GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **268** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
FGFR3c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Polypeptide N-acetylgalactosaminyltransferase Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P0X5 A0A8I3PJY6 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GALNT3	Canis familiaris (dog)
FGFR2c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NTD6 A0A8I3NV07 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2	Canis familiaris (dog)
FGFR2b ligand binding and activation	Fibroblast growth factor 7 Fibroblast growth factor binding protein 1 Fibroblast growth factor binding protein 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein	A0A8I3MH10 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3Q445 P79150	FGF1 FGF10 FGF22 FGF3 FGF7 FGFBP1 FGFBP3 FGFR2 KGF	Canis familiaris (dog)
FGFR1c ligand binding and activation	Anosmin 1 Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GIPC PDZ domain containing family member 1 Multifunctional fusion protein Transforming growth factor beta receptor 3	A0A0B4J199 A0A7U3JWB8 A0A8I3NHF3 A0A8I3NNZ2 A0A8I3NTD6 A0A8I3NV07 A0A8I3NZI6 A0A8I3PDK4 A0A8I3PJY6 A0A8I3S906 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	ANOS1 FGF1 FGF17 FGF20 FGF23 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 GIPC1 TGFBR3	Canis familiaris (dog)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A0B4J199 A0A8I3NKX5 A0A8I3NNZ2	FGF23 FGF8B FGFR1 KL	Canis familiaris (dog)
FGFR1b ligand binding and activation	Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GIPC PDZ domain containing family member 1 Multifunctional fusion protein Transforming growth factor beta receptor 3	A0A8I3MP09 A0A8I3NHF3 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NV07 A0A8I3NYK3 A0A8I3NZI6 A0A8I3PDK4	FGF1 FGF10 FGF22 FGF3 FGFR1 GIPC1 TGFBR3	Canis familiaris (dog)
FCGR activation	Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3MFY1 A0A8I3ML64 A0A8I3MV98 A0A8I3NEM6 A0A8I3NQX3 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P3X1 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QHH1 A0A8I3QQ00 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S4F9 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 A0A8I3SBF9 E2RP87	CD247 CD3G FCGR1A FCGR2B FCGR3A FGR FYN HCK LOC478984 LYN SRC SYK YES1	Canis familiaris (dog)
Extracellular matrix organization	Fibronectin	A0A8I3PED8	FN1	Canis familiaris (dog)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Caveolin-1 Caveolin-2 EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 G protein subunit alpha transducin 3 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Matrix metallopeptidase 7 Matrix metalloproteinase-9 Palmitoyltransferase Palmitoyltransferase Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1 Tyrosine-protein kinase receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase type I protein arginine methyltransferase	A0A5F4C2B1 A0A8I3MAV6 A0A8I3MCQ8 A0A8I3ME07 A0A8I3MGS0 A0A8I3MHA7 A0A8I3MM75 A0A8I3MN99 A0A8I3MNZ2 A0A8I3MT80 A0A8I3MYE3 A0A8I3MZG1 A0A8I3N081 A0A8I3N0H9 A0A8I3N8T5 A0A8I3N971 A0A8I3NI71 A0A8I3NMY1 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NUU1 