 A0A8I3NHS7 A0A8I3NUF9 A0A8I3NUH2 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3Q1Q4 A0A8I3Q2X9 A0A8I3Q6I3 A0A8I3RX33 E2RLE9 Q29393	BCAN BGN CHPF CHPF2 CHST11 CHST12 CHST13 CHST3 CHST7 CHST9 CHSY1 CHSY3 CSGALNACT1 CSGALNACT2 CSPG4 CSPG5 DCN DCN1C NCAN VCAN	Canis familiaris (dog)
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1 Histone deacetylase 6	A0A8I3MV46 A0A8I3Q5U6	ATAT1 HDAC6 MEC17	Canis familiaris (dog)
Class A/1 (Rhodopsin-like receptors)	Cannabinod receptor Chemerin-like receptor 1 G protein-coupled receptor 183 G protein-coupled receptor 35 G protein-coupled receptor 55 G protein-coupled receptor 68 G-protein coupled bile acid receptor 1 Melatonin receptor 1B Melatonin receptor type 1A N-arachidonyl glycine receptor Oxoglutarate receptor 1 Platelet-activating factor receptor Succinate receptor 1 Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3NKP7 A0A8I3P831 A0A8I3P8G7 A0A8I3PBK9 A0A8I3PDW8 A0A8I3PE74 A0A8I3PH14 A0A8I3PIK0 A0A8I3PZA6 A0A8I3Q1X3 A0A8I3Q2D1 A0A8I3QYW7 A0A8I3RTK7 A0A8I3RY80 A0A8I3S3R7 E2RKA3	CB2 CMKLR1 CNR2 GPBAR1 GPR132 GPR18 GPR183 GPR35 GPR39 GPR55 GPR68 HCAR2 MTNR1A MTNR1B OXGR1 PTAFR SUCNR1	Canis familiaris (dog)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Corticoliberin Corticotropin releasing hormone receptor 2 Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Sushi domain-containing protein Tuberoinfundibular peptide of 39 residues Uncharacterized protein Uncharacterized protein Urocortin	A0A8I3MZB5 A0A8I3P6W0 A0A8I3P7R9 A0A8I3PCJ2 A0A8I3PCP1 A0A8I3PHA9 A0A8I3PPK6 A0A8I3PPW2 A0A8I3RQ73 A0A8I3RSJ3 A0A8I3RVU2 A0A8I3RXL4 P52211 P52212 Q2Q423 Q9TU31	ADGRE1 ADGRE3 ADGRE5 CD55 CRH CRHBP CRHR1 CRHR2 LOC484897 PTH PTH1 PTH1R PTH2 PTH2R PTHLH PTHR1 UCN UCN3	Canis familiaris (dog)
Clathrin-mediated endocytosis	ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 6 AP complex subunit beta AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Amphiphysin Apolipoprotein B ArfGAP with FG repeats 1 Arginine vasopressin Arp2/3 complex 34 kDa subunit Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Bridging integrator 1 Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein Clathrin heavy chain Clathrin heavy chain Clathrin light chain Clathrin light chain Cyclin G associated kinase Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 DnaJ heat shock protein family (Hsp40) member C6 E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Formin binding protein 1 Formin-binding protein 1-like Frizzled-4 GTPase activating protein and VPS9 domains 1 Growth factor receptor bound protein 2 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin interacting protein 1 related Huntingtin interacting protein 1 Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Low-density lipoprotein receptor Mannose-6-phosphate receptor, cation dependent Muscarinic acetylcholine receptor Phosphatidylinositol binding clathrin assembly protein Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein Wnt Protein kinase C and casein kinase substrate in neurons 1 Protein kinase C and casein kinase substrate in neurons 2 Protein kinase C and casein kinase substrate in neurons 3 Queuine tRNA-ribosyltransferase catalytic subunit 1 RALBP1 associated Eps domain containing 1 RALBP1 associated Eps domain containing 2 Ras-related protein Rab-5A Ras-related protein Rab-5C Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Sorting