GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Multifunctional fusion protein Ras-related protein Rab-3 Regulating synaptic membrane exocytosis 1 Synaptotagmin Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	A0A8I3ME77 A0A8I3MLF8 A0A8I3MQ89 A0A8I3N2E5 A0A8I3N5Z9 A0A8I3NNW3 A0A8I3P737 A0A8I3PDP4 A0A8I3PNE3 A0A8I3Q823 A0A8I3S6J8 A0PA85 Q4PRC2	CPLX1 DNAJC5 GAD1 GAD2 GAD65 GAD67 LOC607182 RAB3A RIMS1 SLC32A1 SNAP25 STX1A STXBP1 SYT1 VAMP2	Canis familiaris (dog)
MET activates RAP1 and RAC1	Adapter molecule crk CRK like proto-oncogene, adaptor protein Dedicator of cytokinesis 7 GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 small monomeric GTPase small monomeric GTPase	A0A8I3NGQ0 A0A8I3NGY1 A0A8I3NH46 A0A8I3NUL4 A0A8I3NXI8 A0A8I3P5F5 A0A8I3PN08 A0A8I3PT69 A0A8I3RSH7 A0A8I3RUF3 P62999 Q867B7	CRK CRKL DOCK7 GAB1 GRB2 HGF MET RAC1 RAP1A RAP1B RAPGEF1	Canis familiaris (dog)
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor bound protein 2 Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MVN6 A0A8I3N971 A0A8I3N9M7 A0A8I3NFE2 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PAP4 A0A8I3PBB4 A0A8I3PT69 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q525 A0A8I3RRY0 A0A8I3RS40 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S4Z2 P48749 Q29416 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB GAB2 GRB2 IL2 IL2RA IL2RB IL3 IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN6 SHC1 SHIP2 SOS1	Canis familiaris (dog)
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Vav guanine nucleotide exchange factor 1 cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3N974 A0A8I3NA65 A0A8I3NBM3 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PBB4 A0A8I3PMT9 A0A8I3PRW9 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q4Y8 A0A8I3Q525 A0A8I3RVE7 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3N2 P48749 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB IL3 IL5 IL5RA JAK2 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ	Canis familiaris (dog)
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin, lysosomal cystine transporter Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A8I3N947 A0A8I3NY92 A0A8I3P1B2 A0A8I3P4E1 A0A8I3PQ76 A0A8I3Q823 A0A8I3RSG2 Q9N280	CTNS GLAST SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1	Canis familiaris (dog)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Procathepsin L Serpin family B member 13	A0A8I3MMH2 Q9GL24	CTSL CTSL1 SERPINB13	Canis familiaris (dog)
Synthesis of bile acids and bile salts	Cytochrome P450 family 7 subfamily A member 1 Cytochrome P450 family 7 subfamily B member 1 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Retinoic acid receptor RXR	A0A8I3N2S7 A0A8I3NA48 A0A8I3NIH7 A0A8I3NPK5 A0A8I3NS93 A0A8I3P033 A0A8I3P4G5 A0A8I3PNT4 A0A8I3PRC4 A0A8I3PYI4 A0A8I3S236 A0A8I3S5H8 A0A8I3SAZ3	CYP7A1 CYP7B1 NCOA1 NCOA2 NR1H4 OSBP OSBPL1A OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RXRA	Canis familiaris (dog)
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 Slit guidance ligand 2	A0A8I3NQC4 Q9TSZ6	DAG1 SLIT2	Canis familiaris (dog)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A8I3MQ54 A0A8I3MSC7 A0A8I3NN17 A0A8I3P237 A0A8I3P626 A0A8I3Q4Y1 A0A8I3Q7C5 A0A8I3RVI9 A0A8I3RZI7 A0A8I3S1Y7 A0A8I3SAK1	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT	Canis familiaris (dog)	G31080DL
Arachidonic acid metabolism	Acyltransferase Phospholipase A2 fatty acid amide hydrolase	A0A8I3MZB9 A0A8I3P542 A0A8I3Q562	DGAT2L6 FAAH PLA2G4A	Canis familiaris (dog)
Synaptic adhesion-like molecules	Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 Flotillin Flotillin Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor Leucine rich repeat and fibronectin type III domain containing 1 Leucine rich repeat and fibronectin type III domain containing 2 Leucine rich repeat and fibronectin type III domain containing 4 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Receptor-type tyrosine-protein phosphatase F Reticulon protein-tyrosine-phosphatase	A0A8I3MHF6 A0A8I3MLF1 A0A8I3MYK4 A0A8I3N069 A0A8I3N2F7 A0A8I3N7W4 A0A8I3NEU9 A0A8I3NRD6 A0A8I3NUJ0 A0A8I3NVY0 A0A8I3NZA0 A0A8I3P9B8 A0A8I3PJ11 A0A8I3PXY0 A0A8I3QNS7 A0A8I3RRH4 A0A8I3RS83 A0A8I3S101 Q5R1P0 Q5R1P3	DLG1 DLG3 DLG4 FLOT1 FLOT2 GRIA1 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D LRFN1 LRFN2 LRFN3 LRFN4 NMDAR1 PTPRD PTPRF RTN3	Canis familiaris (dog)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Free fatty acid receptor 4 G protein subunit alpha transducin 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Glucagon Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Leptin	A0A8I3MH22 A0A8I3P5C5 A0A8I3PJF2 A0A8I3PQY2 A0A8I3Q958 A0A8I3QXE0 A0A8I3QZL6 A0A8I3RQW9 A0A8I3S964 P62872 P79147	DPP4 FFAR1 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP LEP	Canis familiaris (dog)	G58161NS