A0A8I3P3M1 A0A8I3P478 A0A8I3P519 A0A8I3P7L3 A0A8I3PJF2 A0A8I3PQY2 A0A8I3PS34 A0A8I3PV05 A0A8I3Q314 A0A8I3Q5L9 A0A8I3RPS3 A0A8I3RQ77 A0A8I3RRT3 A0A8I3RSE4 A0A8I3RYJ5 A0A8I3RYN2 A0A8I3S0D0 A0A8I3S3N2 A0A8I3S583 A0A8I3SBF9 O46550 O97564 P33724 P38400 P62872 P63210 P79147 Q6Y4Q5	AREG BTC CAV CAV-2 CAV1 CAV2 EGF EGFR EPGN EREG ESR1 ESR2 GNAI1 GNAI2 GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 HBEGF IGF1R LOC100856339 LOC119863873 MMP2 MMP3 MMP7 MMP9 PIK3CA PIK3R1 PIK3R2 PRMT1 PTK2 S1PR3 SHC1 SPHK1 SRC STRN TGFA ZDHHC21 ZDHHC7	Canis familiaris (dog)
Erythrocytes take up oxygen and release carbon dioxide	Ammonium transporter Rh type A Anion exchange protein Aquaporin-1 Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Globin A2 Globin domain-containing protein	A0A1K0GGH0 A0A8I3MCD6 A0A8I3MZM2 A0A8I3P092 A0A8I3Q3H0 A0A8I3S2I1 Q2Z1P8 Q9N2J4	AQP1 CA1 CA2 CA4 GLNA2 GLNA3 HBQ1 LOC609402 RHAG SLC4A1	Canis familiaris (dog)
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter Rh type A Anion exchange protein Aquaporin-1 Carbonic anhydrase Carbonic anhydrase Carbonic anhydrase Cytochrome b5 reductase 4 Globin A2 Globin domain-containing protein NADH-cytochrome b5 reductase NADH-cytochrome b5 reductase cytochrome-b5 reductase	A0A1K0GGH0 A0A8I3MCD6 A0A8I3MZM2 A0A8I3NK48 A0A8I3NSR4 A0A8I3NV71 A0A8I3P092 A0A8I3Q3H0 A0A8I3RYD7 A0A8I3S2I1 Q2Z1P8 Q9N2J4	AQP1 CA1 CA2 CA4 CYB5R1 CYB5R2 CYB5R4 CYB5RL GLNA2 GLNA3 HBQ1 LOC609402 RHAG SLC4A1	Canis familiaris (dog)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Transient receptor ion channel domain-containing protein Transient receptor potential cation channel subfamily C member 3 Transient receptor potential cation channel subfamily C member 7	A0A8I3MK71 A0A8I3NKB2 A0A8I3NUS5 A0A8I3NX68 A0A8I3P313 A0A8I3PPB8 A0A8I3PV78 A0A8I3PW88 A0A8I3Q0A9 A0A8I3Q2P2 A0A8I3QCF1 A0A8I3S1Y6 A0A8I3S3K0	ITPR1 ITPR2 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRPC3 TRPC6 TRPC7	Canis familiaris (dog)
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A8I3N0E0 A0A8I3N240 A0A8I3N9K8 A0A8I3PDQ2 A0A8I3QZQ9	GJA10 GJC1 GJD2 PANX PANX1 PANX2	Canis familiaris (dog)
Eicosanoid ligand-binding receptors	G-protein coupled receptors family 1 profile domain-containing protein	A0A8I3PXC2	OXER1	Canis familiaris (dog)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor	A0A8I3MAV6 A0A8I3RRT3	ESR1 ESR2	Canis familiaris (dog)
EPHB-mediated forward signaling	Actin gamma 1 Actin, cytoplasmic 1 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Arp2/3 complex 34 kDa subunit Cell division control protein 42 homolog Focal adhesion kinase 1 GTPase HRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Intersectin 1 RAS p21 protein activator 1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 28 Rho-associated protein kinase 2 Rho-associated protein kinase TIAM Rac1 associated GEF 1 Transforming protein RhoA Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein WASP like actin nucleation promoting factor non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I3MEB5 A0A8I3ML64 A0A8I3MNR2 A0A8I3MPK0 A0A8I3MVD4 A0A8I3MXJ0 A0A8I3N156 A0A8I3N1W7 A0A8I3NE73 A0A8I3NEW9 A0A8I3NH46 A0A8I3NMF7 A0A8I3NMY1 A0A8I3P3X1 A0A8I3P9Q7 A0A8I3PDZ1 A0A8I3PGP9 A0A8I3PH24 A0A8I3PPA3 A0A8I3PPQ5 A0A8I3PUN0 A0A8I3PVV6 A0A8I3Q1I3 A0A8I3Q2I4 A0A8I3SAZ7 A0A8I3SBF9 F1PHV6 O18840 P60952 P62999 Q5R1P0 Q5R1P3	ACTB ACTG1 ACTR2 ACTR3 ARHGEF28 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CDC42 FYN GRIN1 GRIN2B HRAS KALRN LOC119867035 LYN NMDAR1 PAK1 PTK2 RAC1 RASA1 RHOA ROCK1 ROCK2 SRC TIAM1 WASL YES1	Canis familiaris (dog)