nexin 18 Sorting nexin 9 Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin Synaptotagmin T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Thyroid hormone receptor interactor 10 Trans-golgi network protein 2 Type-1 angiotensin II receptor Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vasopressin V2 receptor Vesicle associated membrane protein 4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 WASP like actin nucleation promoting factor dynamin GTPase dynamin GTPase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase small monomeric GTPase	A0A8I3MAW6 A0A8I3MBG9 A0A8I3MBU4 A0A8I3MFQ5 A0A8I3MFY1 A0A8I3MIP1 A0A8I3MJ11 A0A8I3MJ91 A0A8I3MMN5 A0A8I3MNR2 A0A8I3MPK0 A0A8I3MPX3 A0A8I3MQ56 A0A8I3MQX2 A0A8I3MT64 A0A8I3MT80 A0A8I3MZG1 A0A8I3MZL3 A0A8I3N0H9 A0A8I3N156 A0A8I3N1F4 A0A8I3N1Q4 A0A8I3N1W7 A0A8I3N2E5 A0A8I3N2P0 A0A8I3N6A2 A0A8I3N7P9 A0A8I3N8J8 A0A8I3N8L8 A0A8I3N8T5 A0A8I3N970 A0A8I3NCI2 A0A8I3NCU8 A0A8I3ND55 A0A8I3NE45 A0A8I3NEW9 A0A8I3NF22 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NH32 A0A8I3NHL8 A0A8I3NHV2 A0A8I3NIE0 A0A8I3NKR3 A0A8I3NLC1 A0A8I3NNW3 A0A8I3NPI2 A0A8I3NRM5 A0A8I3NS16 A0A8I3NTR3 A0A8I3NW16 A0A8I3NXQ1 A0A8I3NZC2 A0A8I3NZX3 A0A8I3P087 A0A8I3P562 A0A8I3P6R3 A0A8I3P953 A0A8I3P9Q7 A0A8I3PFJ2 A0A8I3PFM7 A0A8I3PGA9 A0A8I3PGB9 A0A8I3PGP9 A0A8I3PJG5 A0A8I3PK72 A0A8I3PKW5 A0A8I3PLP7 A0A8I3PMU1 A0A8I3PMU8 A0A8I3PP11 A0A8I3PPD9 A0A8I3PPQ5 A0A8I3PQE6 A0A8I3PSX7 A0A8I3PT69 A0A8I3PWA8 A0A8I3PZW5 A0A8I3Q052 A0A8I3Q065 A0A8I3Q2I4 A0A8I3Q314 A0A8I3Q374 A0A8I3Q3J5 A0A8I3Q545 A0A8I3Q5C2 A0A8I3Q5L9 A0A8I3QYD0 A0A8I3QZA5 A0A8I3RP69 A0A8I3RPS3 A0A8I3RR45 A0A8I3RR73 A0A8I3RTD0 A0A8I3RU23 A0A8I3RUF5 A0A8I3RUS6 A0A8I3RV18 A0A8I3RV68 A0A8I3RYJ5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S1H6 A0A8I3S1K9 A0A8I3S1V5 A0A8I3S360 A0A8I3S4D1 A0A8I3S565 A0A8I3S6J8 A0A8I3S7E5 A0A8I3S7Q4 A0A8I3S7X1 A0A8I3S9K7 A0A8I3SAF2 A0A8I3SAR3 B1H0W0 F1PHV6 P18066 P33705 P51147 P63050 Q5DUB3 Q5U820	AAK1 ABCC7 ACTR2 ACTR3 ADRB2 AGFG1 AGTR1 AMPH AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARF6 ARFGAP1 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARRB1 ARRB2 AVP AVPR2 BIN1 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CI-MPR/IGF2R CLTA CLTB CLTC CLTCL1 DAB2 DNAJC6 DNM1 DNM2 DNM3 DVL2 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FNBP1 FNBP1L FZD4 GAK GAPVD1 GRB2 HBEGF HGS HIP1 HIP1R IGF2R IL7R ITSN2 KIAA0319 LDLR LDLRAP1 LOC102156511 LOC119867035 LOC607182 LRP2 M6PR NECAP1 NECAP2 OCRL PACSIN1 PACSIN2 PACSIN3 PICALM PIK3C2A PIP5K1C QTRT1 RAB5A RAB5B RAB5C REPS2 RPS27A SCARB2 SH3GL1 SH3GL2 SH3KBP1 SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 STAM STAM2 STON1 STON2 SYNJ1 SYNJ2 SYT1 SYT11 SYT2 SYT8 TACR1 TGFA TGOLN2 TRIP10 UBA52 UBB UBC UBCEP2 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 WASL WNT5A	Canis familiaris (dog)
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Collagen type XII alpha 1 chain Collagen type XIII alpha 1 chain Collagen type XIX alpha 1 chain Collagen type XV alpha 1 chain Collagen type XVIII alpha 1 chain Collagen type XXV alpha 1 chain Collagen type XXVI alpha 1 chain Collagenase 3 Matrix metallopeptidase 12 Matrix metallopeptidase 15 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Stromelysin-1 Transmembrane serine protease 6 furin interstitial collagenase trypsin	A0A8I3MCQ8 A0A8I3MGS0 A0A8I3MJI6 A0A8I3MND9 A0A8I3MSY3 A0A8I3MWG8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N1T9 A0A8I3N1V6 A0A8I3N4V8 A0A8I3NL35 A0A8I3P478 A0A8I3PD99 A0A8I3PHE2 A0A8I3QKG6 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3RVF8 A0A8I3S0M3 Q4LAL9 Q6Y4Q5	COL12A1 COL13A1 COL15A1 COL18A1 COL19A1 COL25A1 COL26A1 CTSB CTSD FURIN MMP1 MMP12 MMP13 MMP14 MMP15 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 PHYKPL PRSS2 TMPRSS6	Canis familiaris (dog)
