GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **268** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
FGFR3c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Polypeptide N-acetylgalactosaminyltransferase Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P0X5 A0A8I3PJY6 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GALNT3	Canis familiaris (dog)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty related EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2 Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MXL0 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NYK3 A0A8I3PJY6 A0A8I3PWQ1 A0A8I3S5D3 A0A8I3SAY5 J9P3I7 Q20FD0	FGF10 FGF17 FGF18 FGF22 FGF23 FGF3 FGF3A FGF4 FGF5 FGF7A FGF8 FGF8B FGFRL1 SPRED1 SPRED2	Canis familiaris (dog)
FRS-mediated FGFR1 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NM39 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FRS2 FRS3 GRB2 HRAS KL KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
PI-3K cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MP09 A0A8I3N971 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FRS2 GAB1 GRB2 KL PIK3CA PIK3R1 PTPN11	Canis familiaris (dog)
Downstream signaling of activated FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PDH2 A0A8I3PJY6 A0A8I3RV97 A0A8I3SAY5 A0A8I3SCU1 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FLRT1 FLRT2 FLRT3 KL	Canis familiaris (dog)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 GRB2 HRAS KL KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
FGFR2c ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NTD6 A0A8I3NV07 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2	Canis familiaris (dog)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A0B4J199 A0A8I3NKX5 A0A8I3NNZ2	FGF23 FGF8B FGFR1 KL	Canis familiaris (dog)
FGFR2b ligand binding and activation	Fibroblast growth factor 7 Fibroblast growth factor binding protein 1 Fibroblast growth factor binding protein 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein	A0A8I3MH10 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3Q445 P79150	FGF1 FGF10 FGF22 FGF3 FGF7 FGFBP1 FGFBP3 FGFR2 KGF	Canis familiaris (dog)
FGFR1b ligand binding and activation	Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GIPC PDZ domain containing family member 1 Multifunctional fusion protein Transforming growth factor beta receptor 3	A0A8I3MP09 A0A8I3NHF3 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NV07 A0A8I3NYK3 A0A8I3NZI6 A0A8I3PDK4	FGF1 FGF10 FGF22 FGF3 FGFR1 GIPC1 TGFBR3	Canis familiaris (dog)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 2 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET	A0A8I3MIM0 A0A8I3MPM4 A0A8I3MZL3 A0A8I3N687 A0A8I3NFN9 A0A8I3NRK7 A0A8I3NSG2 A0A8I3NZW4 A0A8I3PA80 A0A8I3PDC9 A0A8I3PMW4 A0A8I3PU75 A0A8I3PXQ6 A0A8I3Q329 A0A8I3RZH1 A0A8I3S7C1 A0A8I3SAG0 E2RRP8 Q5U9D0	FGF21 FGF8C MFSD4B SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Canis familiaris (dog)	G58161NS G70323CJ
Interferon gamma signaling	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Y-box-binding protein 1 Y-box-binding protein 1 Y-box-binding protein 1 calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A8I3MY73 A0A8I3NIS8 A0A8I3NMP2 A0A8I3NPS8 A0A8I3NU62 A0A8I3NVH4 A0A8I3NXV5 A0A8I3PF62 A0A8I3PSA1 A0A8I3PWC6 A0A8I3PZJ7 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 A0A8I3RWC7 P42161	CAMK2A CAMK2B CAMK2G IFNG IFNGR1 IFNGR2 JAK1 JAK2 LOC479011 MAPK1 MAPK3 PRKCD PTPN6 SOCS3 STAT1 YBX1	Canis familiaris (dog)
IFNG signaling activates MAPKs	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein	A0A8I3MY73 A0A8I3NVH4 A0A8I3PZA0 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 RAF1	Canis familiaris (dog)
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1	Canis familiaris (dog)
Extracellular matrix organization	Fibronectin	A0A8I3PED8	FN1	Canis familiaris (dog)
MET activates PTK2 signaling	Focal adhesion kinase 1 Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 3 Laminin subunit alpha 4 Multiple EGF like domains 6 Tyrosine-protein kinase	A0A8I3MC22 A0A8I3MMP8 A0A8I3NFG9 A0A8I3NGY1 A0A8I3NMY1 A0A8I3PA47 A0A8I3PGZ1 A0A8I3SBF9 Q867B7	HGF ITGA2 ITGA3 ITGB1 LAMA4 MEGF6 MET PTK2 SRC	Canis familiaris (dog)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormone subunit beta 5 Glycoprotein hormones alpha chain Gonadotropin-releasing hormone receptor Progonadoliberin Thyrotropin receptor Thyrotropin subunit beta Uncharacterized protein	A0A0F7RPW1 A0A0F7RQS3 A0A8I3MZ56 A0A8I3N8M9 A0A8I3PVK9 A0A8I3Q1X1 A0A8I3RXY8 E2RJZ8 P14763	CGA FSHB FSHR GNRH1 GNRHR GPA1 GPB5 GPHA2 GPHB5 TSHB TSHR	Canis familiaris (dog)
GDP-fucose biosynthesis	Fucose kinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A8I3MTB3 A0A8I3NTS0 A0A8I3NVI9 A0A8I3PWT5 A0A8I3Q1E5 A0A8I3RTZ0	FCSK FPGT FUOM GFUS GMDS SLC35C1	Canis familiaris (dog)	G85196CF G96881BQ
Amine ligand-binding receptors	G protein-coupled receptor 143	A0A8I3PL97	GPR143	Canis familiaris (dog)
Eicosanoid ligand-binding receptors	G-protein coupled receptors family 1 profile domain-containing protein	A0A8I3PXC2	OXER1	Canis familiaris (dog)
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3NGY1 A0A8I3NXI8 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PIK3CA PIK3R1	Canis familiaris (dog)
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A8I3NGY1 A0A8I3NXI8 A0A8I3PMT9 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PTPN11	Canis familiaris (dog)
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A8I3N3U3 A0A8I3NGY1 A0A8I3NUU1 A0A8I3PS27 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3QSS9 A0A8I3S3D9 Q867B7	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1	Canis familiaris (dog)
EGFR Transactivation by Gastrin	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1 small monomeric GTPase	A0A8I3PSP7 A0A8I3PT69 A0A8I3PUQ8 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RPS3 A0A8I3RYJ5 A0A8I3S3D9 Q6Y4Q5	EGFR GRB2 HBEGF HRAS KRAS MMP3 NRAS PRKCA SOS1	Canis familiaris (dog)
Galactose catabolism	Galactokinase 1 Galactokinase Galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase	A0A8I3P3X5 A0A8I3PNL4 A0A8I3PT77 Q9GKK4	GALE GALK1 GALT H3-3B	Canis familiaris (dog)	G93924TT

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