EPH-Ephrin signaling	EPH receptor A10 EPH receptor B6 EPH-related receptor tyrosine kinase ligand 7 Ephrin A2 Ephrin A3 Ephrin A4 Ephrin B3 Ephrin type-B receptor 3 Ephrin-A1 Ephrin-B2 Uncharacterized protein receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A8I3MB23 A0A8I3MBN5 A0A8I3MD88 A0A8I3MVS4 A0A8I3N250 A0A8I3NEL5 A0A8I3NQ24 A0A8I3NR10 A0A8I3NS68 A0A8I3NYD1 A0A8I3PTE3 A0A8I3PZY2 A0A8I3Q5U0 A0A8I3QB00 A0A8I3RP21 A0A8I3RVX4 A0A8I3RZP3 A0A8I3S0G7 A0A8I3SCP8 B0LDS6	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB2 EPHB3 EPHB4 EPHB6 efnB2	Canis familiaris (dog)
EGFR Transactivation by Gastrin	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1 small monomeric GTPase	A0A8I3PSP7 A0A8I3PT69 A0A8I3PUQ8 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RPS3 A0A8I3RYJ5 A0A8I3S3D9 Q6Y4Q5	EGFR GRB2 HBEGF HRAS KRAS MMP3 NRAS PRKCA SOS1	Canis familiaris (dog)
ECM proteoglycans	Aggrecan core protein Agrin Biglycan Brevican core protein Cartilage oligomeric matrix protein Collagen type IX alpha 1 chain Collagen type IX alpha 2 Collagen type IX alpha 3 chain Decorin Dentin matrix acidic phosphoprotein 1 Dentin sialophosphoprotein Fibronectin type-III domain-containing protein Hyaluronan and proteoglycan link protein 1 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 7 Integrin subunit alpha 8 Integrin subunit alpha 9 Integrin subunit alpha D Integrin subunit alpha V Matrilin 1 Matrilin 3 Matrilin 4 Neurocan Plasminogen activator inhibitor 1 SPARC Tenascin C Tenascin R Versican core protein Vitronectin	A0A8I3MC22 A0A8I3MDS4 A0A8I3MMP8 A0A8I3MS95 A0A8I3MWF4 A0A8I3N567 A0A8I3N600 A0A8I3N8Z0 A0A8I3NBB5 A0A8I3NFV4 A0A8I3NG24 A0A8I3NJU0 A0A8I3NL86 A0A8I3NUF9 A0A8I3P2A0 A0A8I3P4U9 A0A8I3P613 A0A8I3P787 A0A8I3P874 A0A8I3PAS0 A0A8I3PHY6 A0A8I3PLC3 A0A8I3PMU9 A0A8I3PZR7 A0A8I3QCJ7 A0A8I3RVA0 A0A8I3RVR5 A0A8I3RYZ7 A0A8I3S0I3 A0A8I3S0V6 A0A8I3S0V9 A0A8I3S700 E2DP67 Q29393	ACAN AGRN BCAN BGN COL9A1 COL9A2 COL9A3 COMP DCN DCN1C DMP1 DSPP HAPLN1 ITGA2 ITGA2B ITGA7 ITGA8 ITGA9 ITGAD ITGAV ITGB1 ITGB3 ITGB5 ITGB6 MATN1 MATN3 MATN4 NCAN SEBOX SERPINE1 SPARC TNC TNR VCAN	Canis familiaris (dog)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	A0A8I3NGY1 Q867B7	HGF MET	Canis familiaris (dog)
Downstream signaling of activated FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PDH2 A0A8I3PJY6 A0A8I3RV97 A0A8I3SAY5 A0A8I3SCU1 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FLRT1 FLRT2 FLRT3 KL	Canis familiaris (dog)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk BCAR1 scaffold protein, Cas family member CRK like proto-oncogene, adaptor protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B RAS p21 protein activator 1 Rap guanine nucleotide exchange factor 