Common Pathway of Fibrin Clot Formation	Antithrombin-III Coagulation factor V Coagulation factor X Coagulation factor XIII A chain Coagulation factor XIII B chain Protein C receptor Proteinase-activated receptor 1 Prothrombin Serpin domain-containing protein Serpin family A member 5 Serpin family D member 1 Thrombomodulin Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A8I3MGM0 A0A8I3MLH1 A0A8I3MQ40 A0A8I3NE44 A0A8I3NHZ1 A0A8I3P760 A0A8I3P7K7 A0A8I3PPY1 A0A8I3PQV5 A0A8I3PUT1 A0A8I3Q092 A0A8I3QAV8 A0A8I3S1X8 Q28278	F10 F13A1 F13B F2 F2R F5 PROC PROCR PROS1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 THBD	Canis familiaris (dog)
Costimulation by the CD28 family	B and T lymphocyte associated Growth factor receptor bound protein 2 Ig-like domain-containing protein Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 TNF receptor superfamily member 14 Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3P405 A0A8I3P519 A0A8I3P6Z0 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWC6 A0A8I3Q857 A0A8I3S3N2 Q7YR73	AILIM BTLA GRB2 ICOS ICOSLG LOC100856339 PIK3CA PIK3R1 PIK3R2 PTPN11 PTPN6 TNFRSF14	Canis familiaris (dog)
Creatine metabolism	Creatine kinase B-type Creatine kinase M-type Creatine kinase S-type, mitochondrial Creatine kinase U-type, mitochondrial Glycine amidinotransferase Sodium- and chloride-dependent betaine transporter Transporter Transporter Transporter guanidinoacetate N-methyltransferase	A0A8I3N7M6 A0A8I3NN25 A0A8I3PNS0 A0A8I3QPK3 A0A8I3RV00 A0A8I3S431 A0A8I3S958 P05123 P05124 P27799	CKB CKM CKMT2 GAMT GATM LOC478277 SLC6A11 SLC6A12 SLC6A7 SLC6A8	Canis familiaris (dog)
Cytoprotection by HMOX1	Albumin Biliverdin reductase A Cytochrome c oxidase assembly factor COX14 Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase copper chaperone COX11 Cytochrome c oxidase polypeptide VIa Cytochrome c oxidase polypeptide VIa Cytochrome c oxidase subunit 4 Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A2 like Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8 Cytochrome c oxidase subunit NDUFA4 Cytochrome c oxidase subunit Cytochrome c oxidase subunit Cytochrome c oxidase subunit Cytochrome c DNA helicase F-box-like/WD repeat-containing protein TBL1X Fatty acid-binding protein, liver Globin A2 Globin domain-containing protein Heme oxygenase 1 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Leucine rich pentatricopeptide repeat containing Mediator of RNA polymerase II transcription subunit 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 mitochondrial complex associated NDUFA4 mitochondrial complex associated Nuclear receptor coactivator 6 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR SIN3 transcription regulator family member A SIN3 transcription regulator family member B SURF1-like protein SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Synthesis of cytochrome C oxidase 1 Synthesis of cytochrome C oxidase 2 TBL1X/Y related 1 