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4	Canis familiaris (dog)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Toll-like receptor 9 Toll-like receptor 9 Uncharacterized protein non-specific serine/threonine protein kinase	A0A8I3MWD3 A0A8I3PJ50 A0A8I3PZW3 A0A8I3Q7B4 A0A8I3QFN1 Q5I2M8	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Canis familiaris (dog)
EPH-Ephrin signaling	EPH receptor A10 EPH receptor B6 EPH-related receptor tyrosine kinase ligand 7 Ephrin A2 Ephrin A3 Ephrin A4 Ephrin B3 Ephrin type-B receptor 3 Ephrin-A1 Ephrin-B2 Uncharacterized protein receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A8I3MB23 A0A8I3MBN5 A0A8I3MD88 A0A8I3MVS4 A0A8I3N250 A0A8I3NEL5 A0A8I3NQ24 A0A8I3NR10 A0A8I3NS68 A0A8I3NYD1 A0A8I3PTE3 A0A8I3PZY2 A0A8I3Q5U0 A0A8I3QB00 A0A8I3RP21 A0A8I3RVX4 A0A8I3RZP3 A0A8I3S0G7 A0A8I3SCP8 B0LDS6	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB2 EPHB3 EPHB4 EPHB6 efnB2	Canis familiaris (dog)
EGFR Transactivation by Gastrin	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1 small monomeric GTPase	A0A8I3PSP7 A0A8I3PT69 A0A8I3PUQ8 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RPS3 A0A8I3RYJ5 A0A8I3S3D9 Q6Y4Q5	EGFR GRB2 HBEGF HRAS KRAS MMP3 NRAS PRKCA SOS1	Canis familiaris (dog)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor	A0A8I3MAV6 A0A8I3RRT3	ESR1 ESR2	Canis familiaris (dog)
Common Pathway of Fibrin Clot Formation	Antithrombin-III Coagulation factor V Coagulation factor X Coagulation factor XIII A chain Coagulation factor XIII B chain Protein C receptor Proteinase-activated receptor 1 Prothrombin Serpin domain-containing protein Serpin family A member 5 Serpin family D member 1 Thrombomodulin Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A8I3MGM0 A0A8I3MLH1 A0A8I3MQ40 A0A8I3NE44 A0A8I3NHZ1 A0A8I3P760 A0A8I3P7K7 A0A8I3PPY1 A0A8I3PQV5 A0A8I3PUT1 A0A8I3Q092 A0A8I3QAV8 A0A8I3S1X8 Q28278	F10 F13A1 F13B F2 F2R F5 PROC PROCR PROS1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 THBD	Canis familiaris (dog)
GP1b-IX-V activation signalling	14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase von Willebrand factor von Willebrand factor	A0A8I3PZA0 A0A8I3Q4Y8 A0A8I3SBF9 A0A8I3SCK0 Q28295	F8VWF RAF1 SRC VWF YWHAZ	Canis familiaris (dog)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein	A0A8I3MRI0 A0A8I3NLF4 A0A8I3PG15	FCN2 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
GDP-fucose biosynthesis	Fucose kinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A8I3MTB3 A0A8I3NTS0 A0A8I3NVI9 A0A8I3PWT5 A0A8I3Q1E5 A0A8I3RTZ0	FCSK FPGT FUOM GFUS GMDS SLC35C1	Canis familiaris (dog)	G85196CF G96881BQ
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Toll-like receptor 9 Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MWD3 A0A8I3N971 A0A8I3N9M7 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWT3 A0A8I3Q7B4 A0A8I3QFN1 A0A8I3RTN7 A0A8I3S0I1 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0 Q5I2M8	FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 GAB1 GAB2 GRB2 IRS1 IRS2 KGF KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9	Canis familiaris (dog)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NM39 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 FRS3 GRB2 HRAS KGF KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
PI-3K cascade:FGFR2	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3N971 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 GAB1 GRB2 KGF PIK3CA PIK3R1 PTPN11	Canis familiaris (dog)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 GRB2 HRAS KGF KRAS NRAS SHC1 SOS1	Canis familiaris (dog)

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