GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 KGF PLCG1	Canis familiaris (dog)
Downstream signaling of activated FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PDH2 A0A8I3PJY6 A0A8I3RV97 A0A8I3SAY5 A0A8I3SCU1 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FLRT1 FLRT2 FLRT3 KL	Canis familiaris (dog)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NM39 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FRS2 FRS3 GRB2 HRAS KL KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
PI-3K cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MP09 A0A8I3N971 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FRS2 GAB1 GRB2 KL PIK3CA PIK3R1 PTPN11	Canis familiaris (dog)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 GRB2 HRAS KL KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 KL PLCG1	Canis familiaris (dog)
FGFR2b ligand binding and activation	Fibroblast growth factor 7 Fibroblast growth factor binding protein 1 Fibroblast growth factor binding protein 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein	A0A8I3MH10 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3Q445 P79150	FGF1 FGF10 FGF22 FGF3 FGF7 FGFBP1 FGFBP3 FGFR2 KGF	Canis familiaris (dog)
FGFR1b ligand binding and activation	Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GIPC PDZ domain containing family member 1 Multifunctional fusion protein Transforming growth factor beta receptor 3	A0A8I3MP09 A0A8I3NHF3 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NV07 A0A8I3NYK3 A0A8I3NZI6 A0A8I3PDK4	FGF1 FGF10 FGF22 FGF3 FGFR1 GIPC1 TGFBR3	Canis familiaris (dog)
FGFR2c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NTD6 A0A8I3NV07 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2	Canis familiaris (dog)
FRS-mediated FGFR3 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NM39 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 FRS2 FRS3 GRB2 HRAS KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
PI-3K cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3N971 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 FRS2 GAB1 GRB2 PIK3CA PIK3R1 PTPN11	Canis familiaris (dog)
FGFR3c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Polypeptide N-acetylgalactosaminyltransferase Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P0X5 A0A8I3PJY6 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GALNT3	Canis familiaris (dog)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GRB2 HRAS KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 PLCG1	Canis familiaris (dog)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty related EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2 Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MXL0 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NYK3 A0A8I3PJY6 A0A8I3PWQ1 A0A8I3S5D3 A0A8I3SAY5 J9P3I7 Q20FD0	FGF10 FGF17 FGF18 FGF22 FGF23 FGF3 FGF3A FGF4 FGF5 FGF7A FGF8 FGF8B FGFRL1 SPRED1 SPRED2	Canis familiaris (dog)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 2 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET	A0A8I3MIM0 A0A8I3MPM4 A0A8I3MZL3 A0A8I3N687 A0A8I3NFN9 A0A8I3NRK7 A0A8I3NSG2 A0A8I3NZW4 A0A8I3PA80 A0A8I3PDC9 A0A8I3PMW4 A0A8I3PU75 A0A8I3PXQ6 A0A8I3Q329 A0A8I3RZH1 A0A8I3S7C1 A0A8I3SAG0 E2RRP8 Q5U9D0	FGF21 FGF8C MFSD4B SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Canis familiaris (dog)	G58161NS G70323CJ
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A0B4J199 A0A8I3NKX5 A0A8I3NNZ2	FGF23 FGF8B FGFR1 KL	Canis familiaris (dog)
Extracellular matrix organization	Fibronectin	A0A8I3PED8	FN1	Canis familiaris (dog)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	A0A8I3PPB5 A0A8I3S5V4	FN3K FN3KRP	Canis familiaris (dog)
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3NGY1 A0A8I3NXI8 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PIK3CA PIK3R1	Canis familiaris (dog)
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A8I3NGY1 A0A8I3NXI8 A0A8I3PMT9 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PTPN11	Canis familiaris (dog)
Galactose catabolism	Galactokinase 1 Galactokinase Galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase	A0A8I3P3X5 A0A8I3PNL4 A0A8I3PT77 Q9GKK4	GALE GALK1 GALT H3-3B	Canis familiaris (dog)	G93924TT
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A8I3N0E0 A0A8I3N240 A0A8I3N9K8 A0A8I3PDQ2 A0A8I3QZQ9	GJA10 GJC1 GJD2 PANX PANX1 PANX2	Canis familiaris (dog)
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3E Glycine receptor alpha 1 Glycine receptor alpha 2 Glycine receptor alpha 3 Glycine receptor beta	A0A8I3MA77 A0A8I3MAG0 A0A8I3MZA4 A0A8I3NSZ3 A0A8I3P3M8 A0A8I3PQC9 A0A8I3Q2Z5 A0A8I3Q6S9 A0A8I3S5H9	GLRA1 GLRA2 GLRA3 GLRB HTR3A HTR3B HTR3C HTR3E LOC478649	Canis familiaris (dog)
Signaling by ROBO receptors	Glypican-1 Slit guidance ligand 2 Slit guidance ligand 3	A0A8I3MRE2 A0A8I3NQC4 A0A8I3Q4U0	GPC1 SLIT2 SLIT3	Canis familiaris (dog)

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