Translational activator of cytochrome c oxidase I Trimethylguanosine synthase heme oxygenase (biliverdin-producing) histone acetyltransferase	A0A1K0GGH0 A0A8I3MCD6 A0A8I3MH42 A0A8I3MJJ8 A0A8I3MM51 A0A8I3MRB3 A0A8I3MTJ4 A0A8I3MU45 A0A8I3MUD3 A0A8I3MWA1 A0A8I3MX58 A0A8I3MY68 A0A8I3MZU1 A0A8I3N1I8 A0A8I3N2D2 A0A8I3N2S3 A0A8I3N418 A0A8I3ND57 A0A8I3NDH4 A0A8I3NEL7 A0A8I3NF47 A0A8I3NIH7 A0A8I3NLZ5 A0A8I3NN37 A0A8I3NWB8 A0A8I3P0C7 A0A8I3P468 A0A8I3P4W9 A0A8I3P6P5 A0A8I3P8E0 A0A8I3P9C2 A0A8I3PCR3 A0A8I3PD11 A0A8I3PDU7 A0A8I3PKZ2 A0A8I3PNU0 A0A8I3PQX0 A0A8I3PRC4 A0A8I3PUL6 A0A8I3PWS0 A0A8I3PXU1 A0A8I3PYI4 A0A8I3Q3T3 A0A8I3Q6Z7 A0A8I3Q729 A0A8I3RW50 A0A8I3S1H9 A0A8I3S1Z7 A0A8I3S1Z9 A0A8I3S3K8 A0A8I3S5Q5 A0A8I3SCF2 A0A8I3SCU6 F1PKU9 P00011 Q6UR05	ABCC1 ALB BLVRA CARM1 CHD9 COX11 COX16 COX18 COX4I1 COX5A COX5B COX7A2L CREBBP CYC CYCS FABP1 GLNA2 GLNA3 HBQ1 HDAC3 HMOX1 HMOX2 LOC100682956 LOC100684983 LOC100688724 LOC119868178 LOC477508 LOC606860 LOC609402 LOC612644 LRPPRC MED1 MRP1 NCOA1 NCOA2 NCOA6 NCOR1 NCOR2 PPARA RXRA SCO1 SCO2 SIN3A SIN3B SMARCD3 SURF1 TACO1 TBL1X TBL1XR1 TGS1	Canis familiaris (dog)
DAP12 interactions	Beta-2-microglobulin C-type lectin domain-containing protein C-type lectin domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin subtype domain-containing protein Natural killer cells antigen CD94 Sialic acid binding Ig like lectin 15 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 1 Uncharacterized protein Uncharacterized protein	A0A8I3MDD5 A0A8I3MMC4 A0A8I3MNY2 A0A8I3MVN4 A0A8I3MYW9 A0A8I3NKZ7 A0A8I3NMD0 A0A8I3NVH5 A0A8I3PNS2 A0A8I3PWV8 A0A8I3PXH7 A0A8I3QBX8 A0A8I3S091 A0A8I3S0A6 A0A8I3S2M3 A0A8I3S2Y6 Q38HS3	B2M CD300E CD94 CLEC5A KLRD1 LOC119863908 LOC119866326 LOC119873404 LOC476396 LOC484343 SIGLEC15 SIRPA TREM1 TYROBP	Canis familiaris (dog)
DAP12 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Beta-2-microglobulin C-type lectin domain-containing protein C-type lectin domain-containing protein GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Immunoglobulin subtype domain-containing protein Lymphocyte cytosolic protein 2 NKG2-D type II integral membrane protein Natural killer cells antigen CD94 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 TYRO protein tyrosine kinase-binding protein Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3MDD5 A0A8I3MGV8 A0A8I3MMK3 A0A8I3N971 A0A8I3NAC6 A0A8I3NC73 A0A8I3NEZ8 A0A8I3NH46 A0A8I3NUU1 A0A8I3NVH5 A0A8I3NZG2 A0A8I3P3G0 A0A8I3P3X1 A0A8I3P6Q8 A0A8I3P7Z3 A0A8I3PNL2 A0A8I3PNS2 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PWV8 A0A8I3PXH7 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3S3N2 A0A8I3SCI7 P62999 Q38HS3	B2M BTK CD94 FYN GRAP2 GRB2 HRAS KLRD1 KLRK1 KRAS LAT LCK LCP2 LOC119863908 LOC119866326 NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PLCG2 RAC1 SHC1 SOS1 SYK TYROBP VAV2 VAV3	Canis familiaris (dog)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase domain 15 ADAM metallopeptidase domain 8 ADAM metallopeptidase with thrombospondin type 1 motif 5 Aggrecan core protein Alpha-2-macroglobulin Basigin Brevican core protein CD44 antigen Cadherin-1 Cadherin-1 Calpain 10 Calpain 11 Calpain 12 Calpain 13 Calpain 14 Calpain 15 Calpain 5 Calpain 6 Calpain 9 Calpain catalytic domain-containing protein Calpain catalytic domain-containing protein Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-3 Calpastatin Cathepsin G Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Elastase, neutrophil expressed HtrA serine peptidase 1 Kallikrein D Matrix metallopeptidase 11 Matrix metallopeptidase 12 Matrix metallopeptidase 19 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Nidogen 1 Opticin Procathepsin L Secreted phosphoprotein 1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Transmembrane serine protease 6 interstitial collagenase	A0A8I3MCQ8 A0A8I3MDF9 A0A8I3MEZ7 A0A8I3MGS0 A0A8I3MM49 A0A8I3MND9 A0A8I3MS95 A0A8I3MTX4 A0A8I3MUT8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N8Z0 A0A8I3NAW1 A0A8I3NBM1 A0A8I3NET5 A0A8I3NF92 A0A8I3NG54 A0A8I3NHT2 A0A8I3NK04 A0A8I3NLH7 A0A8I3NNE0 A0A8I3NQ99 A0A8I3P0M4 A0A8I3P0U1 A0A8I3P1W2 A0A8I3P478 A0A8I3P4K7 A0A8I3P533 A0A8I3P8U9 A0A8I3PAG9 A0A8I3PCF8 A0A8I3PED9 A0A8I3PJW4 A0A8I3PMD6 A0A8I3PRM5 A0A8I3PVS1 A0A8I3Q3A2 A0A8I3Q5H9 A0A8I3QPC2 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3S3W1 A0A8I3S676 A0A8I3S9F9 A0A8I3SBJ8 E2FGH7 F1PAA9 Q29393 Q6Y4Q5 Q8MJD1 Q9GL24	A2M ACAN ADAM10 ADAM15 ADAM8 ADAMTS4 ADAMTS5 BCAN BSG CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS1 CAST CD44 CDH1 CTSG CTSL CTSL1 CTSS DCN DCN1C ELA2 ELANE HTRA1 KLK7 KLND MMP1 MMP11 MMP12 MMP13 MMP14 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 NID1 OPTC SCUBE1 SCUBE3 SPP1 TMPRSS6	Canis familiaris (dog)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan sulfate epimerase like Dermatan sulfate epimerase Neurocan Uronyl 2-sulfotransferase Versican core protein	A0A8I3MK93 A0A8I3MZW8 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NUF9 A0A8I3NUZ7 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 Q29393	BCAN BGN CSPG4 CSPG5 DCN DCN1C DSE DSEL NCAN UST VCAN	Canis familiaris (dog)
Digestion	Alkaline phosphatase Guanylate cyclase activator 2B Guanylate cyclase Guanylin Pirin	A0A8I3N4X7 A0A8I3P3W4 A0A8I3PB32 A0A8I3PK10 A0A8I3QK41	ALPI GUCA2A GUCA2B GUCY2C PIR	Canis familiaris (dog)
Digestion of dietary carbohydrate	Alpha-amylase Lactase Maltase-glucoamylase Sucrase-isomaltase chitinase	A0A8I3MKS5 A0A8I3NDB4 A0A8I3P4Z5 A0A8I3QYQ3 J9PAL7	CHIA LCT LOC119879923 LOC119881526 MGAM SI	Canis familiaris (dog)	G58161NS G74621DY G93924TT G96370VA
Downstream TCR signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 BCL10 immune signaling adaptor Caspase recruitment domain family member 11 Cullin 1 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme F-box and WD repeat domain containing 11 Ig-like domain-containing protein IkappaB kinase Immunoglobulin V-set domain-containing protein Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein kinase C RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha variable 29/delta variable 5 T cell receptor associated transmembrane adaptor 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ82 A0A8I3MKK6 A0A8I3MKL4 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MNA4 A0A8I3MNI0 A0A8I3MQX7 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MV98 A0A8I3MZ69 A0A8I3N0P1 A0A8I3N165 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N7L6 A0A8I3N952 A0A8I3N971 A0A8I3N9G3 A0A8I3NAC6 A0A8I3NFB9 A0A8I3NH42 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NT57 A0A8I3NT75 A0A8I3NTK0 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NW81 A0A8I3NXK9 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4A1 A0A8I3P4Z1 A0A8I3P564 A0A8I3P6I7 A0A8I3P6M2 A0A8I3PAB8 