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N1K5 A0A8I3N488 A0A8I3N971 A0A8I3N974 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NGQ0 A0A8I3NID0 A0A8I3P5F5 A0A8I3PDZ1 A0A8I3PMT9 A0A8I3PN08 A0A8I3PSA1 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RV66 A0A8I3RVE7 A0A8I3RXB9 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S602 A0A8I3S8J3 A0A8I3SBF9 A0A8I3SCI7 Q6Q7I7	BCAR1 CRK CRKL GRB2 GRB7 HRAS KRAS NCK1 NCK2 NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PTPN11 RAPGEF1 RASA1 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6	Canis familiaris (dog)
Downstream TCR signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 BCL10 immune signaling adaptor Caspase recruitment domain family member 11 Cullin 1 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme F-box and WD repeat domain containing 11 Ig-like domain-containing protein IkappaB kinase Immunoglobulin V-set domain-containing protein Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein kinase C RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha variable 29/delta variable 5 T cell receptor associated transmembrane adaptor 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ82 A0A8I3MKK6 A0A8I3MKL4 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MNA4 A0A8I3MNI0 A0A8I3MQX7 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MV98 A0A8I3MZ69 A0A8I3N0P1 A0A8I3N165 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N7L6 A0A8I3N952 A0A8I3N971 A0A8I3N9G3 A0A8I3NAC6 A0A8I3NFB9 A0A8I3NH42 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NT57 A0A8I3NT75 A0A8I3NTK0 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NW81 A0A8I3NXK9 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4A1 A0A8I3P4Z1 A0A8I3P564 A0A8I3P6I7 A0A8I3P6M2 A0A8I3PAB8 A0A8I3PAP4 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PFI5 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PMA2 A0A8I3PR42 A0A8I3PWT3 A0A8I3PZT2 A0A8I3QV78 A0A8I3QYD0 A0A8I3RR14 A0A8I3RRK6 A0A8I3RRL7 A0A8I3RRR7 A0A8I3RT39 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S023 A0A8I3S1Z6 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S3N2 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P27597 P33705 P60483 P63050 Q5W412 Q5W416 Q6F3J0	BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CDC34 CHUK CUL1 DLA-DQA1 DLA-DRA FBXW11 HLA-DQB2 IKBKB IKBKG INPP5D LCK LOC100686569 LOC100687259 LOC119881719 LOC610717 MALT1 MAP3K7 MMAC1 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKCQ PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN RELA RIPK2 RPS27A SKP1 TAB2 TRAF6 TRAT1 TRAV29DV5 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2N	Canis familiaris (dog)
Digestion of dietary carbohydrate	Alpha-amylase Lactase Maltase-glucoamylase Sucrase-isomaltase chitinase	A0A8I3MKS5 A0A8I3NDB4 A0A8I3P4Z5 A0A8I3QYQ3 J9PAL7	CHIA LCT LOC119879923 LOC119881526 MGAM SI	Canis familiaris (dog)	G58161NS G74621DY G93924TT G96370VA
Digestion	Alkaline phosphatase Guanylate cyclase activator 2B Guanylate cyclase Guanylin Pirin	A0A8I3N4X7 A0A8I3P3W4 A0A8I3PB32 A0A8I3PK10 A0A8I3QK41	ALPI GUCA2A GUCA2B GUCY2C PIR	Canis familiaris (dog)

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