A0A8I3PAP4 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PFI5 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PMA2 A0A8I3PR42 A0A8I3PWT3 A0A8I3PZT2 A0A8I3QV78 A0A8I3QYD0 A0A8I3RR14 A0A8I3RRK6 A0A8I3RRL7 A0A8I3RRR7 A0A8I3RT39 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S023 A0A8I3S1Z6 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S3N2 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P27597 P33705 P60483 P63050 Q5W412 Q5W416 Q6F3J0	BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CDC34 CHUK CUL1 DLA-DQA1 DLA-DRA FBXW11 HLA-DQB2 IKBKB IKBKG INPP5D LCK LOC100686569 LOC100687259 LOC119881719 LOC610717 MALT1 MAP3K7 MMAC1 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKCQ PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN RELA RIPK2 RPS27A SKP1 TAB2 TRAF6 TRAT1 TRAV29DV5 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2N	Canis familiaris (dog)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk BCAR1 scaffold protein, Cas family member CRK like proto-oncogene, adaptor protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B RAS p21 protein activator 1 Rap guanine nucleotide exchange factor 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N1K5 A0A8I3N488 A0A8I3N971 A0A8I3N974 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NGQ0 A0A8I3NID0 A0A8I3P5F5 A0A8I3PDZ1 A0A8I3PMT9 A0A8I3PN08 A0A8I3PSA1 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RV66 A0A8I3RVE7 A0A8I3RXB9 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S602 A0A8I3S8J3 A0A8I3SBF9 A0A8I3SCI7 Q6Q7I7	BCAR1 CRK CRKL GRB2 GRB7 HRAS KRAS NCK1 NCK2 NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PTPN11 RAPGEF1 RASA1 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6	Canis familiaris (dog)
Downstream signaling of activated FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PDH2 A0A8I3PJY6 A0A8I3RV97 A0A8I3SAY5 A0A8I3SCU1 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FLRT1 FLRT2 FLRT3 KL	Canis familiaris (dog)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	A0A8I3NGY1 Q867B7	HGF MET	Canis familiaris (dog)
ECM proteoglycans	Aggrecan core protein Agrin Biglycan Brevican core protein Cartilage oligomeric matrix protein Collagen type IX alpha 1 chain Collagen type IX alpha 2 Collagen type IX alpha 3 chain Decorin Dentin matrix acidic phosphoprotein 1 Dentin sialophosphoprotein Fibronectin type-III domain-containing protein Hyaluronan and proteoglycan link protein 1 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 7 Integrin subunit alpha 8 Integrin subunit alpha 9 Integrin subunit alpha D Integrin subunit alpha V Matrilin 1 Matrilin 3 Matrilin 4 Neurocan Plasminogen activator inhibitor 1 SPARC Tenascin C Tenascin R Versican core protein Vitronectin	A0A8I3MC22 A0A8I3MDS4 A0A8I3MMP8 A0A8I3MS95 A0A8I3MWF4 A0A8I3N567 A0A8I3N600 A0A8I3N8Z0 A0A8I3NBB5 A0A8I3NFV4 A0A8I3NG24 A0A8I3NJU0 A0A8I3NL86 A0A8I3NUF9 A0A8I3P2A0 A0A8I3P4U9 A0A8I3P613 A0A8I3P787 A0A8I3P874 A0A8I3PAS0 A0A8I3PHY6 A0A8I3PLC3 A0A8I3PMU9 A0A8I3PZR7 A0A8I3QCJ7 A0A8I3RVA0 A0A8I3RVR5 A0A8I3RYZ7 A0A8I3S0I3 A0A8I3S0V6 A0A8I3S0V9 A0A8I3S700 E2DP67 Q29393	ACAN AGRN BCAN BGN COL9A1 COL9A2 COL9A3 COMP DCN DCN1C DMP1 DSPP HAPLN1 ITGA2 ITGA2B ITGA7 ITGA8 ITGA9 ITGAD ITGAV ITGB1 ITGB3 ITGB5 ITGB6 MATN1 MATN3 MATN4 NCAN SEBOX SERPINE1 SPARC TNC TNR VCAN	Canis familiaris (dog)

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